Analgesic Efficacy of Fascia Iliaca Compartment Block Compared With Intrathecal Nalbuphine for Hip Surgery Under Spinal Anesthesia

Analgesic Efficacy of Fascia Iliaca Compartment Block Compared With Intrathecal Nalbuphine for Hip Surgery Under Spinal Anesthesia: a Randomized Controlled Trial

It is already known that fascia iliaca compartment block and intrathecal nalbuphine are very effective ways in postoperative pain control in patients having hip surgeries.

Study Overview

• Status: Recruiting
• Conditions: Postoperative Pain
• Intervention / Treatment: Other: US-guided fascia iliaca compartment block (FICB) and spinal anesthesia; Drug: Intrathecal nalbuphine and spinal anesthesia; Other: Spinal anesthesia

• Study Type: Interventional
• Enrollment (Estimated): 120
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Egypt
  • Cairo, Egypt
    • Recruiting
    • Ain-Shams University Hospitals
    • Contact: Ibrahim Mamdouh Esmat; Phone Number: 01001241928; Email: ibrahim_mamdouh@med.asu.edu.eg

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: No

Description

Inclusion Criteria:

• American Society of Anesthesiologists (ASA) score (ASA I- ASA II).
• Age ≥ 21years.
• Body mass index < 35 kg/m2

Exclusion Criteria:

• Patient's refusal.
• Known coagulopathy.
• Known peripheral neuropathy or neurological deficits.
• Known allergy to study drugs

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Prevention
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Double

Number of Arms

3

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Other: Spinal anesthesia	Other: Spinal anesthesia; Spinal anesthesia
Active Comparator: US-guided fascia iliaca compartment block (FICB) and spinal anesthesia	Other: US-guided fascia iliaca compartment block (FICB) and spinal anesthesia; US-guided fascia iliaca compartment block (FICB) and spinal anesthesia
Active Comparator: Intrathecal nalbuphine and spinal anesthesia	Drug: Intrathecal nalbuphine and spinal anesthesia; intrathecal nalbuphine and spinal anesthesia

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Time to first rescue analgesia (minutes).	Time to first rescue analgesia (minutes).	in the first 24 hours after surgery

Collaborators and Investigators

• Sponsor: Ain Shams University

Study record dates

Study Major Dates

• Study Start (Actual): February 18, 2025
• Primary Completion (Estimated): March 31, 2026
• Study Completion (Estimated): March 31, 2026

Study Registration Dates

• First Submitted: February 5, 2025
• First Submitted That Met QC Criteria: February 5, 2025
• First Posted (Actual): February 10, 2025

Study Record Updates

• Last Update Posted (Actual): November 19, 2025
• Last Update Submitted That Met QC Criteria: November 15, 2025
• Last Verified: November 1, 2025

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Pain; Neurologic Manifestations; Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Signs and Symptoms; Pain, Postoperative; Anesthesia and Analgesia; Anesthesia, Conduction; Anesthesia; Anesthesia, Spinal
• Other Study ID Numbers: FMASU-MS 72 / 2025

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No