- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT07493733
MPTA on Full Standing and Rosenberg Views in Patients Undergoing High Tibial Osteotomy
Comparing Medial Proximal Tibial Angle Measurements on Full-leg Standing Radiographs and The Rosenberg View in Patients Undergoing High Tibial Osteotomy
Study Overview
Status
Conditions
Intervention / Treatment
Detailed Description
The medial open wedge high tibial osteotomy (MOW-HTO) is awidely and successfully performed treatment for medial compartment osteoarthritis (OA) of the knee joint .
The primary goal of MOW-HTO is to alleviate mechanical stress onthe medial compartment of the knee joint by shifting the weight-bearing line (WBL) toward the lateral compartment .
Correct alignment is essential for achieving long-term success and favorable outcomes, making accurate preoperative planning crucial.
Accepted gold standard for preoperative coronal plane assessment of lower limb alignment are full-leg standing radiographs (FLSR) .
Measurement variables in the coronal plane include the mechanical lateral proximal femoral angle (mLPFA), mechanical lateral distal femoral angle (mLDFA), mechanical medial proximal tibial angle and mechanical lateral distal tibial angle.
However, alignment measurements are influenced by factors such as knee flexion, rotation, and loading conditions .
Identifying these factors prior to surgery is crucial to minimizing the risk of surgical error.
Posteroanterior weight-bearing radiographs taken with the knee in 45 degrees of flexion, commonly referred to as the Rosenberg view (RB), are routinely used preoperatively . This imaging technique not only facilitates the assessment of the severity of knee OA but also aids in evaluating the degree of soft tissue laxity contributing to varus alignment-a factor increasingly recognized for its clinical significance .
For knowledge, one study has investigated how knee alignment parameters used for planning of HTO differ when measured using the RB .
The invistegator hypothesize that the medial proximal tibial angle (MPTA) does not differ when measured on RB radiographs compared with FLSR. Being a widely accessible and commonly used imaging technique, if confirmed, this finding would suggest that the RB could serve as a com-plementary modality for preoperative planning for MOW-HTO.
Study Type
Enrollment (Estimated)
Contacts and Locations
Study Contact
- Name: Ahmed Gadelkarem Farrag, Resident Doctor
- Phone Number: +20 01009372187
- Email: agad6126@gmail.com
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
- Adult
- Older Adult
Accepts Healthy Volunteers
Sampling Method
Study Population
Description
Inclusion Criteria:
- All patients were screened for medial compartment OA of either the left or right knee joint.
- Availability of preoperative full-length standing radiograph and Rosenberg view.
- Completeness of patient records .
- Patient consent
Exclusion Criteria:
- Insufficient patient records .
- Previous ligamentous surgery or osteotomies .
- Known neuromuscular or metabolic disorder .
- Absence of a radiographic reference ball.
Study Plan
How is the study designed?
Design Details
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
|---|---|
|
Difference in medial proximal tibial angle (MPTA) measurments in both the Rosenberg view and full-leg standing radiographic position
Time Frame: Baseline
|
Baseline
|
Collaborators and Investigators
Sponsor
Publications and helpful links
General Publications
- Ogata K, Yoshii I, Kawamura H, Miura H, Arizono T, Sugioka Y. Standing radiographs cannot determine the correction in high tibial osteotomy. J Bone Joint Surg Br. 1991 Nov;73(6):927-31. doi: 10.1302/0301-620X.73B6.1955438.
- [9] Deep K, Eachempati KK, Apsingi S. The dynamic nature of alignment and variations in normal knees. Bone Joint Lett J 2015;97-B(4):498-502. https://doi.org/ 10.1302/0301-620X.97B4.33740.
- Palmer J, Getgood A, Lobenhoffer P, Nakamura R, Monk P. Medial opening wedge high tibial osteotomy for the treatment of medial unicompartmental knee osteoarthritis: A state-of-the-art review. J ISAKOS. 2024 Feb;9(1):39-52. doi: 10.1016/j.jisako.2023.10.004. Epub 2023 Oct 13.
- [7] Dugdale TW, Noyes FR, Styer D. Preoperative planning for high tibial osteotomy. The effect of lateral tibiofemoral separation and tibiofemoral length. Clin Orthop Relat Res 1992;274:248-64.
- [6] Yasuda K, Majima T, Tsuchida T, Kaneda K. A ten- to 15-year follow-up observation of high tibial osteotomy in medial compartment osteoarthrosis. Clin Orthop Relat Res 1992;282:186-95.
- [5] Hernigou P, Medevielle D, Debeyre J, Goutallier D. Proximal tibial osteotomy for osteoarthritis with varus deformity. A ten to thirteen-year follow-up study. J Bone Joint Surg Am 1987;69(3):332-54.
- Coventry MB, Ilstrup DM, Wallrichs SL. Proximal tibial osteotomy. A critical long-term study of eighty-seven cases. J Bone Joint Surg Am. 1993 Feb;75(2):196-201. doi: 10.2106/00004623-199302000-00006.
- COVENTRY MB. OSTEOTOMY OF THE UPPER PORTION OF THE TIBIA FOR DEGENERATIVE ARTHRITIS OF THE KNEE. A PRELIMINARY REPORT. J Bone Joint Surg Am. 1965 Jul;47:984-90. No abstract available.
- [1] Ayet CAB, Mancino F, Lim YP, Qian K, Jacob G, Parker DA. Satisfactory 10-year survivorship of medial opening wedge high tibial osteotomy for isolated medial compartment osteoarthritis and varus alignment: an analysis from a high-volume institution. Knee Surg Sports Traumatol Arthrosc 2025 May;33(5):1804-14. https://doi.org/10.1002/ksa.12633. Published online February 20.
- Gkekas NK, Komnos GA, Mylonas T, Chalatsis G, Koutalos AA, Hantes ME. Medial open wedge high tibial osteotomy is a viable option in young patients with advanced arthritis in a long-term follow-up. Knee Surg Sports Traumatol Arthrosc. 2025 Mar;33(3):1025-1032. doi: 10.1002/ksa.12469. Epub 2024 Sep 18.
Study record dates
Study Major Dates
Study Start (Estimated)
Primary Completion (Estimated)
Study Completion (Estimated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- Comparison of MPTA in two view
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
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