PICS Clinic Attendance and Recovery Engagement (PICS-CARE)

To identify relevant factors influencing attendance at appointments at the PICS outpatient clinic after intensive care treatment in order to derive targeted measures to increase the participation rate or send more targeted invitations.

Study Overview

• Status: Recruiting
• Conditions: Post-intensive Care Syndrome

Detailed Description

This retrospective study examines which factors influence patient attendance at structured follow-up appointments after intensive care treatment in the PICS outpatient clinic at Charité. The focus is on analyzing demographic, clinical, and care-related factors that influence actual participation in follow-up care after intensive care treatment.

• Study Type: Observational
• Enrollment (Estimated): 2500

Contacts and Locations

• Study Contact: Name: Claudia Spies, MD, Prof.; Phone Number: +49 30 450 551102; Email: claudia.spies@charite.de

Study Locations

• Germany
  • Berlin, Germany, 13353
    • Recruiting
    • Department of Anesthesiology and Intensive Care Medicine (CCM/CVK), Charité - Universitätsmedizin Berlin
    • Contact: Claudia Spies, MD. Prof.; Phone Number: +49 30 450 55 11 02; Email: claudia.spies@charite.de
    • Principal Investigator: Claudia Spies, MD, Prof.
    • Sub-Investigator: Nicolas Paul, MD, Prof.
    • Sub-Investigator: Björn Weiß, MD, Prof.
    • Sub-Investigator: Désirée Boehnke, MD
    • Sub-Investigator: Claudia Denke
    • Sub-Investigator: Frédéric Schwarz

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: No

• Sampling Method: Probability Sample

Study Population

Intensive Care unit patients, who were invited for follow-up care by the PICS outpatient clinic of the Department of Anesthesiology and Intensive Care Medicine (CCM/CVK)

Description

Inclusion Criteria:

• Patients who, between January 1, 2021, and December 31, 2025:
• were invited for follow-up care by the PICS outpatient clinic of the Department of Anesthesiology and Intensive Care Medicine (CCM/CVK)
• were ≥18 years old at the time of the appointment.

Exclusion Criteria:

• none

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort
Intensive care unit patients; Intensive care unit patients, which are invited in the post-intensive care outpatient clinic

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Follow-up appointment	Participation in the first scheduled follow-up appointment at the post-intensive care syndrome (PICS) outpatient clinic (binary: attended vs. did not attend) is measured by medical record review.	01.01.2021- 31.12.2025

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Cancellation of a scheduled follow-up appointment.	Cancellation of a scheduled follow-up appointment is measured by medical record review.	01.01.2021- 31.12.2025
Reasons for canceling a scheduled appointment.	Reasons for canceling a scheduled appointment is measured by medical record review.	01.01.2021- 31.12.2025
Failure to attend a scheduled follow-up appointment.	Failure to attend a scheduled follow-up appointment is measured by medical record review.	01.01.2021- 31.12.2025
Death after discharge from the intensive care unit until the first follow-up appointment.	Death after discharge from the intensive care unit until the first follow-up appointment is measured by medical record review.	01.01.2021- 31.12.2025
Death between the first and second follow-up appointments.	Death between the first and second follow-up appointments is measured by medical record review.	01.01.2021- 31.12.2025
Scheduling a second follow-up appointment after initial presentation at the outpatient clinic.	Scheduling a second follow-up appointment after initial presentation at the outpatient clinic is measured by medical record review.	01.01.2021- 31.12.2025
Attendance at the second scheduled follow-up appointment after initial presentation at the outpatient clinic.	Attendance at the second scheduled follow-up appointment after initial presentation at the outpatient clinic is measured by medical record review.	01.01.2021- 31.12.2025
Scheduling a third follow-up appointment after initial presentation at the outpatient clinic.	Scheduling a third follow-up appointment after initial presentation at the outpatient clinic is is measured by medical record review.	01.01.2021- 31.12.2025
Attendance at the third scheduled follow-up appointment after initial presentation at the outpatient clinic.	Attendance at the third scheduled follow-up appointment after initial presentation at the outpatient clinic is measured by medical record review.	01.01.2021- 31.12.2025

Collaborators and Investigators

• Sponsor: Charite University, Berlin, Germany
• Investigators: Study Director: Claudia Spies, MD, Prof., Charite University, Berlin, Germany

Study record dates

Study Major Dates

• Study Start (Actual): February 10, 2026
• Primary Completion (Estimated): February 1, 2027
• Study Completion (Estimated): February 1, 2027

Study Registration Dates

• First Submitted: January 19, 2026
• First Submitted That Met QC Criteria: January 19, 2026
• First Posted (Actual): January 28, 2026

Study Record Updates

• Last Update Posted (Actual): February 12, 2026
• Last Update Submitted That Met QC Criteria: February 10, 2026
• Last Verified: February 1, 2026

More Information

Terms related to this study

• Additional Relevant MeSH Terms: postintensive care syndrome
• Other Study ID Numbers: PICS-CARE

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No