Symptom Inventory for Gastrointestinal Stromal Tumors
Symptom Burden in Patients With Gastrointestinal Stromal Tumors (GISTs)
The goal of this research study is to better understand the symptoms experienced by patients with GIST.
There are 3 parts to this study. In Part 1, participants will complete 1 set of interviews and questionnaires about GIST symptoms. In Part 2, the importance of some symptoms to patients with GIST will be rated by doctors, nurses, patients, and family caregivers. In Part 3, participants will complete questionnaires about GIST symptoms over 1 year.
You are being asked to take part in Part 3 of the study.
Visão geral do estudo
Status
Condições
Intervenção / Tratamento
Descrição detalhada
Symptom Questionnaires:
If you agree to take part in this study, you will complete questionnaires about symptoms you are having. You will be asked to fill these out 1 time a week during the first 2 months after surgery, 1 time a week during the first 3 months of a new therapy, and every 2 weeks at other times. The questionnaire will ask you to rate how severe your symptoms are and how the symptoms effect the activities of your daily life. The symptom questionnaire should take about 5 minutes to complete. You will complete the questionnaire during the first study visit and at your regular clinic visits.
Between clinic visits, you will be called every 1-2 weeks to complete the questionnaire using an automated telephone system. You can decide what time is most convenient for the automated phone system to call you. If you are not available when the automated system calls, it will call you again at a later time. If you are not reached by the automated phone system after several tries, the study staff will call you. You will be given a secure user name and identification number to use with the automated phone system. The study staff will teach you how to use the automated phone system.
At the clinic visit closest to 3 months after you start the study, you may be seen by a research staff member a second time 1 to 3 days after you completed the symptom questionnaire and asked to fill out the symptom questionnaire again. The research staff member may contact you by phone prior to this clinic visit to arrange times to meet you for the 2 assessments.
Quality-of-Life/Demographic Questionnaires:
At the first visit and the regular clinic visits, you will also rate your overall quality-of-life. This should take about 1 minute to complete.
At the first visit, you will also be asked some demographic questions (such as your age and marital status). Answering these questions should take about 1 minute.
Opinion Questionnaire:
If you are 1 of the first 40 patients enrolled in the study, you will be asked questions about your opinion of the symptom questionnaire at the clinic visit closest to 3 months after you start the study. For example, you will be asked if the symptom questionnaire was easy to understand and complete, and if there were any other questions that should be included. The study staff will use your opinion to decide if changes should be made to the questionnaire or if important symptom questions are missing from the questionnaire. This questionnaire should take about 5 minutes to complete.
Length of Study:
You will be on study for 1 year. You will be off study after you complete the last symptom questionnaire.
This is an investigational study.
Up to 188 participants will take part in this study. Up to 150 participants will be enrolled in Part 3 of this study. All will be enrolled at MD Anderson.
Tipo de estudo
Inscrição (Real)
Contactos e Locais
Locais de estudo
-
-
Texas
-
Houston, Texas, Estados Unidos, 77030
- University of Texas MD Anderson Cancer Center
-
-
Critérios de participação
Critérios de elegibilidade
Idades elegíveis para estudo
Aceita Voluntários Saudáveis
Gêneros Elegíveis para o Estudo
Método de amostragem
População do estudo
Descrição
Inclusion Criteria:
- 18 years of age or older (Patient and family caregiver only)
- Ability to speak and read English (All participants)
- Residing where IVR service is available (Part 3, Patient only)
- Diagnosis of GIST confirmed by pathological analysis (Patient only)
- Starting new treatment (either surgical or medical) and planning to be followed at M.D. Anderson Cancer Center (Part 3, Patient only)
- Written consent to participate (All participants)
- At least 3 months from start of initial treatment (surgical or medical) for GIST (Part 2, Patient only)
- Family caregiver also willing to receive packet for expert panel participation (Part 2, Patient only)
- Physician or nurse with at least 5 years experience caring for patients with GIST (Professional expert only)
- At least one publication in the last 5 years dealing with GIST (Physician professional expert only)
- Identification as a family caregiver by a patient with GIST (Family caregiver only)
- Patient also willing to receive packet for expert panel participation (Family caregiver only)
Exclusion Criteria:
- Medical condition or impaired performance status that would preclude participation in the study (Patient only)
- Diagnosis of active psychosis or severe cognitive impairment as determined by primary physician (Patient only)
- Active treatment (systemic drug therapy or radiation therapy) for a second malignancy (Patient only)
Plano de estudo
Como o estudo é projetado?
Detalhes do projeto
Coortes e Intervenções
Grupo / Coorte |
Intervenção / Tratamento |
|---|---|
|
Part 1
Patient interview and developmental questionnaires
|
10 minutes to complete 3 questionnaires for development of MDASI-GIST
Outros nomes:
Each interview will take approximately 30 minutes.
|
|
Part 2
Content Expert Panel (doctors, nurses) + Patients and Caregivers Questionnaire Development
|
10 minutes to complete 3 questionnaires for development of MDASI-GIST
Outros nomes:
|
|
Part 3
Patient MDASI-GIST Questionnaire
|
Every 4 weeks for one year
Outros nomes:
|
O que o estudo está medindo?
