French hospital is studying predictive value of diaphragmatic excursion by echographic assessment at the bedside on need for endotracheal ontubation in COPD patients

Photo by Ibrahim Boran

European Georges Pompidou Hospital is recruiting patients for the clinical trial of Predictability of Echographic Excursion of the Diaphragm for Intubation in COPD- Patients With Acute Respiratory Failure in ED (PREEDICT-ED).

The investigators seek to evaluate if the ultra-sound measure of the diaphragm expansion is predictive of admission into an ICU and/or intubation for patients with COPD.

Every patient coming to the ER with shortness of breath and a known or suspected COPD, will undergo standard of care associated with a diaphragm ultrasound.

The investigators will then gather, through the internal databases of the recruiting hospitals, information about admission into ICU and/or intubation.

The investigators think that this technique will help improve early detection of COPD patient requiring mechanical ventilation, using ultrasound, a non invasive technique.
Inclusion of every lawful age patient presenting to the ER with inclusion criterias

The patient must not have exclusion criteria and must have received the information and consent sheets to be signed jointly.

The indicative completion of the clinical trial will be expected in July 23, 2022.

Evaluate the predictive value of the presence of diaphragmatic dysfunction diagnosed by ultrasound measurement of the diaphragmatic excursion (ED) on the use of invasive mechanical ventilation (IV) and predictive value of the presence of a diaphragmatic dysfunction on the use of invasive mechanical ventilation (IV) is the primary outcome measure.

The study will take place at the Nîmes University Hospital, Nîmes, France; Georges Pompidou European Hospital, Paris, France and Bellepierre Hospital, Saint-Denis, France.

The page dedicated to this clinical trial can be found here: https://ichgcp.net/clinical-trials-registry/NCT04591509.