Multigene Germline Panel Testing in Gastric Cancer Patients in Portugal

January 27, 2026 updated by: Beatriz Mourato, Unidade Local De Saúde Do Norte Alentejano
Multigene germeline panel test in gastric cancer patients

Study Overview

Status

Completed

Conditions

Detailed Description

We conducted a retrospective observational study including 51 patients with histologically confirmed gastric cancer who underwent MGPT between 2020 and 2025. Genetic testing was performed using validated 15 or 30 gene panels. Clinical, pathological, and survival data were retrieved from medical records.

Study Type

Observational

Enrollment (Actual)

51

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Portugal
      • Portalegre, Portugal
        • Unidade Local de Saúde do Alto Alentejo

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Sampling Method

Non-Probability Sample

Study Population

Adults (≥18 years) with histologically confirmed gastric adenocarcinoma who underwent MGPT between 2020 and 2025

Description

Inclusion Criteria

  • Eligible participants were adults (≥18 years) with histologically confirmed gastric adenocarcinoma who underwent MGPT between 2020 and 2025;
  • Ability to understand Portuguese and/or English;
  • Ability to provide valid informed consent.

Exclusion Criteria:

  • All patients who met eligibility and inclusion criteria were included in the study;
  • Patients without a definitive genetic report or with incomplete clinical data for key study variables were excluded.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
MGPT result
Time Frame: 5 years
positive vs negative
5 years

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Unidade Local De Saúde Do Norte Alentejano

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

September 20, 2023

Primary Completion (Actual)

August 1, 2025

Study Completion (Actual)

September 1, 2025

Study Registration Dates

First Submitted

October 1, 2025

First Submitted That Met QC Criteria

January 27, 2026

First Posted (Actual)

February 4, 2026

Study Record Updates

Last Update Posted (Actual)

February 4, 2026

Last Update Submitted That Met QC Criteria

January 27, 2026

Last Verified

January 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • MGPT Gastric Cancer (Other Identifier: 1)

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

YES

IPD Sharing Supporting Information Type

  • STUDY_PROTOCOL

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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