- ICH GCP
- US Clinical Trials Registry
- Klinisk utprøving NCT01736774
Exercise and Manipulative Therapy for Older Persons With Headache
26. januar 2016 oppdatert av: Sureeporn Uthaikhup, Chiang Mai University
A Randomized Controlled Trial of Exercise and Manipulative Therapy for Older Persons With Frequent Intermittent Headaches Associated With Neck Pain and Impairment
The presence of cervical musculoskeletal impairment is not specific to cervicogenic headache but other various frequent intermittent headache types (i.e.
migraine and tension-type headache) in the elderly population.
There has been no trial to date which has investigated the effectiveness of physiotherapy treatment specifically for older persons with various types of headache with associated neck pain and cervical musculoskeletal impairment.
Thus, the purpose of study investigate the efficacy of physiotherapy treatment for older persons who have headache concomitant with neck pain and musculoskeletal impairment
Studieoversikt
Status
Fullført
Forhold
Intervensjon / Behandling
Detaljert beskrivelse
Headache is a common health problem that affects quality of life in an older population and imposes substantial economic costs.
Headache changes with age.
Features of headache become less typical and neck pain is more frequently associated with headache in older persons.
We recently demonstrated that the presence of cervical musculoskeletal impairment is not specific to cervicogenic headache (headache caused by the neck).
Rather it was present in various frequent intermittent headache types in elders when compared to elders without headache.
Changes in headache characteristics with age play an important role not only in diagnosis but also in treatment choice.
Impairment in cervical musculoskeletal function found in older persons with headache has implications for headache management choices as the evidence indicates that physiotherapy management methods such as manual therapy and therapeutic exercise are an effective management approach for headache associated with the neck.
Physiotherapy treatment would be a safe therapeutic option and may have a beneficial effect for elders with headache who have neck pain and concomitant cervical musculoskeletal dysfunction.
This is particularly relevant as there are widespread concerns about medication overuse, adverse drug events and drug interactions in older persons.
The effective management of older persons with headache in particular of those with atypical features of headache remains a challenge.
Physiotherapy is indicated in those older persons diagnosed with cervicogenic headache but could also be adjunct treatment for those with cervical musculoskeletal signs who are suspected of having transitional headache.
At present, there has been no trial to date which has investigated the effectiveness of physiotherapy treatment specifically for older persons with various types of headache with associated neck pain and cervical musculoskeletal impairment.
A clinical trial of treatment of cervical musculoskeletal impairment in older persons with various headache types may help guide management of headache in attempts to lesson medication use and cost in this population.
Physiotherapy management may be a worthy treatment option particularly in older persons with headache who do not respond well to medication.
Studietype
Intervensjonell
Registrering (Faktiske)
65
Fase
- Ikke aktuelt
Kontakter og plasseringer
Denne delen inneholder kontaktinformasjon for de som utfører studien, og informasjon om hvor denne studien blir utført.
Studiesteder
-
-
-
Chiang Mai, Thailand
- Department of Physical Therapy, Faculty of Associated Medical Sciences
-
-
Deltakelseskriterier
Forskere ser etter personer som passer til en bestemt beskrivelse, kalt kvalifikasjonskriterier. Noen eksempler på disse kriteriene er en persons generelle helsetilstand eller tidligere behandlinger.
Kvalifikasjonskriterier
Alder som er kvalifisert for studier
50 år til 75 år (Voksen, Eldre voksen)
Tar imot friske frivillige
Nei
Kjønn som er kvalifisert for studier
Alle
Beskrivelse
Inclusion Criteria:
- Volunteers suffering from frequent intermittent headache (either migraine, tension-type headache or cervicogenic headache) at least one per month over a period of 3 months or longer
- Aged 50 years or older, female or male
- A score of ≥ 3/10 on visual analogue scale (VAS) of neck pain
- Evidence of cervical musculoskeletal impairment: restriction in active range of cervical motion in extension and rotation and join tenderness in at least one of the upper joint as detected by manual palpation
Exclusion Criteria:
- Headache diagnosed as following: temporal arteritis, trigeminal neuralgia, cluster headache, chronic paroxysmal hemicrania/hemicranias continua, temporomandibular joint dysfunction
- Other diagnosed disorders: cerebrovascular disease, Parkinson disease, cognitive disturbance
- Previous history of head or neck surgery
- Lack of willingness to receive either pragmatic treatment or usual care
- Physiotherapy or chiropractic treatment for headache in previous 6 months
Studieplan
Denne delen gir detaljer om studieplanen, inkludert hvordan studien er utformet og hva studien måler.
Hvordan er studiet utformet?
