The Relationship Between Early Motor Repertoire Quality and Later-term Motor Function in Children With CP

Cerebral palsy (CP) is a group of disorders attributed to non-progressive disorders occurring in the developing fetal, infantile brain, affecting posture, movement development, and activity limitations. It occurs in approximately 2 to 2.5 per 1,000 live births. The prognosis for gross motor function among children with CP is extremely variable. This variability poses a significant challenge to scientific definitions of motor function for clinicians who regularly deal with practical issues such as examination, prognosis, intervention planning, and outcome assessment in children with CP. Observing the general quality of movement of preterm or term babies can be used to identify babies at risk of developing neurological disorders and can provide information about possible future motor function.

Study Overview

• Status: Completed
• Conditions: Cerebral Palsy

Detailed Description

They frequently use the 66-item Gross Motor Function Measurement (GMFM-66) to evaluate gross functions and the Gross Motor Function Classification System (GMFCS) to classify gross motor functions. It is important to use the data obtained from these methods to assist in examination, prognosis, intervention planning and outcome evaluation for children with CP. In addition, the Motor Optimality Score (MOS), which is based on observing the quantity and quality of movement patterns, is used. When we look at the literature, there are very few studies comparing the amount and quality of the motor repertoire obtained using the early motor optimality score with the motor functions in the later period. Therefore, in this study, in addition to evaluating general movements in early infancy (3-5 months), it is aimed to predict the motor function in the future by evaluating the quality and amount of motor repertoire (motor optimality score, MOS) (movement and posture of the baby).

• Study Type: Observational
• Enrollment (Actual): 40

Contacts and Locations

Study Locations

• Turkey (Türkiye)
  • Ataşehir
    • Istanbul, Ataşehir, Turkey (Türkiye), 34750
      • Türkiye Spastik Çocuklar Vakfı

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child
• Accepts Healthy Volunteers: Yes

• Sampling Method: Probability Sample

Study Population

Children diagnosed with Cerebral Palsy who applied to the Turkish Spastic Children Foundation for evaluation between 2011 and 2023 and whose Prechtl Analysis shots were archived between the 10th and 20th weeks will be included in the study.

Description

Inclusion Criteria:

• Children with a diagnosis of Cerebral Palsy
• Children who applied to the Turkish Spastic Children Foundation between 2011-2023
• Availability of Prechtl General Movements Assessment recordings obtained between 10-20 weeks post-term age
• Availability of GMFM-66 assessment data

Exclusion Criteria:

• Lack of parental or legal guardian consent
• Presence of additional diagnoses affecting motor assessment
• Cases where GMFM-66 evaluation was not applicable
• Incomplete clinical records

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort

1; Babies aged between 3 months and 5 months (corrected age) who applied to the Turkish Spastic Children Foundation for risky baby evaluation between 2011 and 2023, whose videos were recorded for GM's evaluation, and who were later diagnosed with cerebral palsy will be included in the study. The quality of the early engine repertoire will be evaluated with MOS (Motor Optimality Score) based on GM's video footage. The evaluation will be carried out by a physiotherapist who has received advanced GM's evaluation training.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Motor Optimality Score (MOS)	Motor optimality score (MOS) have 5 categories to the score. These are fidgety movements (max 12 points), repertoire of co-existent other movements (max 4 points), quality of other movements (max 4 points), posture (max 4 points) and movement character (max 4 points). The category scores are added to a max of 28 points.	3 months
Gross Motor Function Measurement (GMFM-66)	The Gross Motor Function Measure (GMFM) is a tool that has been developed to assess change in gross motor function in children with cerebral palsy aged 5 months to 16 years of age.1 The GMFM measures 'activity' as defined within the Interna- tional Classification of Functioning, Disability and Health.2 To administer the GMFM, a trained therapist observes the child completing a number of gross motor tasks in a standardised environment, and the child's best ability is measured.	3 months

Collaborators and Investigators

• Sponsor: Uskudar University
• Investigators: Principal Investigator: osman çoban, phd, Uskudar University

Study record dates

Study Major Dates

• Study Start (Actual): December 1, 2023
• Primary Completion (Actual): January 30, 2024
• Study Completion (Actual): January 30, 2024

Study Registration Dates

• First Submitted: March 23, 2026
• First Submitted That Met QC Criteria: March 23, 2026
• First Posted (Actual): March 27, 2026

Study Record Updates

• Last Update Posted (Actual): March 30, 2026
• Last Update Submitted That Met QC Criteria: March 26, 2026
• Last Verified: March 1, 2026

More Information

Terms related to this study

• Keywords: cerebral palsy; Gross Motor Function; EARLY MOTOR REPERTOIRE QUALITY; LATER-TERM MOTOR FUNCTION
• Additional Relevant MeSH Terms: Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Brain Damage, Chronic; Cerebral Palsy
• Other Study ID Numbers: Uskudaraysesav

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: UNDECIDED
• IPD Plan Description: After we complete the study, results will be shared

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No