Effectiveness of Silver Nitrate Solution in the Treatment of Anal Fistula

Effectiveness of Silver Nitrate Solution in the Treatment of Anal Fistula: A Novel Strategy for Managing Anal Fistula

Effectiveness of silver nitrate solution in treatment of anal fistula is is aimed to be investigated.

Study Overview

• Status: Unknown
• Conditions: Anal Fistula

Detailed Description

The anal fistula is a granulation tissue-lined tract, we thought of a way to ablate this granulation tissue using a chemical agent, which would eventually induce healing with fibrosis and closure of the tract without any surgical intervention. Aiming to reduce the surgery related complications; we investigated the effectiveness of silver nitrate solution as a chemical agent in the treatment of anal fistula.

• Study Type: Observational
• Enrollment (Anticipated): 70

Contacts and Locations

Study Locations

• Turkey
  • Istanbul, Turkey, 34893
    • Recruiting
    • MarmaraUSM
    • Contact: M.Unit Ugurlu, MD; Phone Number: +905324108010; Email: umitugurlu@gmail.com
    • Sub-Investigator: M.Umit Ugurlu, MD

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 80 years (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: Male

• Sampling Method: Non-Probability Sample

Study Population

Patients with the diagnosis of anal fistula

Description

Inclusion Criteria:

All patients with the diagnosis of anal fistula Patients with recurrence

Exclusion Criteria:

Patients who do not sign the informed consent

Study Plan

How is the study designed?

Design Details

• Observational Models: Cohort
• Time Perspectives: Prospective

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort
Silver Nitrate; Irrigation of fistula tract with 1% silver nitrate solution for all patients who accepts the study and signed the written informed consent form.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Number of anal fistula patients treated with silver nitrate solution.	The primary end point in the study was to assess the efficacy of the silver nitrate in the treatment of anal fistula. The number of anal fistula patients who are treated with silver nitrate solution will be calculated. The role of silver nitrate solution in anal fistula treatment will be investigated	1 year

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Therapeutic factors	The secondary end point was to identify the clinical and therapeutic factors that significantly affect the primary endpoint.	1 year

Collaborators and Investigators

• Sponsor: Marmara University
• Investigators: Study Chair: S.CUMHUR YEGEN, MD, Marmara University

Study record dates

Study Major Dates

• Study Start: August 1, 2013
• Primary Completion (Anticipated): January 1, 2014
• Study Completion (Anticipated): March 1, 2014

Study Registration Dates

• First Submitted: August 19, 2013
• First Submitted That Met QC Criteria: August 22, 2013
• First Posted (Estimate): August 28, 2013

Study Record Updates

• Last Update Posted (Estimate): August 28, 2013
• Last Update Submitted That Met QC Criteria: August 22, 2013
• Last Verified: August 1, 2013

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Digestive System Diseases; Gastrointestinal Diseases; Intestinal Diseases; Pathological Conditions, Anatomical; Rectal Diseases; Intestinal Fistula; Digestive System Fistula; Fistula; Rectal Fistula
• Other Study ID Numbers: MarmaraUSM