Virtual Microscopy Versus Optical Microscopy

December 11, 2025 updated by: Muhammad Aamir Latif

Virtual Microscopy Versus Optical Microscopy: Comparison of Two Teaching Methodologies for Achieving Specific Learning Outcomes in Medical Students.

The literature reveals ongoing debate regarding the relative effectiveness of Virtual Microscopy (VM) versus Optical Microscopy (OM) in achieving specific learning outcomes (SLOs). There remains a paucity of comprehensive, comparative research evaluating these methodologies against standardized learning outcomes in the medical undergraduate population. This instigated a comparison of VM and OM as teaching methodologies for pathology in medical education, specifically focusing on their effectiveness in achieving predetermined learning outcomes.

Study Overview

Status

Completed

Conditions

Detailed Description

It is now essential to thoroughly evaluate the pedagogical effects of these changing modalities due to the growing trend towards digital learning environments, which has been brought to light by recent global challenges to traditional classroom teaching. By methodically contrasting virtual and optical microscopy for teaching pathology to undergraduate medical students, this work can close this gap. It is anticipated that understanding the superior modality-more especially, how well it achieves predefined learning outcomes-will improve the optimization of pathology instruction in modern medical education and guide evidence-based curriculum selections.

Study Type

Interventional

Enrollment (Actual)

350

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

    • Punjab Province
      • Bahawalpur, Punjab Province, Pakistan, 63100
        • Quaid-E-Azam Medical College

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • Students of either gender
  • Aged 20-24 years
  • Studying in fourth-year MBBS
  • Willing to participate

Exclusion Criteria:

  • Students, absent during the interventions or assessments
  • Declined or withdrew consent at any stage

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Other
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Group I
Students were exposed to optical microscopy (OM); OM is the conventional method of using physical microscopes to examine microscope slides.
Students were exposed to optical microscopy (OM); OM is the conventional method of using physical microscopes to examine microscope slides.
Experimental: Group II
Students were exposed to virtual microscopy (VM); VM is a digital technology that allows students to view and analyze microscope slides through digital platforms.
Students were exposed to virtual microscopy (VM); VM is a digital technology that allows students to view and analyze microscope slides through digital platforms.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Perceptions and satisfaction
Time Frame: 3 hours
A five-point Likert scale assessed perceptions and satisfaction with the respective teaching methodology. The likert scale responses were graded as 1 for strongly disagree, 2 for disagree, 3 as neutral, 4 agree, and 5 strongly agree.
3 hours

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Investigators

  • Principal Investigator: Sadaf Shafique, FCPS, Quaid-E-Azam Medical College, Bahawalpur, Pakistan

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

August 1, 2024

Primary Completion (Actual)

October 30, 2024

Study Completion (Actual)

October 30, 2024

Study Registration Dates

First Submitted

December 11, 2025

First Submitted That Met QC Criteria

December 11, 2025

First Posted (Actual)

December 24, 2025

Study Record Updates

Last Update Posted (Actual)

December 24, 2025

Last Update Submitted That Met QC Criteria

December 11, 2025

Last Verified

December 1, 2025

More Information

Terms related to this study

Other Study ID Numbers

  • DR-SADAF-QAMC

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

IPD Plan Description

Data can be shared on a reasonable request.

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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