An Assessment of the Prevalence of Spatial Neglect in Stroke Survivors With Aphasia

An Assessment of the Prevalence of Spatial Neglect in Stroke Survivors With Aphasia With Option of Prism Adaptation Treatment (PAT) Protocol

The purpose of this study is to determine if stroke survivors with aphasia have spatial neglect (Phase 1). If they are determined to have the condition Phase 2 will be offered: which is prism adaptation treatment. This is a pilot study that will be performed with 4-5 subjects.

Study Overview

• Status: Completed
• Conditions: Stroke; Aphasia; Spatial Neglect
• Intervention / Treatment: Behavioral: prism adaptation treatment

Detailed Description

Spatial neglect is a disorder that may occur after a brain injury such as stroke. Spatial neglect may affect stroke recovery. One example of this heterogeneous condition: Individuals with spatial neglect often pay more attention to one side of what they are looking at, even though they have no difficulty seeing. The study investigators would like to screen stroke survivors with aphasia because they may also have spatial neglect (right neglect after left hemisphere stroke), which is said by the literature to occur in 25% of cases. If it is identified, a treatment approach will be offered, to attempt to remediate the condition using prism goggles, following a prism treatment protocol based on previous studies.

• Study Type: Observational
• Enrollment (Actual): 60

Contacts and Locations

Study Locations

• United States
  • New Jersey
    • Maywood, New Jersey, United States, 07607
      • Adler Aphasia Center

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Probability Sample

Study Population

Stroke survivors with aphasia and spatial neglect

Description

Inclusion Criteria:

• A stroke survivor with aphasia who is a member at the Adler Aphasia Center

Exclusion Criteria:

• Has a history of brain tumor, head injury with loss of consciousness, dementia, alzheimers

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort

Intervention / Treatment

Observational; prism adaptation treatment

Behavioral: prism adaptation treatment; Prism goggles shift the image one sees toward the left (because the thicker portion of the glass lens is on the right). This will change the perception of where the image is in space, causing the person to adapt. The after-effects of the treatment is what is important. It has been shown to make it easier for people to move in the right space (if have right neglect) or improves ability to complete other functional tasks.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Kessler Foundation Neglect Assessment Process	a performance based and behavioral measure for spatial neglect that utilizes and standardizes the administration of the Catherine Bergego Scale (CBS)	2 weeks

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Behavior Inattention Test	Conventional subtest, a set of paper and pencil test for spatial neglect	2 weeks
Barthel Index	A functional independence assessment of daily tasks	2 weeks
University of Alabama at Birmingham (UAB) Life Space assessment	a self graded assessment on community mobility and participation	2 weeks

Collaborators and Investigators

• Sponsor: Kessler Foundation
• Investigators: Principal Investigator: Kimberly Hreha, OT, Kessler Foundation/Kessler Institute for Rehabilitation; Principal Investigator: A.M. Barrett, M.D., Kessler Foundation

Publications and helpful links

Helpful Links

• Kessler Foundation

Study record dates

Study Major Dates

• Study Start: February 1, 2014
• Primary Completion (Actual): December 1, 2016
• Study Completion (Actual): December 1, 2016

Study Registration Dates

• First Submitted: February 12, 2014
• First Submitted That Met QC Criteria: February 20, 2014
• First Posted (Estimate): February 21, 2014

Study Record Updates

• Last Update Posted (Actual): August 21, 2017
• Last Update Submitted That Met QC Criteria: August 16, 2017
• Last Verified: August 1, 2017

More Information

Terms related to this study

• Keywords: aphasia; spatial neglect
• Additional Relevant MeSH Terms: Cardiovascular Diseases; Vascular Diseases; Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Neurologic Manifestations; Neurobehavioral Manifestations; Language Disorders; Communication Disorders; Speech Disorders; Stroke; Aphasia; Perceptual Disorders
• Other Study ID Numbers: R-802-13