Medidas de resultados primários
Medida de resultado |
Descrição da medida |
Prazo |
|---|---|---|
|
Questionnaire Responses to Symptom Inventory for Gastrointestinal Stromal Tumors
Prazo: Patients will be followed on study for 1 year regardless of changes in disease stage or treatments.
|
Descriptive statistics used to assess the distributional characteristics and demographics of the study population and to report how patients rate symptom severity and interference with function.
|
Patients will be followed on study for 1 year regardless of changes in disease stage or treatments.
|
Colaboradores e Investigadores
Patrocinador
Colaboradores
Investigadores
- Investigador principal: Loretta A. Williams, PhD, MSN, M.D. Anderson Cancer Center
Publicações e links úteis
Datas de registro do estudo
Datas Principais do Estudo
Início do estudo (Real)
Conclusão Primária (Antecipado)
Conclusão do estudo (Antecipado)
Datas de inscrição no estudo
Enviado pela primeira vez
Enviado pela primeira vez que atendeu aos critérios de CQ
Primeira postagem (Estimativa)
Atualizações de registro de estudo
Última Atualização Postada (Real)
Última atualização enviada que atendeu aos critérios de controle de qualidade
Última verificação
Mais Informações
Termos relacionados a este estudo
Palavras-chave
Termos MeSH relevantes adicionais
Outros números de identificação do estudo
- 2010-0267
Informações sobre medicamentos e dispositivos, documentos de estudo
Estuda um medicamento regulamentado pela FDA dos EUA
Estuda um produto de dispositivo regulamentado pela FDA dos EUA
Essas informações foram obtidas diretamente do site clinicaltrials.gov sem nenhuma alteração. Se você tiver alguma solicitação para alterar, remover ou atualizar os detalhes do seu estudo, entre em contato com register@clinicaltrials.gov. Assim que uma alteração for implementada em clinicaltrials.gov, ela também será atualizada automaticamente em nosso site .
Ensaios clínicos em Tumores Estromais Gastrointestinais
-
Hospital Universitario Virgen de la ArrixacaAinda não está recrutandoDoenças do Fígado | Transplante de Fígado | Neoplasias Hepáticas | Tumores Estromais Gastrointestinais | Metástase | Metástases Hepáticas | Transplante de fígado; Complicações | Câncer de fígado | Distúrbio de Transplante de Fígado | Carcinoma de Fígado | GIST, Maligno | ESSÊNCIA | Metástases | Câncer de Fígado Metastático e outras condiçõesEspanha
-
National Cancer Institute (NCI)ConcluídoTumor Carcinóide Gastrointestinal Metastático | Tumor Carcinóide Gastrointestinal Recorrente | Tumor Carcinóide Gastrointestinal RegionalEstados Unidos
-
Seoul National University HospitalRecrutamentoTumor Submucoso do Trato GastrointestinalRepublica da Coréia
-
National Cancer Institute (NCI)Ativo, não recrutandoTumor Estromal Gastrointestinal Metastático | Sarcoma metastático | Sarcoma localmente avançado | Tumor Estromal Gastrointestinal Localmente Avançado | Tumor Estromal Gastrointestinal Estágio III Gástrico e Omental AJCC v8 | Estágio III Tumor Estromal Gastrointestinal, Esofágico, Colorretal,... e outras condiçõesEstados Unidos
-
National Cheng-Kung University HospitalNational Cheng Kung University; National Research Program for Biopharmaceuticals... e outros colaboradoresConcluídoTumor Submucoso do Trato GastrointestinalTaiwan
-
Centre Leon BerardRecrutamentoTumor Estromal Gastrointestinal Metastático | Tumor Estromal Gastrointestinal Irressecável (GIST) | Tumor Estromal Gastrointestinal Localmente Avançado (GIST)França
-
National Cancer Institute (NCI)RescindidoGastrinoma | Glucagonoma | Insulinoma | Tumor Carcinóide Gastrointestinal Metastático | Tumor Polipeptídico Pancreático | Tumor Carcinóide Gastrointestinal Recorrente | Carcinoma Recorrente de Ilhotas | Somatostatinoma | Tumor Carcinóide Gastrointestinal Regional | Tumor Carcinóide PulmonarEstados Unidos
-
Orlando Health, Inc.RecrutamentoCâncer de pâncreas | Cancro do ducto biliar | Doenças das vias biliares | Câncer Gastrointestinal | Doença dos linfonodos | Cisto Pancreático | Doença pancreática | Tumor Gastrointestinal | Tumor Submucoso do Trato GastrointestinalEstados Unidos
-
National Cancer Institute (NCI)ConcluídoTumor Carcinóide Gastrointestinal Metastático | Tumor Carcinóide Gastrointestinal Recorrente | Carcinoma Recorrente de Ilhotas | Tumor Carcinóide PulmonarCanadá
-
David BushnellNational Cancer Institute (NCI); National Institutes of Health (NIH); Holden Comprehensive...Ativo, não recrutandoTumor Neuroendócrino Gastrointestinal Secretor de Hormônios | Tumor Neuroendócrino MalignoEstados Unidos