- ICH GCP
- Registro de ensayos clínicos de EE. UU.
- Ensayo clínico NCT05352438
Manual Therapy and Splint Therapy in Patients With Temporomandibular Dysfunction
Investigation of the Effectiveness of Manual Therapy and Splint Therapy in Patients With Myofascial Temporomandibular Dysfunction Combined With Bruxism
Descripción general del estudio
Estado
Condiciones
Intervención / Tratamiento
Descripción detallada
A total of 56 patients were evaluated. Among those, 20 patients who did not meet the criteria were excluded. 36 patients met the inclusion criteria and were willing to participate in the study.
The patients were randomly separated into two groups using the method of single- and double-digit numbers written on paper in a sealed envelope.
Those who selected a double-digit number were assigned to the manual therapy (MT) group (n:18) and those with a single-digit number to the splint therapy (ST) group (n:18).
After the further exclusion of 7 patients during the treatment period, the final evaluations were compared of 29 patients (15 MT and 14 ST) who completed the 4-week treatment process.
Tipo de estudio
Inscripción (Actual)
Fase
- No aplica
Contactos y Ubicaciones
Ubicaciones de estudio
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Kahramanmaraş, Pavo
- Türkoğlu Dr. Kemal Beyazıt State Hospital
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Criterios de participación
Criterio de elegibilidad
Edades elegibles para estudiar
Acepta Voluntarios Saludables
Géneros elegibles para el estudio
Descripción
Inclusion Criteria:
- Ages between 18 and 50 years old,
- Patients with a diagnosis of myofascial TMD with Bruxism according to the diagnostic criteria for temporomandibular disorders (DC/TMD),
- Having pain severity ≥3 according to the Visual analogue scale (VAS),
- Probable sleep bruxism according to clinical evaluation and a questionnaire-based assessment.
Exclusion Criteria:
- Patients with a diagnosis other than myofascial TMD according to the research DC/TMD,
- a history of surgery associated with cervical and/or TMJ problems,
- a proven specific pathological condition such as cervical and/or TMJ malignancy, fracture, or systemic rheumatoid disease,
- a history of facial paralysis, a diagnosed psychiatric disease,
- if they were undergoing orthodontic treatment,
- had received physiotherapy within the last 3 months,
- or could not be co-operative.
Plan de estudios
¿Cómo está diseñado el estudio?
Detalles de diseño
- Propósito principal: Tratamiento
- Asignación: Aleatorizado
- Modelo Intervencionista: Asignación paralela
- Enmascaramiento: Único
Armas e Intervenciones
Grupo de participantes/brazo |
Intervención / Tratamiento |
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Experimental: Manual Therapy Group
Manual Therapy combined with education and home exercises
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Patient education directed at parafunctional behaviors was given, and an exercise program was taught, with all the patients instructed to perform these exercises at home. The home exercise program included diaphragmatic breathing exercises, chin-tuck exercises, mandibular resistance exercises, and neck muscle stretching exercises. The patients were instructed to perform the exercises as 3 sets of 10 repetitions per day. In addition to the patient education and home exercises, the Manual Therapy group received a manual therapy program applied as 2 sessions of 45 mins each week for 4 weeks (total 8 sessions) by an investigator. Soft tissue and joint mobilizations were applied to the TMJ and surrounding structures and to cervical segments, trigger point treatment was applied to trigger points, and myofascial loosening was performed. Patients were instructed to perform the exercises learned in the home exercise program in 3 sets of 10 repetitions every day. |
Experimental: Splint Therapy Group
Splint Therapy combined with education and home exercises
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Patient education directed at parafunctional behaviors was given, and an exercise program was taught, with all the patients instructed to perform these exercises at home. The home exercise program included diaphragmatic breathing exercises, chin-tuck exercises, mandibular resistance exercises, and neck muscle stretching exercises. The patients were instructed to perform the exercises as 3 sets of 10 repetitions per day. In addition to the patient education and home exercises, the Splint Therapy group was given a static occlusal splint, and adjustments were made as necessary. All the patients in this group were instructed to use the splint when sleeping for a period of one month. |
¿Qué mide el estudio?
Medidas de resultado primarias
Medida de resultado |
Medida Descripción |
Periodo de tiempo |
---|---|---|
Change from Baseline in Pain severity at 4 weeks
Periodo de tiempo: Baseline, 4 weeks
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Pain severity was measured with a Visual Analogue Scale (VAS), marked from 0 to 10, where 0 indicates no pain and 10 indicates intolerable pain.
The patients were instructed to mark the scale corresponding to the severity of pain felt.
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Baseline, 4 weeks
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Change frim Baseline in Fatigue severity at 4 weeks
Periodo de tiempo: Baseline, 4 weeks
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Fatigue level was measured with the Fatigue Severity Scale, where patients were asked to indicate their levels of agreement with a 0-7 scale indicating "0" strong disagreement and "7" strong agreement at a total of 9 questions.
A sum of all responses was calculated for analysis.
Sixty-three was the maximum score.
The higher value represented a higher level of fatigue.
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Baseline, 4 weeks
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Change from Baseline in Sleep quality at 4 weeks
Periodo de tiempo: Baseline, 4 weeks
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The sleep quality of patients was analyzed with the Pittsburgh Sleep Quality Index (PSQI).
The PSQI includes 24 items related to both daytime and nocturnal sleep.
