- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00611156
Examination of the Effects of Four Different Spices on Energy Metabolism
February 7, 2008 updated by: University of Copenhagen
Bioactive Food Ingredients and Energy Metabolism: The Effects of Ginger, Black Pepper, Horseradish and Mustard on Meal-Induced Thermogenesis and Fat Oxidation
The objective of this study is to examine whether four different spices (ginger, black pepper, horseradish and mustard) are able to increase energy metabolism.
Since chili and other spices have been shown to increase energy expenditure compared to placebo, we expect that some or all of the four spices may actually increase energy expenditure - although not to a large degree.
Study Overview
Status
Completed
Conditions
Detailed Description
Several pungent food ingredients, such as chili,and also other bioactive food ingredients, e.g.
green tea, have been shown to be able to increase energy expenditure and fat oxidation during the hours following a meal containing the bioactive ingredient.
Furthermore, we will also look at the subjects own feelings of appetite and thereby examine whether the appetite is affected by the spicy food.
We expect to see some small effects on these parameters.
Study Type
Interventional
Enrollment (Actual)
22
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
-
Frederiksberg, Denmark, DK-1958
- Department of Human Nutrition, The Royal Veterinary and Agricultural University
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years to 50 years (Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
Male
Description
Inclusion Criteria:
- male
- healthy and not use medication (regularly)
- normal weight
- non smoker
- tolerate and like spicy food
- stable body weight last two months
Exclusion Criteria:
- increased blood pressure
- abnormal EKG
- mental, metabolic and chronic diseases
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Prevention
- Allocation: Randomized
- Interventional Model: Crossover Assignment
- Masking: Single
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Placebo Comparator: E
Placebo
|
Added to a bruch meal
|
Experimental: A
Spice
|
added to a brunch meal
|
Experimental: B
Spice
|
Added to a brunch meal
|
Experimental: C
Spice
|
Added to a brunch meal
|
Experimental: D
Spice
|
Added to a brunch meal
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
energy expenditure
Time Frame: November 2007
|
November 2007
|
Secondary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
blood pressure
Time Frame: December 2007
|
December 2007
|
heart rate
Time Frame: December 2007
|
December 2007
|
VAS-scores for appetite, hunger, fullness, etc. - and palatability
Time Frame: November 2007
|
November 2007
|
tolerance
Time Frame: November 2007
|
November 2007
|
Fat and carbohydrate oxidation
Time Frame: November 2007
|
November 2007
|
Meal-induced thermogenesis
Time Frame: November 2007
|
November 2007
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Collaborators
Investigators
- Study Chair: Arne Astrup, Professor MD, Department of Human Nutrition, RVAU
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
October 1, 2006
Study Completion (Actual)
June 1, 2007
Study Registration Dates
First Submitted
January 28, 2008
First Submitted That Met QC Criteria
February 7, 2008
First Posted (Estimate)
February 8, 2008
Study Record Updates
Last Update Posted (Estimate)
February 8, 2008
Last Update Submitted That Met QC Criteria
February 7, 2008
Last Verified
August 1, 2007
More Information
Terms related to this study
Keywords
Other Study ID Numbers
- B228-IHE-2006-NTG
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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