Arthroscopic ACL Reconstruction: Quadriceps Tendon vs Hamstring Tendon Autograft - A Prospective RCT

March 10, 2026 updated by: Sahil Jangra, Sawai Mansingh Medical College

Prospective Comparative Study on Functional Outcome of Arthroscopic Reconstruction of Anterior Cruciate Ligament Using Quadriceps Tendon Graft Versus Hamstrings Graft

A prospective randomized controlled trial comparing functional outcomes of arthroscopic anterior cruciate ligament reconstruction using quadriceps tendon autograft versus hamstring tendon autograft at SMS Medical College, Jaipur. Outcomes assessed using IKDC score, Lysholm score, and clinical stability tests at pre-operative, 3-month, and 6-month intervals.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

70

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • India
    • Rajasthan
      • Jaipur, Rajasthan, India, 302004
        • Sawai Man Singh Medical College and Associated Hospitals

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • Grade 3 ACL tear confirmed on MRI • Age 15-55 years • Medically fit for surgery • Willing and able to complete 6-month follow-up

Exclusion Criteria:

  • • Multi-ligament knee injury • Complex meniscal tears requiring additional procedures • Intra-articular fractures • Pre-existing osteoarthritis • Inability to attend follow-up

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: Group A - Quadriceps Tendon Autograft
Arthroscopic ACL reconstruction using partial-thickness quadriceps tendon autograft without bone block
Procedure: Arthroscopic ACL Reconstruction
Arthroscopic ACL reconstruction under tourniquet control using interference screw fixation
Active Comparator: Group B - Hamstring Tendon Autograft
Arthroscopic ACL reconstruction using semitendinosus and gracilis tendon autograft
Procedure: Arthroscopic ACL Reconstruction
Arthroscopic ACL reconstruction under tourniquet control using interference screw fixation

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
IKDC Subjective Knee Evaluation Score
Time Frame: Pre-operative, 3 months, and 6 months post-surgery
Patient-reported functional outcome score (0-100, higher = better)
Pre-operative, 3 months, and 6 months post-surgery
Lysholm Knee Scoring Scale
Time Frame: Pre-operative, 3 months, and 6 months post-surgery
Knee function scoring scale (0-100, higher = better)
Pre-operative, 3 months, and 6 months post-surgery

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Lachman Test
Time Frame: Pre-operative, 3 months, and 6 months post-surgery
Clinical test for anterior tibial translation at 30° knee flexion (positive/negative)
Pre-operative, 3 months, and 6 months post-surgery
Anterior Drawer Test
Time Frame: Pre-operative, 3 months, and 6 months post-surgery
Clinical test for anterior tibial translation at 90° knee flexion (positive/negative)
Pre-operative, 3 months, and 6 months post-surgery
Pivot Shift Test
Time Frame: Pre-operative, 3 months, and 6 months post-surgery
Clinical test for rotational knee instability (positive/negative)
Pre-operative, 3 months, and 6 months post-surgery

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Sawai Mansingh Medical College

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 1, 2023

Primary Completion (Actual)

May 31, 2024

Study Completion (Actual)

May 31, 2024

Study Registration Dates

First Submitted

March 10, 2026

First Submitted That Met QC Criteria

March 10, 2026

First Posted (Actual)

March 13, 2026

Study Record Updates

Last Update Posted (Actual)

March 13, 2026

Last Update Submitted That Met QC Criteria

March 10, 2026

Last Verified

March 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • SMSMC/ORTHO/ACL/2023
  • IEC SMS Medical College Jaipur (Other Identifier: SMS Medical College Jaipur)

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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