Designdetaljer
- Primært formål: Behandling
- Tildeling: Randomisert
- Intervensjonsmodell: Parallell tildeling
- Masking: Dobbelt
Våpen og intervensjoner
Deltakergruppe / Arm |
Intervensjon / Behandling |
---|---|
Eksperimentell: Usual care intervention
Primary care as required including medication
|
The usual care intervention will include appropriate primary care as required including medication
|
Eksperimentell: Physiotherapy treatment
Exercise and manipulative therapy
|
Exercise and manipulative therapy treatment for 10 weeks:The treatment intervention consists of two visits per week for the first four weeks (8 treatments) and one visit per week for the last six weeks (6 treatments)
|
Hva måler studien?
Primære resultatmål
Resultatmål |
Tiltaksbeskrivelse |
Tidsramme |
---|---|---|
Headache frequency
Tidsramme: Change from baseline in headache frequency at week 11 and 6 months after intervention
|
The number of headache frequency in the past week
|
Change from baseline in headache frequency at week 11 and 6 months after intervention
|
Sekundære resultatmål
Resultatmål |
Tiltaksbeskrivelse |
Tidsramme |
---|---|---|
Headache intensity
Tidsramme: Change from baseline in headache intensity at week 11 and 6 months after intervention
|
An average intensity in the past week will be rated on a 1-10 VAS
|
Change from baseline in headache intensity at week 11 and 6 months after intervention
|
Headache duration
Tidsramme: Change from baseline in headache duration at week 11 and 6 months after intervention
|
The number of hours of headache in the past week
|
Change from baseline in headache duration at week 11 and 6 months after intervention
|
Neck pain intensity
Tidsramme: Change from baseline in neck pain intensity at week 11 and 6 months after intervention
|
Intensity of neck pain will be measured using a 1-10 VAS
|
Change from baseline in neck pain intensity at week 11 and 6 months after intervention
|
Neck pain and disability
Tidsramme: Change from baseline in neck pain and disability at week 11 and 6 months after intervention
|
Neck pain and disability will be measured using neck disability index (NDI-Thai version)
|
Change from baseline in neck pain and disability at week 11 and 6 months after intervention
|
Quality of life
Tidsramme: Change from baseline in quality of life at week 11 and 6 months after intervention
|
The Quality of life will be measured using SF-36 (Thai version)
|
Change from baseline in quality of life at week 11 and 6 months after intervention
|
Medication intake
Tidsramme: Change from baseline in medication intake at week 11 and 6 months after intervention
|
type and dose of all medications taken by subjects will be recorded one week at baseline and prior to follow-up points on a medication diary
|
Change from baseline in medication intake at week 11 and 6 months after intervention
|
Global assessment of treatment benefit
Tidsramme: Changes from baseline in global assessment of treatment benefit at week 11 and 6 months after intervention
|
Patients perceived benefit of treatment will be measured on a scale from 0 (no benefit) to 10 (maximum benefit)
|
Changes from baseline in global assessment of treatment benefit at week 11 and 6 months after intervention
|
Samarbeidspartnere og etterforskere
Det er her du vil finne personer og organisasjoner som er involvert i denne studien.
Sponsor
Etterforskere
- Hovedetterforsker: Sureeporn Uthaikhup, Ph.D., Department of Physical Therapy, Faculty of Associated Medical Sciences
Studierekorddatoer
Disse datoene sporer fremdriften for innsending av studieposter og sammendragsresultater til ClinicalTrials.gov. Studieposter og rapporterte resultater gjennomgås av National Library of Medicine (NLM) for å sikre at de oppfyller spesifikke kvalitetskontrollstandarder før de legges ut på det offentlige nettstedet.
Studer hoveddatoer
Studiestart
1. desember 2012
Primær fullføring (Faktiske)
1. desember 2014
Studiet fullført (Faktiske)
1. juli 2015
Datoer for studieregistrering
Først innsendt
22. november 2012
Først innsendt som oppfylte QC-kriteriene
26. november 2012
Først lagt ut (Anslag)
29. november 2012
Oppdateringer av studieposter
Sist oppdatering lagt ut (Anslag)
28. januar 2016
Siste oppdatering sendt inn som oppfylte QC-kriteriene
26. januar 2016
Sist bekreftet
1. januar 2016
Mer informasjon
Begreper knyttet til denne studien
Nøkkelord
Ytterligere relevante MeSH-vilkår
Andre studie-ID-numre
- MRG5580145
Denne informasjonen ble hentet direkte fra nettstedet clinicaltrials.gov uten noen endringer. Hvis du har noen forespørsler om å endre, fjerne eller oppdatere studiedetaljene dine, vennligst kontakt register@clinicaltrials.gov. Så snart en endring er implementert på clinicaltrials.gov, vil denne også bli oppdatert automatisk på nettstedet vårt. .
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