Transfusion Prediction in Major Abdominal Surgery

February 21, 2025 updated by: Ji-Hoon Sim, Asan Medical Center

Development and Validation of a Predictive Model for Transfusion in Major Abdominal Surgery

The transfusion nomogram, integrating preoperative variables, may effectively predict intraoperative transfusion in major abdominal surgery.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Actual)

128749

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Sampling Method

Non-Probability Sample

Study Population

This study includes adult patients (≥18 years old) who underwent major abdominal surgery at a tertiary medical center. The study population consists of patients with available preoperative clinical and laboratory data, allowing for the development of a predictive model for intraoperative blood transfusion. Patients with known hematologic disorders, coagulopathy, or prior transfusion before surgery are excluded to minimize confounding factors.

Description

Inclusion Criteria:

  • Patients aged 18 years and older who underwent major abdominal surgery

Exclusion Criteria:

  • Patients with known hematologic disease or coagulopathy
  • Patients who received a blood transfusion before surgery
  • Patients with incomplete data or missing laboratory values

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Intraoperative transfusion
Time Frame: From surgical incision to the end of surgery
The primary outcome measure is the occurrence of intraoperative blood transfusion. This includes any administration of red blood cells, plasma, or platelets during the surgical procedure. The study aims to predict transfusion requirements based on preoperative clinical factors.
From surgical incision to the end of surgery

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Asan Medical Center

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

June 30, 2024

Primary Completion (Actual)

December 20, 2024

Study Completion (Actual)

January 2, 2025

Study Registration Dates

First Submitted

February 21, 2025

First Submitted That Met QC Criteria

February 21, 2025

First Posted (Actual)

March 25, 2025

Study Record Updates

Last Update Posted (Actual)

March 25, 2025

Last Update Submitted That Met QC Criteria

February 21, 2025

Last Verified

February 1, 2025

More Information

Terms related to this study

Other Study ID Numbers

  • AMC (2024-1087)

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

product manufactured in and exported from the U.S.

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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