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Cadence Modulation to Improve Well-Being, Kinematics and Aerobic Performance in Cyclists

23 december 2019 uppdaterad av: University of Wisconsin, Madison
This study will utilize a combination of cardiovascular analysis, 3D motion capture, and a software package, Metrifit, to monitor measures of well-being to comprehensively evaluate both the musculoskeletal and physiological responses following a HIIT training intervention at EOC as a means of improving performance and potentially reducing injury risk factors. This holistic approach of physiological and biomechanical factors is unprecedented. This is the first interventional study to determine the effect of high intensity training at EOC on cardiovascular performance, kinematics and well-being which may minimize risk of injury factors.

Studieöversikt

Status

Avslutad

Betingelser

Intervention / Behandling

Detaljerad beskrivning

In the first session, each individual will be asked to fill out a questionnaire to regarding cycling experience, prior bike fits (with data sheets when available), and injury history. Maximal aerobic capacity (VO2max) will be determined. During the test, subjects will be asked rate exertion. Before testing, the system will be calibrated with known oxygen and carbon dioxide concentrations. During the test, subjects will be asked to breathe normally through a low dead space bidirectional turbine. Inspired and expired gases will be analyzed for concentrations of O2 and CO2, to determine alveolar gas exchange. Total ventilation (VE), respiratory rate, oxygen consumption (VO2), carbon dioxide (VCO2) will be measured, and respiratory exchange ratio (RER; VCO2/VO2) will be calculated continuously during the test and expressed as a 30-second rolling average.

Participants will return 48 hours later, at which time EOC will be determined after a moderate intensity prolonged cycling exercise (PCE) at seven different cadences. Cadences from 50rpm to 110rpm will be randomly generated and introduced every 3 minutes, followed by a 3 minute cool down at FCC at 40% PP (Figure Subjects will then be pair matched by gender and randomized into control (FCC) or EOC modulation groups.

48 hours following EOC testing, subject will return for a second progressive maximal cycling test performed at FCC or EOC based on group assignment.

Subjects will then participate in a 6 week high intensity training (HIIT) indoor cycling program at their prescribed cadence (FCC or EOC), using cadence meters. Training will consist of three non-consecutive days each week for 60 min, and alternate between two HIIT workouts. Resistance will be increased to meet the HIIT requirement, while cadence will remain at FCC or EOC. Subjects will be asked to warm-up at a light (3/10) workload for 10 minutes, followed by HIIT consisting of 4 minutes at an intensity of 8/10 on the modified Borg, and 90 seconds recovery (2/10). This will be repeated 8 times, followed by 10 minutes of cool down. The alternating HIIT workout will include a 10 minute warm up, followed by 12 intervals lasting 2 minutes at an RPE of 9/10 and 3 minutes of recovery. The session will conclude with a 10 minute cool down.

Within one week of completing their training program, subjects will return for their fourth and final study visit, at which time a VO2max test and kinematic data collection will be repeated at FCC or EOC.

Studietyp

Interventionell

Inskrivning (Faktisk)

25

Fas

  • Inte tillämpbar

Kontakter och platser

Det här avsnittet innehåller kontaktuppgifter för dem som genomför studien och information om var denna studie genomförs.

Studieorter

    • Wisconsin
      • Madison, Wisconsin, Förenta staterna, 53705
        • University Of Wisconsin

Deltagandekriterier

Forskare letar efter personer som passar en viss beskrivning, så kallade behörighetskriterier. Några exempel på dessa kriterier är en persons allmänna hälsotillstånd eller tidigare behandlingar.

Urvalskriterier

Åldrar som är berättigade till studier

18 år till 89 år (Vuxen, Äldre vuxen)

Tar emot friska volontärer

Nej

Kön som är behöriga för studier

Allt

Beskrivning

Inclusion Criteria:

  1. An experienced cyclist will be defined as one with at least 5 years of cycling experience and 5000 miles of training on a road bike with a clipless pedal system.
  2. Able to tolerate strenuous, maximal exercise and comply with a 6 week training protocol
  3. Have access to an indoor trainer or spin bike with a cadence sensor in order to train 3 times per week for 60 minutes

Exclusion Criteria:

  1. Taking medication which could impact cardiovascular function or performance (stimulants, beta-blockers, e.g.)
  2. Significant cardiac or pulmonary disease (congenital cardiac disease, uncontrolled hypertension, uncontrolled asthma, e.g.)
  3. Musculoskeletal injuries that preclude a maximal cycling effort and participation in training program

Studieplan

Det här avsnittet ger detaljer om studieplanen, inklusive hur studien är utformad och vad studien mäter.

