Effect of Physical Therapy Rehabilitation on Gait and Plantar Pressure in Patients After Total Knee Replacement

April 21, 2026 updated by: Hadeel Saad Alsirhani, Jouf University

Effect of Physical Therapy Rehabilitation on Gait Temporospatial Parameters and Plantar Pressure Distribution in Patients Following Total Knee Replacement Surgery

This study aims to investigate the effects of a structured physical therapy and rehabilitation program on gait temporospatial parameters and plantar pressure distribution in patients who have undergone total knee replacement surgery.

Patients undergoing total knee replacement often experience alterations in gait patterns and weight distribution, which may affect functional mobility and recovery outcomes. This study will evaluate whether a targeted rehabilitation program can improve walking performance and restore more symmetrical plantar pressure distribution.

Participants will be assessed before and after the intervention using objective gait analysis and plantar pressure measurement tools. The findings of this study may help improve rehabilitation strategies and enhance functional recovery following knee replacement surgery.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Estimated)

30

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

  • Saudi Arabia
      • Sakakah, Saudi Arabia, 72388
        • Recruiting
        • Jouf University and Prince Mutaib Bin Abdulaziz Hospital- Sakaka, AlJouf in Saudi Arabia
        • Contact:

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • Female participants aged between 40 and 70 years
  • Patients who have undergone unilateral total knee replacement (TKR) or have knee pathology without surgical intervention
  • Ability to walk independently with or without assistive devices
  • Medically stable and able to participate in a physical therapy rehabilitation program

Exclusion Criteria:

  • Neurological disorders affecting gait (e.g., stroke, Parkinson's disease)
  • Severe musculoskeletal disorders other than knee pathology
  • History of revision knee replacement surgery
  • Significant cognitive impairment affecting the ability to follow instructions
  • Any contraindications to physical therapy rehabilitation

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Non-Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Post-TKR Group
Other: Physical Therapy Rehabilitation
A structured physical therapy rehabilitation program including range of motion exercises, muscle strengthening, balance training, and gait training aimed at improving functional mobility and gait performance.
Experimental: Non-Surgical Group
Other: Physical Therapy Rehabilitation
A structured physical therapy rehabilitation program including range of motion exercises, muscle strengthening, balance training, and gait training aimed at improving functional mobility and gait performance.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Cadence (steps/minute) measured using gait analysis system
Time Frame: Baseline and after completion of the rehabilitation program (e.g., 6-10 weeks)
Cadence will be measured using a gait analysis system. The average number of steps per minute will be calculated for each participant.
Baseline and after completion of the rehabilitation program (e.g., 6-10 weeks)
Peak pressure
Time Frame: Baseline and after completion of the rehabilitation program (e.g., 6-10 weeks)
kPa
Baseline and after completion of the rehabilitation program (e.g., 6-10 weeks)
Postural Alignment
Time Frame: Baseline and after completion of the rehabilitation program (e.g., 6-10 weeks)
The REEDCO Posture Sheet
Baseline and after completion of the rehabilitation program (e.g., 6-10 weeks)
Quadriceps Muscle Strength (MMT score 0-5)
Time Frame: Baseline and after completion of the rehabilitation program (e.g., 6-10 weeks)
Muscle strength will be assessed using Manual Muscle Testing (MMT) graded from 0 to 5.
Baseline and after completion of the rehabilitation program (e.g., 6-10 weeks)
Circular measurement of quadriceps (cm)
Time Frame: Baseline and after completion of the rehabilitation program (e.g., 6-10 weeks)
To evaluate the degree of muscle wasting (atrophy), hypertrophy, or the degree of oedema and joint swelling
Baseline and after completion of the rehabilitation program (e.g., 6-10 weeks)
Walking speed (velocity)
Time Frame: Baseline and after completion of the rehabilitation program (e.g., 6-10 weeks)
m/sec
Baseline and after completion of the rehabilitation program (e.g., 6-10 weeks)
Step and Stride time
Time Frame: Baseline and after completion of the rehabilitation program (e.g., 6-10 weeks)
Seconds
Baseline and after completion of the rehabilitation program (e.g., 6-10 weeks)
Step and Stride length
Time Frame: Baseline and after completion of the rehabilitation program (e.g., 6-10 weeks)
cm
Baseline and after completion of the rehabilitation program (e.g., 6-10 weeks)
Toe In/Out
Time Frame: Baseline and after completion of the rehabilitation program (e.g., 6-10 weeks)
Degree
Baseline and after completion of the rehabilitation program (e.g., 6-10 weeks)
Base Of Support (BOS)
Time Frame: Baseline and after completion of the rehabilitation program (e.g., 6-10 weeks)
cm
Baseline and after completion of the rehabilitation program (e.g., 6-10 weeks)
Average Pressure
Time Frame: Baseline and after completion of the rehabilitation program (e.g., 6-10 weeks)
kPa
Baseline and after completion of the rehabilitation program (e.g., 6-10 weeks)
Gradient Pressure
Time Frame: Baseline and after completion of the rehabilitation program (e.g., 6-10 weeks)
kPa
Baseline and after completion of the rehabilitation program (e.g., 6-10 weeks)
Hamstring Muscle Strength (MMT score 0-5)
Time Frame: Baseline and after completion of the rehabilitation program (e.g., 6-10 weeks)
Muscle strength will be assessed using Manual Muscle Testing (MMT) graded from 0 to 5.
Baseline and after completion of the rehabilitation program (e.g., 6-10 weeks)

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Jouf University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

August 15, 2025

Primary Completion (Estimated)

December 30, 2027

Study Completion (Estimated)

December 30, 2027

Study Registration Dates

First Submitted

April 14, 2026

First Submitted That Met QC Criteria

April 21, 2026

First Posted (Actual)

April 29, 2026

Study Record Updates

Last Update Posted (Actual)

April 29, 2026

Last Update Submitted That Met QC Criteria

April 21, 2026

Last Verified

April 1, 2026

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • TKR-Gait-PT01

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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