NT-proBNP in Acute Dyspnea: Effects on Treatment, Hospitalisation and Costs
NT-proBNP Testing in Patients Presenting to the Emergency Department With Acute Dyspnea: Evaluation of Effects on Treatment, Hospitalisation Rate and Costs
Diagnostic uncertainty in patients with complaints of shortness of breath presenting to the Emergency Department of a hospital may delay treatment and proper care. In patients with shortness of breath due to heart failure increased plasma levels of NT-pro-B-type natriuretic peptide (NT-proBNP) can be demonstrated. The use of NT-proBNP as a biomarker for heart failure in patients presenting to the emergency department with dyspnea might improve care and reduce length of hospital stay.
To investigate the effect of NT-proBNP testing on patient care and time to discharge the NT-proBNP test will be randomized. In patients in the study group, the NT-proBNP plasma level is determined at admission and the physician in charge will immediately receive the result of the test. In patients in the control group blood will be sampled but the physician will recieve no information on the NT-proBNP plasma level.
In our study we will investigate the effect of introduction of NT-proBNP as biomarker for heart failure on treatment, time to discharge and costs.
研究概览
研究类型
注册
阶段
- 不适用
联系人和位置
学习地点
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Rotterdam、荷兰、3015 CE
- Erasmus MC
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
描述
Inclusion Criteria:
- Age 18 years or older
- Acute dyspnea as their most prominent complaint
Exclusion Criteria:
- Acute dyspnea due to a trauma
- Acute dyspnea due to cardiogenic shock
- Renal failure requiring dialysis
学习计划
研究是如何设计的?
设计细节
- 主要用途:诊断
- 分配:随机化
- 介入模型:单组作业
- 屏蔽:单身的
研究衡量的是什么?
主要结果指标
结果测量 |
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出院时间
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Cost of treatment
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次要结果测量
结果测量 |
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Duration of stay at the ED
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Proportion of patients admitted to the hospital
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Proportion of patients admitted to an intensive or coronary care unit
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Specialist consultations
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Medical treatment
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Diagnostic investigations
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合作者和调查者
调查人员
- 首席研究员:Anton H. van den Meiracker, MD, PhD、Erasmus Medical Center
研究记录日期
研究主要日期
学习开始
研究完成
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (估计)
上次提交的符合 QC 标准的更新
最后验证
更多信息
此信息直接从 clinicaltrials.gov 网站检索,没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求,请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改,我们的网站上也会自动更新.
NT-proBNP testing的临床试验
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General Hospital Murska SobotaRoche Pharma AG; Slovenian Research Agency; Murska Sobota Municipiality; Community Health Center...未知
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Washington University School of MedicineUniversity of Abuja Teaching Hospital完全的
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Hospital Universitario Virgen de la ArrixacaJuan Cinca Cuscullola; Pablo García Pavía; Manuel Martinez Selles; Antoni Bayés Genís; Alfonso Varela... 和其他合作者完全的
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NHS Greater Glasgow and ClydeAstraZeneca招聘中