Is There a Benefit From Addition of Physical Exercise to Diet Restriction/Limitation in PCOS Women With Asthma?

February 26, 2026 updated by: Ali Mohamed Ali ismail, Cairo University
Women with polysyctic ovarian syndrome (PCOS) usually develop many complications including asthma. Nowdays, diet restriction combimed with phsyical exercises may improve both problems

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Detailed Description

Forty Women with asthma with PCOS will be enrolled to be catogrized to Group I or group II. Group I will enroll twenty females with PCOS and asthma who will apply forty minutes walking on treadmill three times per week. Also Group I will follow low calorie diet and daily metformin for 12 weeks. Group II will will enroll twenty females with PCOS and asthma who will follow low calorie diet and daily metformin for 12 weeks

Study Type

Interventional

Enrollment (Estimated)

40

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Contact Backup

Study Locations

  • Egypt
    • Dokki
      • Giza, Dokki, Egypt
        • Recruiting
        • Cairo University
        • Contact:

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • PCOS women
  • women with asthma
  • obese women (calss I)

Exclusion Criteria:

  • cardiac problems
  • renal problems
  • liver problems

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: group number 1
Group I will enroll twenty females with PCOS and asthma who will apply forty minutes walking on treadmill three times per week. Also Group I will follow low calorie diet and daily metformin for 12 weeks.
Behavioral: exercise plus limiitng diet
Group I will enroll twenty females with PCOS and asthma who will apply forty minutes walking on treadmill three times per week. Also Group I will follow low calorie diet and daily metformin for 12 weeks.
Active Comparator: group number 2
Group II will will enroll twenty females with PCOS and asthma who will follow low calorie diet and daily metformin for 12 weeks
Behavioral: limiting diet
Group II will will enroll twenty females with PCOS and asthma who will follow low calorie diet and daily metformin for 12 weeks

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
forced vital capcity
Time Frame: it will be measured after 12 weeks
it is a pulmonary function testing
it will be measured after 12 weeks

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
forced expiratory volume
Time Frame: It will be measured after 12 weeks
it is a pulmonary function testing at the first second of expiration
It will be measured after 12 weeks
forced expiratory volume to forced expiratory capcity
Time Frame: It will be measured after 12 weeks
it is a common ratio test in pulmonary function examiantions
It will be measured after 12 weeks
body mass index
Time Frame: It will be measured after 12 weeks
it will be assessed on empty stomach and bladder
It will be measured after 12 weeks
waist circumference
Time Frame: it will be measured after 12 weeks
it will be assessed at level of patient umblicus
it will be measured after 12 weeks
waist hip ratio
Time Frame: It will be measured after 12 weeks
it is a measure of excess weight
It will be measured after 12 weeks
Mini asthma quality of life questionnaire
Time Frame: It will be measured after 12 weeks
it is a questioanire assessing life quality in asthma
It will be measured after 12 weeks
scale of fatigue severity
Time Frame: It will be measured after 12 weeks
it is a questionaire assesing fatigue
It will be measured after 12 weeks
luteinizing-hormone to follicle-stimulating-hormone ratio
Time Frame: It will be measured after 12 weeks
it is an indicator on level of sex hormone production
It will be measured after 12 weeks
Testosterone
Time Frame: It will be measured after 12 weeks
it is androgen hormone
It will be measured after 12 weeks
Dehydroepiandrosterone
Time Frame: It will be measured after 12 weeks
it is a hormone that body naturally produces in the adrenal gland
It will be measured after 12 weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Cairo University

Investigators

  • Principal Investigator: Ali MA Ismail, lecturer, Cairo University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

February 7, 2026

Primary Completion (Estimated)

June 30, 2026

Study Completion (Estimated)

July 15, 2026

Study Registration Dates

First Submitted

February 26, 2026

First Submitted That Met QC Criteria

February 26, 2026

First Posted (Actual)

March 3, 2026

Study Record Updates

Last Update Posted (Actual)

March 3, 2026

Last Update Submitted That Met QC Criteria

February 26, 2026

Last Verified

February 1, 2026

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • IRB000-14233-69

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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