Potential Nosocomial Infection Prevention Via Modification of Anesthesia Intraoperative Aseptic Practice

Before and After Study Evaluating Deployment of the Sprixx GJ Personal Hand Hygiene Device in the Intra-Operative Environment

We hypothesized that by improving hand hygiene compliance in the operative environment, we would reduce horizontal transmission of pathogenic bacteria to surgical patients.

Study Overview

• Status: Completed
• Conditions: Nosocomial Infections

Detailed Description

We performed an observational study evaluating provider adherence to these techniques. We then sought to increase hand hygiene compliance through the use of a point of care alcohol based hand hygiene device. We hypothesized that increased hand hygiene compliance would reduce bacterial contamination of the anesthesia workspace and peripheral intravenous tubing, and ultimately reducing overall morbidity and mortality secondary to a reduction in nosocomial infection rates.

• Study Type: Observational
• Enrollment (Actual): 114

Contacts and Locations

Study Locations

• United States
  • New Hampshire
    • Lebanon, New Hampshire, United States, 03756
      • Dartmouth-Hitchcock Medical Center

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child; Adult; Older Adult
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Probability Sample

Study Population

Operating Rooms were randomized and patients in these rooms were enrolled for the study.

Description

Inclusion Criteria:

• Patients present in operating rooms randomized to study.

Exclusion Criteria:

• Patients that were already enrolled in study and return to the operating room.

Study Plan

How is the study designed?

Design Details

• Observational Models: Ecologic or Community
• Time Perspectives: Prospective

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort
Before (Control); Study group representative of standard practice
After(Treatment); After treatment group with the personal hand hygiene device ie. Device Group.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
The presence of a positive culture on the previously sterile patient stopcock set, and the presence of multidrug resistant bacteria	Beginning and end of surgical case

Secondary Outcome Measures

Outcome Measure	Time Frame
Reduction of bacterial contamination on predetermined sites on the anesthesia machine	Beginning and End of Surgical Case
Decreased length of stay	Postoperatively
Nosocomial infection rates	within 30 days postoperatively
Mortality	Within 30 days postoperatively

Collaborators and Investigators

• Sponsor: Dartmouth-Hitchcock Medical Center
• Collaborators: Harbor Medical Inc.
• Investigators: Principal Investigator: Matthew D Koff, M.D. M.S., Dartmouth-Hitchocck Medical Center

Publications and helpful links

General Publications

• Koff MD, Loftus RW, Burchman CC, Schwartzman JD, Read ME, Henry ES, Beach ML. Reduction in intraoperative bacterial contamination of peripheral intravenous tubing through the use of a novel device. Anesthesiology. 2009 May;110(5):978-85. doi: 10.1097/ALN.0b013e3181a06ec3.

Study record dates

Study Major Dates

• Study Start: July 1, 2007
• Primary Completion (Actual): August 1, 2007
• Study Completion (Actual): October 1, 2007

Study Registration Dates

• First Submitted: February 5, 2008
• First Submitted That Met QC Criteria: February 14, 2008
• First Posted (Estimate): February 15, 2008

Study Record Updates

• Last Update Posted (Estimate): February 15, 2008
• Last Update Submitted That Met QC Criteria: February 14, 2008
• Last Verified: February 1, 2008

More Information

Terms related to this study

• Keywords: Hand Hygiene; Anesthesia Workspace; Hospital Acquired Infections; Alcohol Based Cleanser; Bacterial Contamination
• Additional Relevant MeSH Terms: Pathologic Processes; Disease Attributes; Iatrogenic Disease; Infections; Cross Infection
• Other Study ID Numbers: CPHS# 20655