- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT02087319
Effect of PRP on the Therapy for Hair Growth
Application and Evaluation of PRP on the Therapy for Hair Loss Disorder
Study Overview
Status
Conditions
Intervention / Treatment
Detailed Description
Hair loss is a disorder in which the hair undergoes aberration growth cycles and falls out from scalp. A number of factors like hormones, genetic factors, diet, endocrine abnormalities, systemic illnesses, drug intake, and hair shaft abnormalities may cause hair loss. Androgen alopecia or male pattern baldness is the most common cause of hair loss caused by progressive shortening of the anagen and increased number of hair follicles in telogen, which has a significant influence on psychological distress.
Except medical treatment and baldness surgery, a new interest in treating hair loss and baldness has been stimulated by using platelet plasma growth factors obtained from the patient's own platelet-rich plasma (PRP). PRP is a portion of plasma fraction of autologous blood having a high concentration of thrombocytes, and can be activated by Thrombin to release multiple growth factors, including platelet-derived growth factor (PDGF), vascular endothelial growth factor (VEGF), epidermal growth factor (EGF), insulin-like growth factor (IGF), and transforming growth factor beta (TGF-β). PRP is known for the capacity to stimulate cell proliferation and differentiation. The action of platelet plasma growth factors on the development of hair follicles has already been established. PRP has also been shown to increase the yield of implanted follicular units during male baldness surgery.
Our study will focus on the advantage of PRP for the treatment of hair loss and male pattern baldness. PRP from autologous blood can be mixed with thrombin in appropriate ratio and inject into the regions on scalp which is interested. We will track and evaluate regularly the effect and efficiency of PRP on human hair growth.
Study Type
Enrollment (Actual)
Phase
- Not Applicable
Contacts and Locations
Study Locations
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-
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Taichung, Taiwan
- China Medical University Hospital
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Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Description
Inclusion Criteria:
- patient with hair loss/baldness
- age of 20-70 years old
Exclusion Criteria:
- patient with systemic disorder
- phyco
- patient with coagulation abnormality
- patient with inflammation
Study Plan
How is the study designed?
Design Details
- Primary Purpose: TREATMENT
- Allocation: NA
- Interventional Model: SINGLE_GROUP
- Masking: NONE
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
EXPERIMENTAL: platelet-rich plasma
hair loss, baldness
|
hair loss, baldness
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What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
examination the effect of PRP on hair loss/baldness
Time Frame: 1 month
|
We will track and evaluate regularly the effect and efficiency of PRP on human hair growing density and newly-formed hair length by phtography and measurement.
|
1 month
|
Collaborators and Investigators
Study record dates
Study Major Dates
Study Start
Primary Completion (ACTUAL)
Study Completion (ACTUAL)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (ESTIMATE)
Study Record Updates
Last Update Posted (ESTIMATE)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- CMUH102-REC1-111
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
Clinical Trials on Hair Loss/Baldness
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Applied Biology, Inc.WithdrawnAndrogenetic Alopecia | Hair Loss | Hair Loss/Baldness | Female Pattern BaldnessUnited States
-
StimuSILAnkara City Hospital Bilkent; Istanbul University - Cerrahpasa (IUC)RecruitingAndrogenetic Alopecia | Hair Loss | Male Pattern Baldness | Hair Loss/Baldness | Pattern BaldnessTurkey
-
Kaohsiung Medical University Chung-Ho Memorial...CompletedFemale Pattern Alopecia | Androgenic Alopecia | Male Pattern Baldness | Hair Loss/BaldnessTaiwan
-
Pak Medical and Diagnostic CenterNot yet recruitingHair Loss/Baldness
-
University of MinnesotaWithdrawnAndrogenetic Alopecia | Male Pattern Baldness | Male Pattern Hair LossUnited States
-
Lebanese UniversityReviva Regenerative Medicine Center MEIH Hospital - REVIVA PHARMACEUTICALS...UnknownAlopecia | Hair Loss/BaldnessLebanon
-
Institute of Dermatology, ThailandCompletedAndrogenetic Alopecia | Hair Loss/BaldnessThailand
-
Arbor Life LabsCompletedAndrogenetic Alopecia | Androgenic Alopecia | Hair Loss/Baldness | Hair Thinning | Telogen Effluvium | Thinning HairUnited States
-
Energenesis Biomedical Co., Ltd.A2 Healthcare Taiwan CorporationCompleted
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Lexington International, LLCCompletedAndrogenetic Alopecia | Hair Loss | Female Pattern BaldnessUnited States
Clinical Trials on hair loss, baldness (patient's own platelet-rich plasma)
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Healeon Medical IncTerry, Glenn C., M.D.; Ministry of Health, Honduras; Robert W. Alexander, MDEnrolling by invitation