Feasibility of Strength Training in Patients Hospitalized Due to COPD

Feasibility of Progressive Knee Extension Strength Training Using Ankle Weight Cuffs in Patients Hospitalized With COPD in Acute Exacerbation

To examine the feasibility of progressive unilateral knee-extension strength training using ankle weight cuffs in patients hospitalized due to acute exacerbation in COPD

Study Overview

• Status: Completed
• Conditions: Muscle Weakness; COPD
• Intervention / Treatment: Other: Resistance training in AECOPD

Detailed Description

We decided that feasibility is indicated if: 1) the absolute training loads increase progressively, 2) more than 80% of the planned training sessions are completed, and 3)if the absolute training loads do not exceed 20 kg (2 x10kg weight cuffs) for 90% of patients.

• Study Type: Interventional
• Enrollment (Actual): 40
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Denmark
  • Frederikssund, Denmark, 3600
    • Nordsjællands Hospital - Frederikssund

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child; Adult; Older Adult
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• Have a primary diagnosis of COPD
• Be admitted to the pulmonary ward due to an exacerbation in COPD
• Provide informed consent to participation in the study
• Be able to maintain an upright position on a chair
• Be able to be guided to training and understand instructions for participating

Exclusion Criteria:

Patients suffering from diseases that prevents the use of wrist weights such as

• Deep venous thrombosis (DVT)
• Erysipelas
• Painful edema of the limbs
• Lack of ability to walk, habitually
• Predicted hospital stay of less than four days as predicted by a pulmonary physician
• Patients admitted Friday night or Saturday morning cannot be stared up within 24 hours of admittance

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: N/A
• Interventional Model: Single Group Assignment
• Masking: None (Open Label)

Number of Arms

1

Arms and Interventions

Participant Group / Arm

Intervention / Treatment

Experimental: Resistance training in AECOPD; The patients conduct daily training during admission with weight cuff 3 set of 10 rep.

Other: Resistance training in AECOPD; The patients begin training on day 1 of admittance. The training consists of knee extension performed in the sitting position on the bed with a 90 degrees of flexion of the knees. The weight cuffs are tired to the angles with a weight corresponding to 10 RM (the weight lifted 10 times). The weights and exercises are subjected to supervision on daily basis by the physiotherapist. The weight is increased after every set of training if more than 10 rep. can be performed with a given weight. Limitations to exercise is also recorded along with the degree of dyspnoea as assessed by the Borg CR10, possible oxygen supplementation and saturation is recorded before and following exercise.; Other Names: Strength training; Weight cuffs; hospitalization

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Increase of training load during admission	Change in training loads measured by the number of kilos lifted using ankle weight cuffs in 3 sets of 10 repetition maximum at the first training day to the number of kilos lifted at the last training day	The patients will be followed for the duration of hospital stay, an expected average of 6 days

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Maximal isometric knee extension strength	Maximal isometric knee extension strength is measured unilaterally by a fixated handheld dynamometer. The test will be performed upon admission and at the day of discharge	The patients will be followed for the duration of hospital stay, an expected average of 6 days
Sit-to- stand- test	The number of times the patient comes to full standing position in 30 seconds. The Sit to Stand test provides a measurement of a person's lower body (particularly quadriceps) strength. This is associated with the ability to perform lifestyle tasks such as climbing stairs, getting in and out of a vehicle or bath. The test will be performed upon admission and on the day of discharge	The patients will be followed for the duration of hospital stay, an expected average of 6 days
Timed Up and Go (TUG)	A test used to assess a person's mobility and requires both static and dynamic balance. The time that a person takes to rise from a chair, walk three metres, turn around, walk back to the chair, and sit Down. The test will be performed at admission and at the day of discharge	The patients will be followed for the duration of hospital stay, an expected average of 6 days

Collaborators and Investigators

• Sponsor: Frederikssunds Hospital, Denmark
• Collaborators: Copenhagen University Hospital, Hvidovre
• Investigators: Study Chair: Morten T Kristensen, PhD, Copenhagen University Hospital, Hvidovre; Principal Investigator: Linette M Kofod, PT, Nordsjællands Hospital - Frederikssund

Study record dates

Study Major Dates

• Study Start: October 1, 2013
• Primary Completion (Actual): January 1, 2014
• Study Completion (Actual): January 1, 2014

Study Registration Dates

• First Submitted: October 30, 2013
• First Submitted That Met QC Criteria: November 5, 2013
• First Posted (Estimate): November 11, 2013

Study Record Updates

• Last Update Posted (Estimate): February 11, 2014
• Last Update Submitted That Met QC Criteria: February 9, 2014
• Last Verified: February 1, 2014

More Information

Terms related to this study

• Keywords: Physiotherapy; Muscle strength; Resistance training; COPD acute exacerbation; Handheld dynamometer
• Additional Relevant MeSH Terms: Pathologic Processes; Nervous System Diseases; Neurologic Manifestations; Musculoskeletal Diseases; Muscular Diseases; Neuromuscular Manifestations; Muscle Weakness
• Other Study ID Numbers: 210977