PERFECT Project - Part 2 - Study 3

Pulse EnRiched Food and Exercise Clinical Trials (PERFECT Project): Part 2 - Acute Effects of Pulse Ingredients in Food Products on Aerobic Endurance and Substrate Oxidation During Exercise, as Well as, the Blood Glucose, Insulin, Lactate and Food Intake Response Following an Endurance Exercise Session in Adults - Study 3

The objectives are to test the acute effects of different bagels containing pulse ingredients on: 1) aerobic endurance and substrate oxidation during exercise 2) response of blood glucose, insulin and appetite to an aerobic exercise session, and 3) food intake two hours following the exercise session. We hypothesize that consumption of bagels containing pulse ingredients 60 minutes before exercise will increase aerobic endurance (lower oxygen consumption), decrease carbohydrate oxidation (greater respiratory quotient), and a reduction in lactate production during compared to the same exercise session following the ingestion of a non-pulse food. We also hypothesize that consumption of bagels containing pulse ingredients will lead to lower blood glucose, insulin, appetite and food intake, suggesting lower calorie compensation, following a 60-minute aerobic exercise session compared to the same exercise session following the ingestion of a non-pulse food.

Study Overview

• Status: Completed
• Conditions: Diabetes Prevention; Obesity Prevention
• Intervention / Treatment: Other: Control; Other: Pea flour; Other: Pea fibre; Other: Pea flour and pea fibre; Other: Pea flour and pea protein; Other: Pea flour + pea fibre + pea protein

• Study Type: Interventional
• Enrollment (Actual): 30
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Canada
  • Manitoba
    • Winnipeg, Manitoba, Canada, R3T 6C5
      • Richardson Centre for Functional Foods and Nutraceuticals, University of Manitoba

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 45 years (Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

Description

• Normoglycemic (<5.6 mmol/L) and normotensive (systolic blood pressure <140 mm Hg and diastolic blood pressure below < 90 mm Hg)
• BMI of 18.5-29.9 kg/m2

Exclusion Criteria:

• Restrained eaters
• Regularly skip breakfast
• Smokers
• Those who are active (organized activities or athletic training at a high intensity; ≥ 150 min per week of moderate to vigorous physical activity)
• Those on medications that may influence study outcomes or have experienced any gastrointestinal related health conditions/surgeries over the past year
• Those unable to walk for an hour continuously

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Other
• Allocation: Randomized
• Interventional Model: Crossover Assignment
• Masking: Triple

Number of Arms

6

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Bagel control; 100% wheat flour	Other: Control; Non pulse ingredient bagel
Experimental: Bagel with pea flour; Pea flour (30%)	Other: Pea flour; Pulse ingredient bagel
Experimental: Bagel with pea fibre; Pea fibre (11g)	Other: Pea fibre; Pulse ingredient bagel
Experimental: Bagel w/ pea flour + pea fibre; Pea flour (30%) + pea fibre (11g)	Other: Pea flour and pea fibre; Pulse ingredient bagel
Experimental: Bagel w/ pea flour + pea protein; Pea flour (30%) + pea protein (24g)	Other: Pea flour and pea protein; Pulse ingredient bagel
Experimental: Bagel w/ pea flour + pea fibre + pea protein; Pea flour (30%) + pea fibre (11g) + pea protein (24g)	Other: Pea flour + pea fibre + pea protein; Pulse ingredient bagel

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Subjective Appetite	Motivation-to-eat VAS questionnaire	0-240 min
Exercise intensity	Oxygen consumption measured during exercise at 3 time points	60-120 min
Plasma Glucose and Insulin Concentrations	Measured in blood using intravenous catheter. Glucose will be determined by automated methods using Abbot Spectrum CCX Analyzer, and Insulin will be measured by commercially available RIA kits	0-240
Food Intake	Ad-libitum meal	120 min

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Heart rate	To monitor exercise intensity and give a measure of fatigue (cardiovascular drift)	60-120 min
Substrate Oxidation	Respiratory quotient measured during exercise at 3 time points	60-120 min
Palatability	Measured by VAS questionnaire	5 and 260 min
Physical comfort	Measured by VAS questionnaire	0-240 min
Energy/fatigue	Measured by VAS questionnaire	0 - 240 min
Lactate concentration	Measured before, during, and exercise exercise at 3 time points	60-120 min

Collaborators and Investigators

• Sponsor: University of Manitoba
• Collaborators: Saskatchewan Pulse Growers; Alberta Pulse Growers

Study record dates

Study Major Dates

• Study Start: October 1, 2016
• Primary Completion (Actual): December 19, 2017
• Study Completion (Actual): December 19, 2017

Study Registration Dates

• First Submitted: December 17, 2014
• First Submitted That Met QC Criteria: February 10, 2015
• First Posted (Estimate): February 18, 2015

Study Record Updates

• Last Update Posted (Actual): January 23, 2023
• Last Update Submitted That Met QC Criteria: January 19, 2023
• Last Verified: April 1, 2021

More Information

Terms related to this study

• Other Study ID Numbers: B2014:114-6