The responses were scored from 0-3, as 7 subscores to give a global score of total points in the range of 0-21.
A score of ≥5 indicated poor sleep quality.
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Baseline, 4 weeks
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Change from Baseline in Jaw Function limitation at 4 weeks
Periodo de tiempo: Baseline, 4 weeks
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Jaw function limitation was measured by the Jaw Functional Limitation Scale-20 (JFLS-20) where the patients asked for from 1 to 10 points per item (higher scores indicate worse jaw function).
The JFLS-20 has 3 subscales: Mastication (6 items), Vertical Jaw Mobility (4 items), and Emotional and Verbal Expression (10 items).
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Baseline, 4 weeks
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Change from Baseline in Neck Disability at 4 weeks
Periodo de tiempo: Baseline, 4 weeks
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Neck Disability Index, consists of 10 items.
Individuals included in the study were asked to give a score between 0 (no disability) and 5 (complete disability) for each item.
The total score varies between 0 (no disability) and 50 (complete disability).
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Baseline, 4 weeks
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Change from Baseline in Patient Satisfaction questionnaire at 4 weeks.
Periodo de tiempo: Baseline, 4 weeks
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The Patient Satisfaction questionnaire was used to assess the patient's satisfaction with the treatment received.
The patient satisfaction questionnaire (PSQ) contains 18 items tapping each of the seven dimensions of satisfaction with medical care measured by the PSQ-18.
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Baseline, 4 weeks
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Change from Baseline in Headache severity at 4 weeks
Periodo de tiempo: Baseline, 4 weeks
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The Headache Impact Test-6 (HIT-6) was used to assess the headache.
The 6-item scale evaluates the frequency, the degree of restriction to daily life and social life, and changes in the mood.
The total score of 50-59 reflects the important impact, and scores ≥60 indicate severe impact.
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Baseline, 4 weeks
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Medidas de resultado secundarias
Medida de resultado |
Medida Descripción |
Periodo de tiempo |
---|---|---|
Change from Baseline in Head Posture at 4 weeks
Periodo de tiempo: Baseline, 4 weeks
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Head posture is defined as the craniovertebral angle.
It is the angle formed by the intersection of a horizontal line along the spinous process of C7 and the line drawn towards the ear tragus.
A craniovertebral angle of <48-50° is accepted as an anterior tilt of the head.
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Baseline, 4 weeks
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Change from Baseline in Cervical Range of Motion at 4 weeks
Periodo de tiempo: Baseline, 4 weeks
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A goniometer was used to measure the cervical region's range of motion (ROM).
Cervical region flexion, extension, right-left lateral flexion, and right-left rotation degrees were measured and recorded.
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Baseline, 4 weeks
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Change from Baseline in Temporomandibular Joint Range of Motion at 4 weeks
Periodo de tiempo: Baseline, 4 weeks
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For maximal mouth opening, the distance between the upper and lower incisors was measured and recorded.
For protrusion, the distance between the lower and upper incisors was measured horizontally by asking the patient to bring the lower jaw forward as far as possible while the posterior teeth were in contact with each other.
For right and left lateral shifts, the distance between the upper and lower incisors was measured by asking the patient to slide it to the right and left separately as much as possible.
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Baseline, 4 weeks
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Change from Baseline in Trigger points at 4 weeks
Periodo de tiempo: Baseline, 4 weeks
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While the participants were in the supine position the masseter, temporalis, pyterigoideus lateralis, pyterigoideus medialis, and digastric muscles were evaluated.
In the sitting position, the sternoclavicular, suboccipital, and upper trapezius muscles were palpated, and the trigger points in these muscles and their number were evaluated.
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Baseline, 4 weeks
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Colaboradores e Investigadores
Patrocinador
Investigadores
- Director de estudio: Aysenur Tuncer, Hasan Kalyoncu University
Fechas de registro del estudio
Fechas importantes del estudio
Inicio del estudio (Actual)
Finalización primaria (Actual)
Finalización del estudio (Actual)
Fechas de registro del estudio
Enviado por primera vez
Primero enviado que cumplió con los criterios de control de calidad
Publicado por primera vez (Actual)
Actualizaciones de registros de estudio
Última actualización publicada (Actual)
Última actualización enviada que cumplió con los criterios de control de calidad
Última verificación
Más información
Términos relacionados con este estudio
Palabras clave
Términos MeSH relevantes adicionales
- Enfermedades Articulares
- Enfermedades musculoesqueléticas
- Enfermedades Musculares
- Enfermedades Estomatognáticas
- Enfermedades de los dientes
- Enfermedades de la mandíbula
- Trastornos Craneomandibulares
- Enfermedades mandibulares
- Síndromes de dolor miofascial
- Bruxismo
- Trastornos de la articulación temporomandibular
- Síndrome de disfunción de la articulación temporomandibular
Otros números de identificación del estudio
- 2019-67
Información sobre medicamentos y dispositivos, documentos del estudio
Estudia un producto farmacéutico regulado por la FDA de EE. UU.
Estudia un producto de dispositivo regulado por la FDA de EE. UU.
Esta información se obtuvo directamente del sitio web clinicaltrials.gov sin cambios. Si tiene alguna solicitud para cambiar, eliminar o actualizar los detalles de su estudio, comuníquese con register@clinicaltrials.gov. Tan pronto como se implemente un cambio en clinicaltrials.gov, también se actualizará automáticamente en nuestro sitio web. .
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