Lung Mechanics and Ventilation Efficiency in Robotic Surgery

March 8, 2026 updated by: Betül Güven, Ankara City Hospital Bilkent

Phase-Specific Evaluation of Lung Mechanics and Ventilation Efficiency During Robotic Surgery: A Prospective Observational Cohort Study

Robotic surgery requires pneumoperitoneum and specific surgical positioning such as steep Trendelenburg, reverse Trendelenburg, or supine positioning. These intraoperative conditions may lead to cranial displacement of the diaphragm, reduced lung compliance, and increased airway pressures, potentially impairing respiratory mechanics and gas exchange.

Previous studies have primarily evaluated respiratory mechanics during robotic surgery at single time points or within specific surgical procedures. However, dynamic changes occurring during critical phases of robotic surgery have rarely been evaluated prospectively.

This prospective observational cohort study aims to evaluate phase-specific changes in lung mechanics and ventilation efficiency during robotic surgery. Key parameters including mechanical power (MP), ventilation efficiency index (VEI), static compliance, and driving pressure will be analyzed across predefined intraoperative phases.

Study Overview

Status

Not yet recruiting

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Estimated)

65

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

Yes

Sampling Method

Non-Probability Sample

Study Population

Adult patients undergoing robotic surgery under general anesthesia with mechanical ventilation.

Robotic procedures from different surgical specialties such as urology, gynecology, and general surgery will be included.

Description

Inclusion Criteria

  • Age ≥ 18 years
  • Patients undergoing robotic surgery
  • General anesthesia with mechanical ventilation
  • Written informed consent

Exclusion Criteria

  • Severe chronic pulmonary disease
  • Refusal to participate
  • Missing intraoperative ventilatory data

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Robotic Surgery
Adult patients undergoing robotic surgery under general anesthesia with mechanical ventilation. Intraoperative respiratory mechanics and gas exchange parameters will be prospectively recorded during predefined phases of robotic surgery (T0-T4). Parameters include ventilatory settings, airway pressures, arterial blood gas values, and calculated indices such as mechanical power, driving pressure, static compliance, and ventilation efficiency index. The study evaluates phase-specific changes in lung mechanics and ventilation efficiency during robotic surgical procedures.
Other: Intraoperative Mechanical Ventilation Monitoring
Prospective recording of ventilatory parameters and respiratory mechanics during robotic surgery under general anesthesia. Measurements will be obtained at predefined surgical phases (after intubation, pneumoperitoneum initiation, steep Trendelenburg positioning, undocking, and before extubation). Recorded parameters include tidal volume, respiratory rate, peak airway pressure, plateau pressure, positive end-expiratory pressure, arterial blood gas measurements, and calculated indices such as mechanical power, driving pressure, static compliance, and ventilation efficiency index.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Ventilation Efficiency Index (VEI) change across robotic surgery phases
Time Frame: Intraoperative (T0-T4)
Evaluation of VEI changes between predefined intraoperative phases.
Intraoperative (T0-T4)

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Mechanical Power Change
Time Frame: intraoperative
Evaluation of mechanical power changes across surgical phases.
intraoperative
Static Lung Compliance Change
Time Frame: intraoperative
Evaluation of static compliance changes during robotic surgery.
intraoperative

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Ankara City Hospital Bilkent

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

March 20, 2026

Primary Completion (Estimated)

April 1, 2026

Study Completion (Estimated)

June 30, 2026

Study Registration Dates

First Submitted

March 8, 2026

First Submitted That Met QC Criteria

March 8, 2026

First Posted (Actual)

March 12, 2026

Study Record Updates

Last Update Posted (Actual)

March 12, 2026

Last Update Submitted That Met QC Criteria

March 8, 2026

Last Verified

March 1, 2026

More Information

Terms related to this study

Other Study ID Numbers

  • TABED1-26-2262

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

UNDECIDED

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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