Effect of CBCT Dose Reduction on the Mandibular Canal Visibility Compared to Standard CBCT Dose Diagnostic Accuracy Study

February 24, 2026 updated by: Mai Mostafa Mosaad Shaldoum, Cairo University
The goal of this observational study is to evaluate the diagnostic accuracy of CBCT dose reduction on the mandibular canal visibility, and their effect on canal cortication compared to standard CBCT dose as a gold standard. The main question it aims to answer is: Will the lower CBCT doses affect the visualization of mandibular canal when compared to standard CBCT dose as a gold standard?

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Actual)

20

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Egypt
      • Cairo, Egypt
        • Cairo University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult
  • Older Adult

Accepts Healthy Volunteers

N/A

Sampling Method

Non-Probability Sample

Study Population

Dry human mandibles that will be recruited from Anatomy Department, Faculty of Medicine, Cairo University.

Description

Inclusion Criteria:

  • sound mandibles

Exclusion Criteria:

  • fractured mandibles

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
I1: Conventional dose CBCT imaging

exposure parameters:

  • Kilovoltage: 90 kVp.
  • Milliampere: 8 mA.
  • Exposure time: 13.5s
  • Voxel size: 0.4 mm
Diagnostic test: CBCT imaging
Each dry human mandible will be scanned 6 times (3 conventional CBCT protocols and 3 Ultra-low CBCT protocols)
I2: Conventional dose CBCT imaging

exposure parameters:

  • Kilovoltage: 90 kVp.
  • Milliampere: 5.6 mA.
  • Exposure time: 9 s
  • Voxel size: 0.6 mm
Diagnostic test: CBCT imaging
Each dry human mandible will be scanned 6 times (3 conventional CBCT protocols and 3 Ultra-low CBCT protocols)
I3: CBCT imaging with Ultra low dose

exposure parameters:

  • Kilovoltage: 90 kVp.
  • Milliampere: 7.1 mA.
  • Exposure time: 6 s
  • Voxel size: 0.2 mm
Diagnostic test: CBCT imaging
Each dry human mandible will be scanned 6 times (3 conventional CBCT protocols and 3 Ultra-low CBCT protocols)
I4: CBCT imaging with Ultra low dose

exposure parameters:

  • Kilovoltage: 90 kVp.
  • Milliampere: 5.6 mA.
  • Exposure time: 4.5s
  • Voxel size: 0.4 mm.
Diagnostic test: CBCT imaging
Each dry human mandible will be scanned 6 times (3 conventional CBCT protocols and 3 Ultra-low CBCT protocols)
I5: CBCT imaging with Ultra low dose

exposure parameters:

  • Kilovoltage: 90 kVp.
  • Milliampere: 2.2 mA.
  • Exposure time: 4.5 s
  • Voxel size: 0.6 mm.
Diagnostic test: CBCT imaging
Each dry human mandible will be scanned 6 times (3 conventional CBCT protocols and 3 Ultra-low CBCT protocols)
R (Reference standard): CBCT imaging with standard dose

exposure parameters:

  • Kilovoltage: 90 kVp.
  • Milliampere: 10 mA.
  • Exposure time: 18s
  • Voxel size: 0.2 mm.
Diagnostic test: CBCT imaging
Each dry human mandible will be scanned 6 times (3 conventional CBCT protocols and 3 Ultra-low CBCT protocols)

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Primary outcome Evaluation of the diagnostic accuracy of the lowest CBCT dose (Milliampere: 2.2 mA.) compared to the gold standard CBCT dose (Milliampere: 10 mA.) on the mandibular canal visibility.
Time Frame: March 2024
March 2024

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Cairo University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 4, 2023

Primary Completion (Actual)

March 23, 2024

Study Completion (Actual)

May 20, 2024

Study Registration Dates

First Submitted

February 24, 2026

First Submitted That Met QC Criteria

February 24, 2026

First Posted (Actual)

March 2, 2026

Study Record Updates

Last Update Posted (Actual)

March 2, 2026

Last Update Submitted That Met QC Criteria

February 24, 2026

Last Verified

February 1, 2026

More Information

Terms related to this study

Other Study ID Numbers

  • ORAD 711

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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