Stress Echocardiography Versus Coronary Angiography for Left Main Stenosis Detection (ESTRIE-TC)

June 24, 2013 updated by: Paul Farand, Université de Sherbrooke

Évaluation de l'Echographie de Stress Par Comparaison à la Coronarographie Comme Outil Non Invasif de détection de la resténose Intra endoprothèse du Tronc Commun

Left main stenosis use to be treated by bypass but with the improvement of angioplasty techniques, an increasing number of patients are submit to left main coronary angioplasty. Consequences of left main intra stent stenosis can be disastrous yet, for the moment, no precise recommendation concerning the follow up of these patients exist. The investigators ought to determine if stress echocardiography can predict left main intra stent stenosis as well (non inferiorly)as control angiography that use to be done.

Study Overview

Status

Withdrawn

Conditions

Intervention / Treatment

Detailed Description

All patients of the study will pass coronary angiogram and stress echocardiography (treadmill of dobutamine).

Study Type

Observational

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Canada
    • Quebec
      • Sherbrooke, Quebec, Canada, J1H 5N4
        • Centre Hospitalier Universitaire de Sherbrooke, departement de cardiologie

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

Patients presenting to teaching hospital or stent from community hospitals to teaching hospital and having left main angioplasty

Description

Inclusion Criteria:

  • patients over 18 years old able to give consent and having had left main angioplasty.

Exclusion Criteria:

  • Bypass on the left anterior descending coronary artery or left circumflex (" protected left main ")
  • Treating physician judge that angiography need to be done straightaway
  • Follow up elsewhere than the CHUS
  • Patient refusal
  • Pregnant women
  • Stress echo contraindication(Severe high blood pressure or malignant arrhythmia)or condition that limits interpretation (Left bundle branch block or pacemaker rhythm)

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Observational Models: Cohort
  • Time Perspectives: Prospective

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Stress echography
Nine to twelve months after their left main angioplasty, patients will go through a stress echo and then the usual control angiography (done routinely in most patient in our center). Patients will act as their own control.
Other: Stress echocardiography
Patients able to exercise will have a treadmill test + echography; the others will have a dobutamine echography.
Other Names:
  • Dobutamine echocardiography
  • Treadmill echocardiography

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Correlation between stress echocardiography results for the detection of left main prosthesis stenosis with coronary angiogram results.
Time Frame: 9 to 12 months after left main angioplasty
9 to 12 months after left main angioplasty

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Université de Sherbrooke

Investigators

  • Principal Investigator: Paul Farand, Cardiologue, Centre de recherche du Centre hospitalier Universitaire de Sherbrooke

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

July 1, 2010

Primary Completion (Anticipated)

July 1, 2012

Study Completion (Anticipated)

July 1, 2013

Study Registration Dates

First Submitted

July 16, 2010

First Submitted That Met QC Criteria

June 14, 2012

First Posted (Estimate)

June 15, 2012

Study Record Updates

Last Update Posted (Estimate)

June 26, 2013

Last Update Submitted That Met QC Criteria

June 24, 2013

Last Verified

June 1, 2013

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • projet #10-011

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on Left Main Coronary Artery Disease

Clinical Trials on Stress echocardiography

Search Similar Trials

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Rwanda

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations

3
Subscribe