Hypertension Management in Young Adults Personalised by Echocardiography and Clinical Outcome. (HyperEcho)
調査の概要
詳細な説明
HyperEcho is a multi-centre longitudinal observational study, to investigate whether baseline transthoracic echocardiography along with routine data collected in the hypertension clinic can guide clinicians to better manage, and improve risk stratification for cardiovascular disease in young adults with hypertension. Participants are characterised as hypertensive patients aged between 18 to 40 years old and referred to the hypertension clinic to manage their blood pressure. A patient and public involvement exercise has been performed to ensure this study design would appeal to patients attending the hypertension clinic, and to investigate the preferred method of contact.
The study visit will be carried out during the planned routine visit of the participants to the hypertension clinics of NHS trusts within England. Routine data will be collected by the assigned nurse for the hypertension clinic as part of the clinical service, and research participation will not affect the clinical progress of the participant. The additional research component to the clinic will be asking the participants for their consent to undergo a research echocardiography scan if it has not been a part of their clinical assessment. Participants will also be asked to consent to the use of their data that has been collected in the hypertension clinic, such as; referral letters, medical history, 24-hour blood pressure monitoring report, ECG, blood samples, body fat composition, and dietary questionnaire. In addition to this, participants will be asked to consent to further review of their data and medical notes during their follow up visits (up to 10 years).
Previous young adult patients who visited the Hypertension clinics in the last 10 years will be also recruited. This cohort will be asked to consent to allow the research team to collect and use their clinical data as well as follow up their medical notes. They will not actively participate in the study as they will not require visiting the hypertension clinic or undergoing an echocardiography scan.
研究の種類
入学 (予想される)
段階
- 適用できない
連絡先と場所
研究連絡先
- 名前：Maryam Alsharqi
- 電話番号：+44(0)1865 572832
- メール：maryam.alsharqi@cardiov.ox.ac.uk
研究場所
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Oxford、イギリス、OX3 9DU
- 募集
- Cardiovascular Clinical Research Facility
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コンタクト：
- Maryam Alsharqi
- 電話番号：+44(0)1865 572832
- メール：maryam.alsharqi@cardiov.ox.ac.uk
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参加基準
適格基準
就学可能な年齢
健康ボランティアの受け入れ
受講資格のある性別
説明
Inclusion Criteria:
- Participant is willing and able to give informed consent for participation in the study.
- Male or Female, aged 18 - 40 years (at the time of their appointment at the hypertension clinic).
- Referred for a Hypertension Clinic in England.
Exclusion Criteria:
- Unable or unwilling to give valid consent for participation in the study.
研究計画
研究はどのように設計されていますか？
デザインの詳細
- 主な目的：診断
- 割り当て：非ランダム化
- 介入モデル：並列代入
- マスキング：4倍
武器と介入
参加者グループ / アーム |
介入・治療 |
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アクティブコンパレータ：Prospective participants
250 participants will be recruited prospectively during the hypertension clinic, where a full set of data will be collected from each participant as part of their standard hypertension clinical service.
An additional echocardiography scan will be performed for this cohort by the study team, if the scan has not been performed as a part of the clinical care service
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Non-invasive ultrasound imaging of the heart.
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介入なし：Retrospective participants
500 participants will be recruited retrospectively, and no additional echocardiography scan will be required for them.
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この研究は何を測定していますか？
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
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Identification of patient clusters based on echocardiographic and clinical findings
時間枠：Obtained at the first clinical visit
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Number of hypertension patient clusters based on echocardiographic and clinical findings
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Obtained at the first clinical visit
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協力者と研究者
スポンサー
研究記録日
主要日程の研究
研究開始 (実際)
一次修了 (予想される)
研究の完了 (予想される)
試験登録日
最初に提出
QC基準を満たした最初の提出物
最初の投稿 (実際)
学習記録の更新
投稿された最後の更新 (実際)
QC基準を満たした最後の更新が送信されました
最終確認日
詳しくは
この情報は、Web サイト clinicaltrials.gov から変更なしで直接取得したものです。研究の詳細を変更、削除、または更新するリクエストがある場合は、register@clinicaltrials.gov。 までご連絡ください。 clinicaltrials.gov に変更が加えられるとすぐに、ウェブサイトでも自動的に更新されます。
Echocardiography scanの臨床試験
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Centre hospitalier de l'Université de Montréal...Allergan募集
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Helse Nord-Trøndelag HFNorwegian University of Science and Technology; St. Olavs Hospital完了