- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT07093658
- Original Trial
High vs Low Fall Injuries in Asia: 7-Year Multicenter Study
July 23, 2025 updated by: Tse-Hao Chen, Mackay Memorial Hospital
Epidemiology and Outcome of High Versus Low Fall Injury in Asia Countries: A 7-year Multicenter Cohort Study
This multicenter study revealed a declining overall incidence of fall-related injuries, accompanied by a rising proportion of high falls, predominantly among non-elderly males.
Mortality risk increased significantly at fall heights of 3 and 6 meters, supporting current field triage thresholds.
Across both high and low falls, lower SpO₂ and GCS were key predictors of 30-day mortality, with head injury being an additional risk factor in low fall cases
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Study Type
Observational
Enrollment (Actual)
59099
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Adult
- Older Adult
Accepts Healthy Volunteers
Yes
Sampling Method
Non-Probability Sample
Study Population
This study included adult patients (aged ≥18 years) who were transported by emergency medical services (EMS) between January 2016 and December 2022.
Patients were excluded if they had missing data on age, sex, injury mechanism, systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR), oxygen saturation (SpO₂), Glasgow Coma Scale (GCS), Abbreviated Injury Scale (AIS) for each body region, Injury Severity Score (ISS), Revised Trauma Score (RTS), or fall height.
In addition, patients with missing records of 30-day mortality were excluded from the mortality cohort analysis.
Description
Inclusion Criteria:
- This study included adult patients (aged ≥18 years) who were transported by emergency medical services (EMS) between January 2016 and December 2022.
- Fall injury patients
Exclusion Criteria:
- missing data on age, sex, injury mechanism, systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR), oxygen saturation (SpO₂), Glasgow Coma Scale (GCS), Abbreviated Injury Scale (AIS) for each body region, Injury Severity Score (ISS), Revised Trauma Score (RTS), or fall height
- missing records of 30-day mortality
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
Cohorts and Interventions
Group / Cohort |
Intervention / Treatment |
|---|---|
|
Low fall injury group
|
High fall injury group
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
30-day mortality
Time Frame: 30-day
|
30-day mortality
|
30-day
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
General Publications
- Kim J, Shin SD, Im TH, Kug Jong Lee, Ko SB, Park JO, Ahn KO, Song KJ. Development and validation of the Excess Mortality Ratio-adjusted Injury Severity Score Using the International Classification of Diseases 10th Edition. Acad Emerg Med. 2009 May;16(5):454-464. doi: 10.1111/j.1553-2712.2009.00412.x.
- Kong SY, Shin SD, Tanaka H, Kimura A, Song KJ, Shaun GE, Chiang WC, Kajino K, Jamaluddin SF, Wi DH, Park JO, Moon SW, Ro YS, Cone DC, Holmes JF Jr. Pan-Asian Trauma Outcomes Study (PATOS): Rationale and Methodology of an International and Multicenter Trauma Registry. Prehosp Emerg Care. 2018 Jan-Feb;22(1):58-83. doi: 10.1080/10903127.2017.1347224. Epub 2017 Aug 9.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
January 1, 2016
Primary Completion (Actual)
December 1, 2022
Study Completion (Actual)
December 1, 2024
Study Registration Dates
First Submitted
July 23, 2025
First Submitted That Met QC Criteria
July 23, 2025
First Posted (Actual)
July 30, 2025
Study Record Updates
Last Update Posted (Actual)
July 30, 2025
Last Update Submitted That Met QC Criteria
July 23, 2025
Last Verified
July 1, 2025
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- 24MMHIS447e
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
NO
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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