Pseudoexfoliation Syndrome in Myopes

Pseudoexfoliation Syndrome in Myopes Defined With Optical Low Coherence Reflectometry

A retrospective study of 5753 eyes of cataract surgery patients was conducted at our Clinic. Ocular optical components measured by optical low coherence reflectometry biometer LENSTAR LS 900® of the cataract myopic eyes with pseudoexfoliation syndrome were put in comparison with those of cataract myopic eyes group without pseudoexfoliation syndrome.

Study Overview

• Status: Completed
• Conditions: Pseudoexfoliation Syndrome in Cataract Myopic Eyes

Detailed Description

A retrospective study of 5753 eyes of cataract surgery patients was conducted at investigators Clinic in a period of 2.5 years. Pseudoexfoliation syndrome was found in 255 eyes. There were only 26 cataract myopic eyes with pseudoexfoliation syndrome. Refractive eye state was defined by preoperatively calculated emmetropization intraocular lens (IOL) value done by optical low coherence reflectometry biometer LENSTAR LS 900®. Ocular optical components of the cataract myopic eyes with pseudoexfoliation syndrome measured by this biometer were put in comparison with matched cataract myopic eyes group without pseudoexfoliation syndrome that have emmetropization IOL value within the same range as the cataract myopic eyes with pseudoexfoliation syndrome.

• Study Type: Observational
• Enrollment (Actual): 5753

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 40 years and older (ADULT, OLDER_ADULT)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Probability Sample

Study Population

5753 eyes of cataract surgery patients ≥ 40 years old

Description

Inclusion Criteria:

• cataract surgery patients ≥ 40 years old

Exclusion Criteria:

• cataract surgery patients < 40 years old

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort
eyes with pseudoexfoliation syndrome; cataract myopic eyes with pseudoexfoliation syndrome
eyes without pseudoexfoliation syndrome; cataract myopic eyes without pseudoexfoliation syndrome

Collaborators and Investigators

• Sponsor: General Hospital Sveti Duh

Study record dates

Study Major Dates

• Study Start: August 1, 2009
• Primary Completion (ACTUAL): January 1, 2012
• Study Completion (ACTUAL): January 1, 2012

Study Registration Dates

• First Submitted: July 7, 2012
• First Submitted That Met QC Criteria: July 10, 2012
• First Posted (ESTIMATE): July 11, 2012

Study Record Updates

• Last Update Posted (ESTIMATE): July 11, 2012
• Last Update Submitted That Met QC Criteria: July 10, 2012
• Last Verified: July 1, 2012

More Information

Terms related to this study

• Keywords: cataract; myopia; pseudoexfoliation syndrome; optical low coherence reflectometry; ocular optical components
• Additional Relevant MeSH Terms: Pathologic Processes; Eye Diseases; Disease; Uveal Diseases; Lens Diseases; Iris Diseases; Syndrome; Cataract; Exfoliation Syndrome
• Other Study ID Numbers: 04072012MB; 04072012UECUHSD (OTHER: University Eye Clinic, University Hospital "Sveti Duh")