Optimal Antiplatelet Therapy for Chinese Patients With Coronary Artery Disease

Optimal Antiplatelet Therapy for Chinese Patients With Coronary Artery Disease

Patrocinadores

Patrocinador principal: Shenyang Northern Hospital

Colaborador: Guangdong Provincial People's Hospital

Fuente Shenyang Northern Hospital
Resumen breve

Antiplatelet therapy is the cornerstone for the prevention of atherothrombosis in patients with coronary artery disease (CAD). However, the efficacy and safety of antiplatelet therapy are varied due to ethnic and/or individual variability. The aim of the OPT-CAD study was to demonstrate contemporary status and outcomes of antiplatelet therapy in Chinese CAD patients, and to explore predictors of ischemic or bleeding events in such cohort.Patients above 18 years old who were diagnosed as CAD and received antiplatelet therapy were prospectively enrolled in this national wide, non-intervention registry. All medications and laboratory tests were physician discretion.

Descripción detallada

Antiplatelet therapy is the cornerstone for the prevention of atherothrombosis in patients with coronary artery disease (CAD). However, the efficacy and safety of antiplatelet therapy are varied due to ethnic and/or individual variability. The aim of the OPT-CAD study was to demonstrate contemporary status and outcomes of antiplatelet therapy in Chinese CAD patients, and to explore predictors of ischemic or bleeding events in such cohort.Patients above 18 years who were diagnosed as CAD and received antiplatelet therapy were prospectively enrolled in this national wide, non-intervention registry. All medications and laboratory tests were at physician discretion.

Estado general Completed
Fecha de inicio November 2012
Fecha de Terminación March 2015
Fecha de finalización primaria December 2014
Tipo de estudio Observational
Resultado primario
Medida Periodo de tiempo
Major adverse cardiac and cerebral events 12month
Resultado secundario
Medida Periodo de tiempo
all cause death 12month
Stent thrombosis 12 month
rehospitalization 12 month
any bleeding events 12 month
recurrent angina 12 month
myocardial infarction 12 months
stroke 12 months
any revascularization 12 months
Inscripción 14032
Condición
Elegibilidad

Método de muestreo: Non-Probability Sample

Criterios:

Inclusion criteria:

1. Clinical diagnosis of coronary heart disease

2. Age >= 18 years old

3. receiving any antiplatelet agents

4. Informed written consent signed

Exclusion Criteria:

