Early Loading for Implants With Calcium Titanate Surface Technology in Posterior Mandibular Bone

April 18, 2026 updated by: Alexandria University

Feasibility of Early Loading for Implants With Calcium Titanate Surface Technology in Posterior Mandibular Bone

Dental implants have revolutionized oral rehabilitation for partially edentulous patients. Recent advances in implant design and surface treatments have prompted the investigation of early loading methods, which aim to minimize treatment time while maintaining success rates.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

22

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Egypt
    • Azarita
      • Alexandria, Azarita, Egypt, 00203
        • Outpatient Clinic of Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Alexandria University, Egypt

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • Adequate bone volume allowing implant placement without grafting (width > 6 mm, height > 10 mm)
  • bone quality classified as D2

Exclusion Criteria:

  • uncontrolled systemic diseases
  • active infection or untreated periodontal disease
  • heavy smoking (>10 cigarettes/day)
  • parafunctional habits
  • inability to attend follow-up visits

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: Conventional
Other: Delayed loading
Conventional Delayed Loading at 24 weeks, the definitive restoration was delivered using standard prosthetic procedures.
Experimental: Test Group
Other: Early implant loading
Early Loading at 4 weeks, a screw-retained definitive restoration was delivered using standard prosthetic procedures.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Change in implant stability
Time Frame: baseline, 2 ,4 ,12 ,24 weeks
Ostell device was used for implant stability assessment.
baseline, 2 ,4 ,12 ,24 weeks

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Change in bone gain
Time Frame: 12 and 24-weeks
amount of marginal bone resorption measured mesially and distally from the implant-abutment junction to the first bone-to-implant contact using digital image analysis software
12 and 24-weeks
Change in density
Time Frame: 12 and 24-weeks
CBCT is used for bone density assessmnet
12 and 24-weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Alexandria University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

December 1, 2024

Primary Completion (Actual)

June 28, 2025

Study Completion (Actual)

June 28, 2025

Study Registration Dates

First Submitted

April 18, 2026

First Submitted That Met QC Criteria

April 18, 2026

First Posted (Actual)

April 24, 2026

Study Record Updates

Last Update Posted (Actual)

April 24, 2026

Last Update Submitted That Met QC Criteria

April 18, 2026

Last Verified

April 1, 2026

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 1043_03/2025

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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