Propofol Versus Sevoflurane Anesthesia on the Intraocular Pressure and Hemodynamics in Patient Undergoing Cyclophotocoagulation (cyclophotocoag)

March 25, 2026 updated by: Waleed Adel Ahmed, Sohag University

Comparative Study Between the Effects of Propofol Versus Sevoflurane Anesthesia on the Intraocular Pressure and Hemodynamics in Patient Undergoing Cyclophotocoagulation (Cpc )Operation

we use two different technique of anaesthesia for anaesthesia of patient undergoining CPC operation (20 each) were comparable with regard to demographic data and hemodynamic variables, IOP. After approval by our local Ethics Committee and written informed consent, 40 ASA physical status I, II or III patients scheduled for elective CBC operations were included in this study group s anasthetized with sevofluran while group p anaesthetized with propofol with repeated measurment of intraocular pressure of the other eye to detect which method better for IOP.

Study Overview

Status

Not yet recruiting

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Estimated)

40

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

  • Egypt
    • Sohag Governorate
      • Sohag, Sohag Governorate, Egypt
        • Suhag faculty of medicine

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

ASA I to III

Exclusion Criteria:

  • known allergies; adverse reactions to any of the anesthetic agents used in the study
  • unstable angina or manifest congestive heart failure.
  • airway management was expected to be difficult

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Supportive Care
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: group P patient anaesthetized by propofol
glaucoma patient anaesthetized by propofol in induction and maintenance with fentanyl and cisatracurium as muscle relaxant during cyclophotocoagulation operation
Drug: Propofol and Fentanyl administration
Group P patient anaesthetized by propofol and fentanyle for induction and maintenance
Active Comparator: Grpoup S patient anesthetized by sevoflurane
glaucoma patient anaesthetized by Sevoflurane in induction and maintenance with fentanyl and cisatracurium as muscle relaxant during cyclophotocoagulation operation
Drug: Sevoflurane and fentanyl administration
Group S patient anaesthetized by sevoflurane and fentanyl for induction and maintenance

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
measurement of Intra ocular pressure during different type of anesthesia
Time Frame: 2 minute after administration of muscle relaxant and every 5 minute until termination of surgery
2 minute after administration of muscle relaxant and every 5 minute until termination of surgery

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Sohag University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

March 1, 2026

Primary Completion (Estimated)

June 10, 2026

Study Completion (Estimated)

July 20, 2026

Study Registration Dates

First Submitted

February 25, 2026

First Submitted That Met QC Criteria

February 25, 2026

First Posted (Actual)

March 3, 2026

Study Record Updates

Last Update Posted (Actual)

March 27, 2026

Last Update Submitted That Met QC Criteria

March 25, 2026

Last Verified

March 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • soh-med-25-9----2PD

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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