1. With severe disease and life expectancy for 6 months or less

2. Difficult to attain follow-up situations judged by researchers (travel, speech or mental disorder, etc.)

3. Taking part in an interventional clinical research

Género: All

Edad mínima: 18 Years

Edad máxima: 85 Years

Voluntarios Saludables: No

Oficial general
Apellido Papel Afiliación
Yaling Han, MD Principal Investigator Shenyang Military Region General Hospital
Ubicación
Instalaciones:
The first affiliated hospital of Bengbu Medical College | Bengbu, Anhui, China
Beijing Anzhen Hospital | Beijing, Beijing, China
Navy General Hospital | Beijing, Beijing, China
The 304th Hospital of PLA | Beijing, Beijing, China
The 306th of PLA | Beijing, Beijing, China
The Luhe teaching hospital of the Capital Medical University | Beijing, Beijing, China
The People's Hospital of Beijing University | Beijing, Beijing, China
Yanshan hospital | Beijing, Beijing, China
Beijing Fuwai Hospital | Beijin, Beijing, China
Third Military Medical University Xinqiao Hospital | Chongqing, Chongqing, China
The 174th Hospital of PLA | Xiamen, Fujian, China
Lanzhou military region general hospital | Lanzhou, Gansu, China
The First Affiliated Hospital of Guangzhou Medical College | Guangdong, Guangdong, China
General hospital of armed police foreces in Guangzhou | Guangzhou, Guangdong, China
Guangdong General Hospital | Guangzhou, Guangdong, China
Guangzhou Baiyun district hospital | Guangzhou, Guangdong, China
Guangzhou military region general hospital | Guangzhou, Guangdong, China
Guangzhou Panyu district central hospital | Guangzhou, Guangdong, China
Liwan District People's Hospital of Guangzhou | Guangzhou, Guangdong, China
The first hospital of Guangzhou | Guangzhou, Guangdong, China
Shenzhen Longgang center hospital | Shenzhen, Guangdong, China
Zhuhai people's hospital | Zhuhai, Guangdong, China
The 3rd people's hospital of Nanning | Nanning, Guangxi, China
Guizhou provincial people's hospital | Guiyang, Guizhou, China
The 425th of PLA | Sanya, Hainan, China
Affiliated hospital of Hebei University of Engineering | Handan, Hebei, China
The people's hospital of Rongcheng | Rongcheng, Hebei, China
Bethune International Peace Hospital | Shijiazhuang, Hebei, China
The People's Hospital of Tangxian | Tangxian, Hebei, China
The 251st of PLA | Zhangjiakou, Hebei, China
Daqing oil field hospital | Daqing, Heilongjiang, China
Heilongjiang provincial hospital | Harbin, Heilongjiang, China
The 211st of PLA | Harbin, Heilongjiang, China
The third affiliated hospital of Qiqihar Medical University | Qiqihar, Heilongjiang, China
The People's Hospital of Hebi | Hebi, Henan, China
The 152nd Hospital of PLA | Pingdingshan, Henan, China
The People's Hospital of Zhecheng County | Zhecheng, Henan, China
The First Hospital of Organization Directly Under Henan Province | Zhengzhou, Henan, China
Wuhan Asia heart hospital | Wuhan, Hubei, China
The first hospital of Changshan | Changshan, Hunan, China
The general hospital of Xilingol League | Holingol, Inner Mongolia, China
The first hospital of Nanjing | Nanjing, Jiangsu, China
The central hospital of Nantong | Nantong, Jiangsu, China
The Affiliated Hospital of Jinggangshan University | Ji'an, Jiangxi, China
Central Hospital of Changchun | Changchun, Jilin, China
The affiliated hospital to Changchun University of Chinese Medicine | Changchun, Jilin, China
The China-Japan union hospital of Jilin University | Changchun, Jilin, China
The First Affiliated Hospital of Jilin University | Changchun, Jilin, China
The Second Affiliated Hospital of Jilin University | Changchun, Jilin, China
The 222nd of PLA | Jilin, Jilin, China
Meihekou central hospital | Meihekou, Jilin, China
Siping first people's hospital | Siping, Jilin, China
The 206th of PLA | Tonghua, Jilin, China
The people's hospital of Tonghua | Tonghua, Jilin, China
Tonghua central hospital | Tonghua, Jilin, China
Anshan central hospital | Anshan, Liaoning, China
Anshan hospital affiliated of China Medical University | Anshan, Liaoning, China
The first affiliated hospital of Liaoning Medical University | Anshan, Liaoning, China
The people's hospital of Xiuyan | Anshan, Liaoning, China
The third hospital of Anshan | Anshan, Liaoning, China
Dalian municipal central hospital affiliated of Dalian Medical University | Dalian, Liaoning, China
The 210th Hospital of PLA | Dalian, Liaoning, China
Zhongshan Hospital Affiliated to Dalian University | Dalian, Liaoning, China
The 230th of PLA | Dandong, Liaoning, China
The people's hospital of Dandong | Dandong, Liaoning, China
Central Hospital affiliated to Shenyang Medical College | Fengtian, Liaoning, China
Fushun central hospital | Fushun, Liaoning, China
The 7th hospital of China Medical University | Fushun, Liaoning, China
The Second Affiliated and gynecology and obstetirs hospital of Fuxin city | Fuxin, Liaoning, China
The people's hospital of Haicheng | Haicheng, Liaoning, China
The 205th of PLA | Jinzhou, Liaoning, China
The third affiliated hospital of Liaoning medical College | Jinzhou, Liaoning, China
Central hospital of Liaoyang | Liaoyang, Liaoning, China
Liaoyang Chemical General Hospital | Liaoyang, Liaoning, China
The 201th Hospital of PLA | Liaoyang, Liaoning, China
The 2nd people's hospital of Liaoyang | Liaoyang, Liaoning, China
Jinqiu Hospital | Shenyang, Liaoning, China
Liaoning northern hospital | Shenyang, Liaoning, China
Shenyang the forth hospital of people | Shenyang, Liaoning, China
The 202nd Hospital of PLA | Shenyang, Liaoning, China
The 242nd of PLA | Shenyang, Liaoning, China
The 245th of PLA | Shenyang, Liaoning, China
The 463rd Hospital of PLA | Shenyang, Liaoning, China
The First Affiliated Hospital of Liaoning University of Traditional Chinese Medicine | Shenyang, Liaoning, China
The first people's hospital of Shenyang | Shenyang, Liaoning, China
The Forth affiliated hospital of Liaoning University of Traditional Chinese Medicine | Shenyang, Liaoning, China
The Second Affiliated Hospital of Shenyang Medical College | Shenyang, Liaoning, China
The Third Affiliated Hospital of Shenyang Medical College | Shenyang, Liaoning, China
Traditional Chinese Medicine hospital of Shenyang | Shenyang, Liaoning, China
Yingkou Development Zone Hospital | Yingkou, Liaoning, China
General hospital of Ningxia Medical University | Yinchuan, Ningxia, China
The people's hospital of Huzhu | Huzhu, Qinghai, China
Tangdu hospital | Xi'an, Shaanxi, China
Jinan military general hospital | Jinan, Shandong, China
Jiaozhou central hospital | Qingdao, Shandong, China
Wanjie Hospital | Zibo, Shandong, China
Eastern hospital in Shanghai | Shanghai, Shanghai, China
Yuncheng central hospital | Yuncheng, Shanxi, China
Sichuan military general hospital | Chengdu, Sichuan, China
Armed police foreces'hospital of Tianjin | Tianjin, Tianjin, China
The 254th of PLA | Tianjin, Tianjin, China
Xizang military general hospital | Lasa, Tibet, China
The 11st of PLA | Ili, Xinjiang, China
General hospital of Wulumuqi | Urumqi, Xinjiang, China
The Chest Hospital of Xinjiang Uyghur Autonomous Region | Urumqi, Xinjiang, China
The 4th public hospital of Honghe | Honghe, Yunnan, China
Hangzhou first people's hospital | Hangzhou, Zhejiang, China
Ubicacion Paises

China

Fecha de verificación

December 2015

Fiesta responsable

Tipo: Principal Investigator

Afiliación del investigador: Shenyang Northern Hospital

Nombre completo del investigador: Han Yaling

Título del investigador: Dr

Palabras clave
Tiene acceso ampliado No
Condición Examinar
Grupo de brazo

Etiqueta: Antiplatelet therapy

Descripción: patients with coronary artery disease receiving any antiplatelet therapy, without any intervention by the investigators.

Acrónimo OPT-CAD
Información de diseño del estudio

Modelo de observación: Cohort

Perspectiva de tiempo: Prospective

Fuente: ClinicalTrials.gov