Hur är studien utformad?

Designdetaljer

  • Primärt syfte: Övrig
  • Tilldelning: N/A
  • Interventionsmodell: Enskild gruppuppgift
  • Maskning: Ingen (Open Label)

Vapen och interventioner

Deltagargrupp / Arm
Intervention / Behandling
Övrig: Cycling Cadence Modulation
3 initial visits to collect baseline information; 6-week HIIT indoor cycling program at the individual prescribed cadence; final study visit for post-intervention measures.
6-week high intensity training (HIIT) indoor cycling program, described later, at their prescribed cadence (FCC or EOC), using cadence meters.

Vad mäter studien?

Primära resultatmått

Resultatmått
Åtgärdsbeskrivning
Tidsram
Time to exhaustion T(max)
Tidsram: Baseline
time to reach exhaustion
Baseline
Ventilatory threshold (VT)
Tidsram: Baseline
Baseline
Maximal cardiac output
Tidsram: Baseline
Baseline
Maximal stroke volume
Tidsram: Baseline
Baseline
decreased trunk lean
Tidsram: Baseline
decrease in degree of lean in truck
Baseline
decreased ankle dorsiflexion
Tidsram: Baseline
decrease in amount of ankle dorsiflexion
Baseline
decreased knee splay
Tidsram: Baseline
decreased degree of knee splay
Baseline

Sekundära resultatmått

Resultatmått
Åtgärdsbeskrivning
Tidsram
Improved VO2 max
Tidsram: 6 weeks
Increased maximum O2 volume
6 weeks
Increased O2 consumption at VT
Tidsram: 6 weeks
Improved oxygen consumption at ventilatory threshold
6 weeks
Time to VT
Tidsram: 6 weeks
Improved time to reach ventilatory threshold
6 weeks
Time to T(max)
Tidsram: 6 weeks
Improved time to reach exhaustion
6 weeks
decreased trunk lean
Tidsram: 6 weeks
decrease in degree of lean in truck
6 weeks
decreased ankle dorsiflexion
Tidsram: 6 weeks
decrease in amount of ankle dorsiflexion
6 weeks
decreased knee splay
Tidsram: 6 weeks
decreased degree of knee splay
6 weeks
change in overall soreness and fatigue
Tidsram: 6 weeks
decrease in reported soreness and fatigue as measured and reported via Metrifit software
6 weeks

Samarbetspartners och utredare

Det är här du hittar personer och organisationer som är involverade i denna studie.

Utredare

  • Huvudutredare: Andrew M Watson, MD, University of Wisconsin, Madison

Studieavstämningsdatum

Dessa datum spårar framstegen för inlämningar av studieposter och sammanfattande resultat till ClinicalTrials.gov. Studieposter och rapporterade resultat granskas av National Library of Medicine (NLM) för att säkerställa att de uppfyller specifika kvalitetskontrollstandarder innan de publiceras på den offentliga webbplatsen.

Studera stora datum

Studiestart (Faktisk)

26 juni 2017

Primärt slutförande (Faktisk)

2 april 2019

Avslutad studie (Faktisk)

2 april 2019

Studieregistreringsdatum

Först inskickad

22 november 2017

Först inskickad som uppfyllde QC-kriterierna

22 mars 2018

Första postat (Faktisk)

29 mars 2018

Uppdateringar av studier

Senaste uppdatering publicerad (Faktisk)

26 december 2019

Senaste inskickade uppdateringen som uppfyllde QC-kriterierna

23 december 2019

Senast verifierad

1 april 2019

Mer information

Termer relaterade till denna studie

Andra studie-ID-nummer

  • 2017-0131
  • A536110 (Annan identifierare: UW Madison)
  • SMPH\ORTHOPEDIC&REHAB\ORTHO (Annan identifierare: UW Madison)

Läkemedels- och apparatinformation, studiedokument

Studerar en amerikansk FDA-reglerad läkemedelsprodukt

Nej

Studerar en amerikansk FDA-reglerad produktprodukt

Nej

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