Physical Activity Intervention for Lung Cancer Survivors

The purpose of this study is to learn how many lung cancer survivors will agree to a physical activity program. We also want to know if lung cancer survivors benefit from this program. This information will help us to develop our services for lung cancer survivors.

Study Overview

• Status: Completed
• Conditions: Lung Cancer; Survivor
• Intervention / Treatment: Behavioral: interview and physical activity; Behavioral: interview and wait list

• Study Type: Observational
• Enrollment (Actual): 52

Contacts and Locations

Study Locations

• United States
  • New York
    • New York, New York, United States, 10065
      • Memorial Sloan Kettering Cancer Center

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 21 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No

• Sampling Method: Probability Sample

Study Population

In total, we will recruit and enroll a random sample of 70 lung cancer survivors who are at least one year post thoracic surgical resection and have no evidence of NSCLC or any other cancer at the time of study enrollment and not receiving any adjuvant treatment.

Description

Inclusion Criteria:

• Diagnosis and treatment at MSKCC of primary NSCLC; and/or pulmonary carcinoid;
• At least one year post thoracic surgical resection;
• Have no evidence of NSCLC or any other cancer at the time of study enrollment and not receiving any cancer treatment;
• Currently sedentary or insufficiently active, defined by the American College of Sports Medicine (ACSM) and the Centers for Disease Control and Prevention as less than a total of 150 minutes of at least moderate intensity PA per week;
• Able to complete a six-minute walk test (6MWT);
• Able to provide informed consent.

FOCUS GROUP ONLY:

• Completed the Physical Activity program offered through this study (08067);

Exclusion Criteria:

• Presence of one of the following medical factors at screening:

  • regular use of an ambulatory aid (cane or walker);
  • resting oxygen saturation less than 88%;
  • inability to walk due to severe arthritis or other musculoskeletal problems;
  • a diagnosis of unstable angina in the previous 6 weeks;
  • a heart attack, angioplasty or heart surgery in the previous 3 months;
  • current heart rate <50 or >120 at rest; current uncontrolled hypertension;
  • current significant valvular heart disease or decompensated congestive heart failure and
  • patient reported pain of any origin that would preclude participation in the proposed PA intervention
• Evidence of significant medical cognitive or psychiatric disturbance sufficient, in the investigator's judgment, to preclude participation in the intervention
• Self-reporting of greater than 60 minutes of vigorous activity per week or 150 minutes of moderate intensity PA per week.
• Patient resides at more than two hours travel distance from the Center
• Insufficient English fluency to complete evaluation tools.

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
1; Arm 1 - Physical Activity intervention	Behavioral: interview and physical activity; For Arm 1 participants in the Physical Activity intervention condition will be assessed at baseline, and postintervention Follow-up (at 12 weeks post baseline).
2; Arm 2 - Wait-list control	Behavioral: interview and wait list; Participants in the control condition (Arm 2)will be assessed at baseline and 12 weeks post baseline (Follow-up). At this time, the PA intervention will be offered at no cost to the participants in the control condition. If the waitlist participant chooses to complete the PA intervention after the 12 week waitlist period, program satisfaction will be assessed after study completion.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
To evaluate the feasibility (acceptability, adherence, treatment integrity, retention, participant satisfaction) of implementing a physical activity intervention trial among sedentary and insufficiently active lung cancer survivors.	conclusion of the study

Secondary Outcome Measures

Outcome Measure	Time Frame
Obtain preliminary data on effect of a physical activity intervention on functional ability, health-related QOL, dyspnea, fatigue, balance, strength & self-report physical activity among sedentary and insufficiently active lung cancer survivors	conclusion of the study
To obtain preliminary data on factors associated with feasibility using variables from Social Cognitive Theory and assess their relationship with treatment adherence and dropout.	conclusion of the study

Collaborators and Investigators

• Sponsor: Memorial Sloan Kettering Cancer Center
• Collaborators: Fox Chase Cancer Center; Brown University; University of Alberta, Physical Education
• Investigators: Principal Investigator: Jamie Ostroff, PhD, Memorial Sloan Kettering Cancer Center

Publications and helpful links

Helpful Links

• Memorial Sloan Kettering Cancer Center

Study record dates

Study Major Dates

• Study Start (Actual): June 10, 2008
• Primary Completion (Actual): June 5, 2023
• Study Completion (Actual): June 5, 2023

Study Registration Dates

• First Submitted: July 16, 2008
• First Submitted That Met QC Criteria: July 17, 2008
• First Posted (Estimated): July 18, 2008

Study Record Updates

• Last Update Posted (Actual): June 7, 2023
• Last Update Submitted That Met QC Criteria: June 6, 2023
• Last Verified: June 1, 2023

More Information

Terms related to this study

• Keywords: Physical Activity; Survivor; NED; 08-067
• Additional Relevant MeSH Terms: Respiratory Tract Diseases; Neoplasms; Lung Diseases; Neoplasms by Site; Respiratory Tract Neoplasms; Thoracic Neoplasms; Lung Neoplasms
• Other Study ID Numbers: 08-067