GlideScope Versus Direct Laryngoscope for Emergency Intubation

May 4, 2023 updated by: University of Maryland, Baltimore

GlideScope vs. Direct Laryngoscope for Emergency Intubation

The purpose of this study is to assess if the GlideScope video laryngoscope is superior to the Macintosh direct laryngoscope for definitive airway management in acutely-injured patients.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

On admission to the emergency department following traumatic injury, many patients require placement of an artificial airway to support their breathing, provide oxygen and protect their airway. This procedure is accomplished through a number of different techniques and few studies have compared these techniques in order to establish the best method. We will compare an older technique using a metal handle and blade that allows for direct visualization of the vocal cords (direct laryngoscopy) to a newer technique that employs a fiberoptic bundle imbedded in a handle that allows indirect visualization of the vocal cords during placement of the artificial airway. The newer technique has the theoretical advantage of being more useful in patients with abnormal airways which are frequently encountered in trauma patients. Since both techniques are currently employed routinely in our institution, we will randomize all trauma admission to have an initial attempt with one of the two techniques in order to perform a randomized, unblinded trial.

Study Type

Interventional

Enrollment (Actual)

623

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • United States
    • Maryland
      • Baltimore, Maryland, United States, 21201
        • R Adams Cowley Shock Trauma Center

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • require emergency intubation

Exclusion Criteria:

  • age < 18
  • require surgical airway on initial assessment
  • have known or strongly suspected spinal cord injury

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: direct laryngoscope
emergency intubation with direct laryngoscopy technique
Device: type of laryngoscope
Patients who require emergency rapid sequence intubation are randomized to intubation with either the direct laryngoscope or the video laryngoscope
Other Names:
  • Macintosh direct laryngoscope vs. GlideScope video laryngoscope
Active Comparator: video laryngoscope
emergency intubation with video laryngoscopy technique
Device: type of laryngoscope
Patients who require emergency rapid sequence intubation are randomized to intubation with either the direct laryngoscope or the video laryngoscope
Other Names:
  • Macintosh direct laryngoscope vs. GlideScope video laryngoscope

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Number of Participants Who Survived to Hospital Discharge
Time Frame: 2 weeks, on average
Assessment of whether or not the patient was discharged alive from the study center
2 weeks, on average

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Length of Time to Perform the Intubation Procedure
Time Frame: Up to 100 seconds
How long (seconds) it takes the provider to perform the intubation procedure.
Up to 100 seconds

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

University of Maryland, Baltimore

Investigators

  • Principal Investigator: Dale Yeatts, MD, University of Maryland

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

July 1, 2008

Primary Completion (Actual)

November 16, 2016

Study Completion (Actual)

November 16, 2016

Study Registration Dates

First Submitted

October 22, 2010

First Submitted That Met QC Criteria

November 3, 2010

First Posted (Estimated)

November 5, 2010

Study Record Updates

Last Update Posted (Actual)

June 1, 2023

Last Update Submitted That Met QC Criteria

May 4, 2023

Last Verified

June 1, 2018

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • HP-00042451

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

IPD Plan Description

None exists

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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