Comparison of Intubation Duration Between Rapid Sequence Intubation (RSI) Technique and Non-RSI Technique

Comparison of Intubation Duration Between Rapid Sequence Intubation Technique and Non- Rapid Sequence Intubation Technique in Siriraj Hospital by Emergency Medicine Residences

The purpose of this study is to evaluate intubation duration between rapid sequence intubation technique (RSI) and non-rapid sequence intubation technique (non-RSI) performed by emergency medicine residents in Siriraj hospital.

Study Overview

• Status: Completed
• Conditions: Tracheal Intubation Morbidity
• Intervention / Treatment: Drug: RSI

Detailed Description

A prospective cohort study was conducted in the non-traumatic emergency department (ED).

• Study Type: Interventional
• Enrollment (Actual): 224
• Phase: Phase 4

Contacts and Locations

Study Locations

• Thailand
  • Bangkok, Thailand, 10700
    • Siriraj Hospital

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• patients required airway control by tracheal intubation

Exclusion Criteria:

• cardiac arrest

Study Plan

How is the study designed?

Design Details

• Allocation: Non-Randomized
• Interventional Model: Parallel Assignment
• Masking: None (Open Label)

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: RSI technique; Intubation with RSI technique. RSI technique includes the administration of inductive and neuromuscular blocking agents to facilitate an intubation. In this study, we have no restriction of medication use. Physicians can chose any of medication as an individual judgement.	Drug: RSI; All medications are administered only one dose before intubation Anesthetics: Propofol 2-2.5 mg/kg Thiopental 3-5mg/kg Etomidate 1-2mg/kg Neuromuscular blocking agents: Succinylcholine 1-1.5mg/kg Rocuronium 0.9mg/kg Opioid: Fentanyl 1-2ug/kg; Other Names: Rapid Sequence Intubation
No Intervention: Non-RSI; Intubation without RSI technique. No any medication use during intubation period.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
The overall intubation duration	The overall intubation duration is recorded on the decision to intubation patient and corresponds to the time of confirmation the endotracheal position by chest auscultation	Participants will be followed for the overall intubation duration until confirmation the endotracheal position, an expected average of 2 minutes

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
the intubation duration	The intubation duration (Ti), it is defined from application the laryngoscope into the patient's mouth to the time of confirmation an endotracheal position	Participants will be followed for the intubation duration until confirmation the endotracheal position, an expected average of 5 minutes
Complication	Complications occur during and after intubation peroid are recorded and monitored until patients are discharged fromt the hospital.	Participants will be followed in the period of staying in the emergency room and hospital, an expected average of 4 weeks

Collaborators and Investigators

• Sponsor: Siriraj Hospital
• Investigators: Principal Investigator: Mingkwan Wongyingsinn, M.D., Siriraj Hospital

Study record dates

Study Major Dates

• Study Start: July 1, 2008
• Primary Completion (Actual): December 1, 2012
• Study Completion (Actual): December 1, 2013

Study Registration Dates

• First Submitted: November 9, 2011
• First Submitted That Met QC Criteria: November 17, 2011
• First Posted (Estimate): November 18, 2011

Study Record Updates

• Last Update Posted (Estimate): June 2, 2016
• Last Update Submitted That Met QC Criteria: June 1, 2016
• Last Verified: June 1, 2016

More Information

Terms related to this study

• Other Study ID Numbers: SIRB213