Factors Affecting Outcomes of Using Diode Laser Both 980 nm Wave Length and 450 Wavelength on Benign Laryngeal Lesions in Comparison to Traditional Cold Instrumentations as Regard Parameters of Laser Device, Nature of Lesion and Patient Factors (LASER)

August 18, 2025 updated by: Mohamed Abdelsamei Abdelgalil, Sohag University

Factors Affecting the Outcomes of Using the Diode Laser in Benign Laryngeal Lesions

Studying the different Factors affecting the outcomes of using diode laser both 980 nm wave length and 450 wavelength on benign laryngeal lesions in comparison to traditional cold instrumentations

Study Overview

Status

Enrolling by invitation

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Estimated)

108

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Egypt
      • Sohag, Egypt, 82511
        • Sohag University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

- All patients with benign laryngeal lesions

Exclusion Criteria:

  • patients presenting with or have history of malignant laryngeal lesion

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Double

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: Group (A)
using diode laser 980nm wavelength in benign laryngeal lesions
Procedure: using diode laser 980nm wavelength in benign laryngeal lesions
using diode laser 980nm wavelength in treatment of benign laryngeal lesions
Active Comparator: Group (B)
using diode laser 450nm wavelength in benign laryngeal lesions
Procedure: using diode laser 450nm wavelength in benign laryngeal lesions
using diode laser 450nm wavelength in treatment of benign laryngeal lesions
Active Comparator: Group (C)
using traditional cold instrumentations in benign laryngeal lesions
Procedure: using traditional cold instrumentations in benign laryngeal lesions
using traditional cold instrumentations in treatment of benign laryngeal lesions

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
change in voice handicap index Arabic version (VHI-Arabic)
Time Frame: 2 months after treatment
change in Voice handicap index Arabic version from baseline before treatment and after treatment
2 months after treatment
change in voice acoustic analysis
Time Frame: 2 months after treatment
change in voice acoustic analysis including change in jitter and shimmer values from baseline preoperative and 2 months after treatment
2 months after treatment

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Sohag University

Investigators

  • Principal Investigator: Mohammed Abdu Elsamea, Assistant lecturer, Sohag University

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

October 1, 2024

Primary Completion (Estimated)

December 31, 2025

Study Completion (Estimated)

February 28, 2026

Study Registration Dates

First Submitted

March 25, 2025

First Submitted That Met QC Criteria

April 2, 2025

First Posted (Actual)

April 6, 2025

Study Record Updates

Last Update Posted (Actual)

August 24, 2025

Last Update Submitted That Met QC Criteria

August 18, 2025

Last Verified

August 1, 2025

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • Soh-Med-24-12-3MD

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

UNDECIDED

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

product manufactured in and exported from the U.S.

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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