Factors Predicting The Success of Ejaculation Sparing Transurethral Resection of Prostate in Benign Prostatic Hyperplasia Patients

April 2, 2026 updated by: Ain Shams University
evaluate the factors predicting the success of ejaculation-sparing TURP in patients with BPH after surgery, in terms of voiding improvement and preserved ejaculation post-operatively.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

108

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Egypt
    • Cairo Governorate
      • Cairo, Cairo Governorate, Egypt, 11566
        • AinShams University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • sexually active male patient with normal ejaculatory function
  • upper urinary tract affection and renal insufficiency.
  • Chronic Urinary Retention
  • Patients with failed medical therapy.
  • Patients not compliant to medical treatment
  • Patients with recurrent hematuria or recurrent lower urinary tract infections

Exclusion Criteria:

  • Patients with an anterior urethral stricture
  • Patients with history of urethral operations
  • Patients with previous prostatic surgery
  • Patients with neurological disorders
  • Non sexually active patients

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Prevention
  • Allocation: N/A
  • Interventional Model: Single Group Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: patients with BPH underwent Ejaculatory preserving TURP
Procedure: ejaculatory preserving TURP

In our study, we performed an EP-TURP technique, which is adopted in our institute and involves the preservation of 1 cm of urethral mucosa all around the verumontanum, including the prostatic apical urethral mucosa, with adequate resection of the prostatic adenoma, including the apical prostatic tissue, which was resected lateral to the spared urethral mucosa to ensure adequate management of the outflow obstruction. (8). Bi-polar TURP was performed using a 26 Fr. Resectoscope (Karl Storz, Tuttlingen, Germany) and Karl Storz- AUTOCON® IV.

Intraoperative cystoscopic evaluation and documentation of the prostatic anatomy were done. SML was measured cystoscopically using a 22 Fr sheath with centimeter markings. Operative time, perioperative complications, catheterization duration, and hospital stay were recorded. Urethral catheter removal was planned after 24-48 hours unless prolonged catheterization was clinically indicated.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Preservation of antegrade ejaculation at 3 months
Time Frame: 3 months
The primary outcome was to assess the post operative ejaculation at 3 months using Male Sexual Health Questionnaire for ejaculatory dysfunction short form (MSHQ-Ej.D-SF).
3 months

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
post-operative post-voiding residual volume
Time Frame: 3 months
Measurement of post-operative post-voiding residual volume by Pelvi-abdominal Ultrasound
3 months

Other Outcome Measures

Outcome Measure
Measure Description
Time Frame
post operative complication
Time Frame: 3 months
assess post operative complications using Clavien-Dindo classification for TURP
3 months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Ain Shams University

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

  • 2. Tawfik AM, Alloussi S, Ben Rhouma S. (2017). Ejaculation-Sparing Techniques in TURP for Benign Prostatic Hyperplasia: A Systematic Review and Meta-analysis. Journal of Urology; 197(4): 1050-1057.

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

April 12, 2025

Primary Completion (Actual)

December 12, 2025

Study Completion (Actual)

January 25, 2026

Study Registration Dates

First Submitted

February 12, 2026

First Submitted That Met QC Criteria

April 2, 2026

First Posted (Actual)

April 7, 2026

Study Record Updates

Last Update Posted (Actual)

April 7, 2026

Last Update Submitted That Met QC Criteria

April 2, 2026

Last Verified

April 1, 2026

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • FMASU MS 397/2025

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

YES

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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