Procalcitonin Ratio's Impact on the Decision Upon On-demand Relaparotomy in Septic Peritonitis

Procalcitonin Ratio's Impact on the Decision Upon On-demand Relaparotomy in Septic Peritonitis


Lead Sponsor: CHIR-Net

Source CHIR-Net
Brief Summary

Procalcitonin (PCT) serum levels are monitored in patients with secondary peritonitis after initial operative focus elimination to investigate the PCT ratio's impact on decision-making for or against early relaparotomy in the on-demand relaparotomy concept of secondary septic peritonitis.

Overall Status Completed
Start Date 2009-01-01
Completion Date 2012-12-01
Primary Completion Date 2011-12-01
Study Type Observational
Primary Outcome
Measure Time Frame
prediction of focus elimination: cured patients versus patients with persisting peritonitis (definitions see below) participants will be followed for the duration of hospital stay, an expected average of 21 days
Enrollment 234

Sampling Method:

Non-Probability Sample


Inclusion Criteria: - age >18 years - necessity for operative intervention to eliminate an infectious peritoneal / abdominal focus after organ perforation - abdominal sepsis according to the American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference definition Exclusion Criteria: - pregnancy - immunosuppressive medication



Minimum Age:

18 Years

Maximum Age:


Healthy Volunteers:


Facility: Klinikum rechts der Isar der TU München
Location Countries


Verification Date


Responsible Party

Type: Sponsor

Has Expanded Access No
Condition Browse
Arm Group

Label: eliminated infectious abdominal focus

Label: persisting/progressing infectious abdominal focus

Study Design Info

Observational Model: Cohort

Time Perspective: Prospective

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