Conservative Management of Placenta Accreta Spectrum Using Kasr Al-Ainy Technique With or Without Hayman Sutures

April 2, 2026 updated by: Abdalla Mousa, Cairo University
This study evaluates whether adding Hayman sutures in the conservative Management of Placenta Accreta Spectrum Using Kasr Al-Ainy Technique reduces intraoperative blood loss and improves outcomes

Study Overview

Status

Not yet recruiting

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Estimated)

48

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Contact Backup

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • Age 18-40 years
  • Antenatal PAS diagnosis confirmed by TAS/TVS/Doppler
  • Eligible for conservative Kasr Al-Ainy surgery
  • Singleton pregnancy
  • Written informed consent

Exclusion Criteria:

  • Multiple pregnancy
  • Uterine fibroids
  • Previous cesarean myomectomy
  • Cervical accreta
  • Extensive parametrial or bladder invasion requiring hysterectomy
  • Known coagulopathy or uncorrected bleeding disorder.
  • Severe medical comorbidities rendering the patient unfit for major surgery under general anesthesia (e.g., severe cardiac or pulmonary disease)
  • Medical disorders as HTN and DM
  • Patient refusal

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Double

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: Kasr Al-Ainy Technique Alone
Procedure: Kasr Al-Ainy Technique Alone
  1. Vascular Ligation: Bilateral uterine artery tying at high and low levels.
  2. Compression Sutures: Anterior and posterior cervicovaginal stitches for hemostasis.
  3. Segmental Resection: Excision of invaded myometrium and placental tissue.
  4. Dual-Layer Repair: Myometrial approximation followed by reinforcing imbricating sutures.
  5. Final Hemostasis: Confirmation of bleeding control prior to abdominal closure.
Experimental: Kasr Al-Ainy Technique + Hayman Sutures
Procedure: Kasr Al-Ainy Technique + Hayman Sutures
  1. Vascular Ligation: Bilateral uterine artery tying at high and low levels.
  2. Compression Sutures: Anterior and posterior cervicovaginal stitches for hemostasis.
  3. Segmental Resection: Excision of invaded myometrium and placental tissue.
  4. Dual-Layer Repair: Myometrial approximation followed by reinforcing imbricating sutures.
  5. Final Hemostasis: Confirmation of bleeding control prior to abdominal closure.
  6. Application of Hayman vertical compression sutures

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Intra-operative estimated blood loss
Time Frame: During operation
During operation

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Cairo University

Investigators

  • Principal Investigator: Emad Salah, M.D., Cairo University
  • Principal Investigator: Mona Sedik, M.D., Cairo University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

April 5, 2026

Primary Completion (Estimated)

December 31, 2026

Study Completion (Estimated)

December 31, 2026

Study Registration Dates

First Submitted

April 2, 2026

First Submitted That Met QC Criteria

April 2, 2026

First Posted (Actual)

April 9, 2026

Study Record Updates

Last Update Posted (Actual)

April 9, 2026

Last Update Submitted That Met QC Criteria

April 2, 2026

Last Verified

April 1, 2026

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • MS-636-2025

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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