Artificial Intelligence to Detect Missed Root Canals in Previously Treated Lower Back Teeth Using 3D Dental Imaging (CBCT) (cone beam CT)

Accuracy of Artificial Intelligence Technology to Detect the Presence of Missed Canals of Endodontically Treated Mandibular Second Molar : Diagnostic Accuracy Experimental Study

Aims to detect the Accuracy of Artificial Intelligence Technology in Detecting the Presence of Missed Canals of Endodontically Treated Mandibular Second Molar. Will Artificial intelligence software, CBCT and Clinical visual examination with dental operating microscope differs in the detection of presence of missed canals of endodontically treated human mandibular second molar ?

Study Overview

• Status: Enrolling by invitation
• Conditions: Presence of Missed Canals; Morphological Variation
• Intervention / Treatment: Procedure: Root Canal Retreatment

• Study Type: Interventional
• Enrollment (Estimated): 3
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Egypt
  • Cairo, Egypt, 11835
    • Faculty of Oral and Dental Medicine future university

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult
• Accepts Healthy Volunteers: Yes

Description

Inclusion Criteria:

- 1) Patients must be medically free from any systemic disease that can affect root canal treatment.

2) Age range of the patient should be between 18 - 50 years old. 3) No sex predilection. 4) Patients must have good oral hygiene. 5) Patients with root canal-treated teeth. 6) Restorable teeth. 7) Positive patient acceptance for participating in the study. 8) Patients can sign informed consent.

Exclusion Criteria:

- 1) Patients with very poor oral hygiene. 2) Patients above 50 years and below 18 years. 3) Pregnant women after taking detailed history and pregnancy test must be in the first visit.

4) Psychologically disturbed patients. 5) Tooth periodontally affected with grade 2 or 3 mobility. 6) Non restorable teeth. 7) Tooth with abnormal anatomy and calcified canals.

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Diagnostic
• Allocation: Randomized
• Interventional Model: Sequential Assignment
• Masking: Single

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Active Comparator: Presence of missed canals	Procedure: Root Canal Retreatment; if Retreatment was needed, local anesthesia using 1.8 ml (one cartridge) of 4% articaine with 1:100,000 epinephrine local anesthetic solution, administered with end -loading cartridge aspirating syringe and a 27-gauge long needle. Under rubber dam isolation, All carious tissue and existing coronal restorations were thoroughly removed using a round bur, an endodontic access cavity, canal preparation and removal of existing root canal filling, irrigation with 2.6% NAOCL and saline, determining the working length using apex locator and PA radiograph, to be 0.5 to 1 mm shorter than radiographic apex, Drying the canal with paper point and obturation to achieve a dense, well adapted Monoblock obturation. A post-obturation periapical radiograph was taken to confirm the quality of the fill in terms of length, density, then sealed by a temporary restorative material.; Other Names: Re-RCT
Active Comparator: Morphological variation	Procedure: Root Canal Retreatment; if Retreatment was needed, local anesthesia using 1.8 ml (one cartridge) of 4% articaine with 1:100,000 epinephrine local anesthetic solution, administered with end -loading cartridge aspirating syringe and a 27-gauge long needle. Under rubber dam isolation, All carious tissue and existing coronal restorations were thoroughly removed using a round bur, an endodontic access cavity, canal preparation and removal of existing root canal filling, irrigation with 2.6% NAOCL and saline, determining the working length using apex locator and PA radiograph, to be 0.5 to 1 mm shorter than radiographic apex, Drying the canal with paper point and obturation to achieve a dense, well adapted Monoblock obturation. A post-obturation periapical radiograph was taken to confirm the quality of the fill in terms of length, density, then sealed by a temporary restorative material.; Other Names: Re-RCT

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
Presence of missed canals	Pre Operative and At the end of the treatment within 1 week

Secondary Outcome Measures

Outcome Measure	Time Frame
Morphological variation	Pre Operative and At the end of the treatment within 1 week

Collaborators and Investigators

• Sponsor: Future University in Egypt

Study record dates

Study Major Dates

• Study Start (Actual): December 25, 2024
• Primary Completion (Estimated): October 29, 2025
• Study Completion (Estimated): October 29, 2025

Study Registration Dates

• First Submitted: July 1, 2025
• First Submitted That Met QC Criteria: July 11, 2025
• First Posted (Actual): July 22, 2025

Study Record Updates

• Last Update Posted (Actual): July 22, 2025
• Last Update Submitted That Met QC Criteria: July 11, 2025
• Last Verified: October 1, 2024

More Information

Terms related to this study

• Keywords: Artificial intelligence; CBCT; AI; Morphological variation; Presence of missed canals; Clinical visual examination; dental operating microscope; mandibular second molar
• Other Study ID Numbers: FUE.REC(47)11-2024

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: UNDECIDED

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No