Effect of Bicycle Ergometer Training on Fat Tissue Amount and Metabolism

May 10, 2026 updated by: Şule ŞİMŞEK, Pamukkale University

Effect of Bicycle Ergometer Training in Thermoneutral and Lightly Cold Ambient Temperatures on Fat Tissue Amount and Metabolism in Overweight and Obese Women

The aim of this study is to investigate the effect of endurance training performed with a bicycle ergometer at different ambient temperatures on the amount of fat tissue and fat tissue metabolism in overweight and obese women.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

This study will examine the effects of 12 weeks of endurance training on a bicycle ergometer at thermoneutral and slightly cold ambient temperatures on body composition, subcutaneous and visceral fat tissue thickness, and levels of irisin, leptin, adiponectin, apelin, IL-6 and FGF-21 in the blood of overweight and obese women.

Study Type

Interventional

Enrollment (Actual)

30

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Turkey (Türkiye)
    • Sarayköy
      • Denizli, Sarayköy, Turkey (Türkiye), 09200
        • Şule Şimşek

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

Being female,

  • Being between 20-40 years old,
  • Having a BMI between 25 and 34.9,
  • Having a waist circumference greater than 80 cm,
  • Not having participated in any exercise program in the last 3 months ,
  • Not having experienced a change of more than 10% in body weight in the last 6 months.

Exclusion Criteria:

  • On a weight loss diet,

    • Having cancer, unstable heart disease, cerebrovascular disease, metabolic disease, diabetes, hypertension, psychiatric disorders, or other conditions or neurological disorders,
    • Having a musculoskeletal disorder or any disease/injury that may affect participation in exercise training,
    • Participating in regular physical activity (at least 150 minutes of moderate-intensity physical activity or 75 minutes of vigorous-intensity physical activity or an equivalent combination of both during the week),
    • Being pregnant or breastfeeding,
    • Having undergone surgery for the treatment of obesity,
    • Receiving pharmacological treatment for obesity. Participants who did not attend more than 20% of the endurance training program will be excluded from the study.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Case group 1
participants trained in termoneutral ambient temperature
Other: endurance training with bicycle ergometer in termoneutral ambient temperature
trained with bicycle ergometer three times a week for three months.
Active Comparator: Case group 2
participants trained in lightly cold ambient temperature
Other: endurance training with bicycle ergometer in lightly cold ambient temperature
trained with bicycle ergometer three times a week for three months.
No Intervention: control group
participants do not trained

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
rate of BMI
Time Frame: baseline/ through study completion, an average 3 months
assesed with height and body weight
baseline/ through study completion, an average 3 months
analysis of biyoelectric impedans Bioelectrical impedance analysis
Time Frame: baseline/ through study completion, an average 3 months
assesed with with a Tanita BC 418 brand device.
baseline/ through study completion, an average 3 months
Ratio of waist-hip Waist hip ratio
Time Frame: baseline/ through study completion, an average 3 months
Waist and hip circumference will be measured with a tape measure.
baseline/ through study completion, an average 3 months
rate of subcutaneous and visceral adipose tissue thickness
Time Frame: baseline/ through study completion, an average 3 months
assesed with Ultrasonography
baseline/ through study completion, an average 3 months
concentration of serum irisin, leptin, adiponectin, apelin, İL-6 and FGF-21
Time Frame: baseline/ through study completion, an average 3 months
assesed with blood analysis
baseline/ through study completion, an average 3 months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Pamukkale University

Investigators

  • Study Director: Ummuhan Baş Aslan, Prof. Dr., Prof. Dr.

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

May 27, 2025

Primary Completion (Actual)

September 27, 2025

Study Completion (Actual)

April 27, 2026

Study Registration Dates

First Submitted

May 27, 2025

First Submitted That Met QC Criteria

December 3, 2025

First Posted (Actual)

December 4, 2025

Study Record Updates

Last Update Posted (Actual)

May 13, 2026

Last Update Submitted That Met QC Criteria

May 10, 2026

Last Verified

May 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 23.07.2024/13

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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