Examination of the Effects of Four Different Spices on Energy Metabolism

February 7, 2008 updated by: University of Copenhagen

Bioactive Food Ingredients and Energy Metabolism: The Effects of Ginger, Black Pepper, Horseradish and Mustard on Meal-Induced Thermogenesis and Fat Oxidation

The objective of this study is to examine whether four different spices (ginger, black pepper, horseradish and mustard) are able to increase energy metabolism.

Since chili and other spices have been shown to increase energy expenditure compared to placebo, we expect that some or all of the four spices may actually increase energy expenditure - although not to a large degree.

Study Overview

Detailed Description

Several pungent food ingredients, such as chili,and also other bioactive food ingredients, e.g. green tea, have been shown to be able to increase energy expenditure and fat oxidation during the hours following a meal containing the bioactive ingredient. Furthermore, we will also look at the subjects own feelings of appetite and thereby examine whether the appetite is affected by the spicy food. We expect to see some small effects on these parameters.

Study Type

Interventional

Enrollment (Actual)

22

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

      • Frederiksberg, Denmark, DK-1958
        • Department of Human Nutrition, The Royal Veterinary and Agricultural University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 50 years (Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

Male

Description

Inclusion Criteria:

  • male
  • healthy and not use medication (regularly)
  • normal weight
  • non smoker
  • tolerate and like spicy food
  • stable body weight last two months

Exclusion Criteria:

  • increased blood pressure
  • abnormal EKG
  • mental, metabolic and chronic diseases

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Prevention
  • Allocation: Randomized
  • Interventional Model: Crossover Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Placebo Comparator: E
Placebo
Added to a bruch meal
Experimental: A
Spice
added to a brunch meal
Experimental: B
Spice
Added to a brunch meal
Experimental: C
Spice
Added to a brunch meal
Experimental: D
Spice
Added to a brunch meal

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
energy expenditure
Time Frame: November 2007
November 2007

Secondary Outcome Measures

Outcome Measure
Time Frame
blood pressure
Time Frame: December 2007
December 2007
heart rate
Time Frame: December 2007
December 2007
VAS-scores for appetite, hunger, fullness, etc. - and palatability
Time Frame: November 2007
November 2007
tolerance
Time Frame: November 2007
November 2007
Fat and carbohydrate oxidation
Time Frame: November 2007
November 2007
Meal-induced thermogenesis
Time Frame: November 2007
November 2007

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Collaborators

Investigators

  • Study Chair: Arne Astrup, Professor MD, Department of Human Nutrition, RVAU

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

October 1, 2006

Study Completion (Actual)

June 1, 2007

Study Registration Dates

First Submitted

January 28, 2008

First Submitted That Met QC Criteria

February 7, 2008

First Posted (Estimate)

February 8, 2008

Study Record Updates

Last Update Posted (Estimate)

February 8, 2008

Last Update Submitted That Met QC Criteria

February 7, 2008

Last Verified

August 1, 2007

More Information

Terms related to this study

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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