Osteoporosis Associated Vertebral Fractures - Medical and Socio-economic Aspects in Austria

The purposes of this study were to analyse demographic, medical, gender and socio-economic aspects of osteoporosis associated vertebral fractures.

Study Overview

• Status: Completed
• Conditions: Osteoporotic Fractures
• Intervention / Treatment: Procedure: Operation; Procedure: Non-operative treatment

• Study Type: Observational
• Enrollment (Actual): 694

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 50 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

This study was a retrospective case series of 694 patients, in which the fracture was caused due to primary or secondary osteoporosis, and who were treated at the department of trauma surgery at our level-I trauma center.

Description

Inclusion Criteria:

-patients older than 50 years of age with vertebral fractures at the thoracic or lumbar spine caused by a low-energy trauma or without any trauma, or with vertebral fractures at the thoracic or lumbar spine with typical osteoporotic deformity of the vertebrae (wedge, fish, or flat)

Exclusion Criteria:

• patients younger than 50 years of age
• vertebral fractures at the cervical spine
• vertebral fractures at the thoracic or lumbar spine caused by a high-energy trauma (motor-vehicle accident, sports-related accident, fall from a considerable height)
• patients suffering from a malignancy, making a pathological fracture presumably, patients with vertebral fractures, whose dataset of follow-up monitoring was lacking, to make an evaluation of osteoporotic involvement impossible

Study Plan

How is the study designed?

Design Details

• Time Perspectives: Retrospective

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
osteoporosis associated vertebral fractures; Analyzation of demographic, medical, gender and socio-economic aspects of osteoporosis associated vertebral fractures.	Procedure: Operation; Analyzation of demographic, medical, gender and socio-economic aspects of osteoporosis associated vertebral fractures treated with operation.; Procedure: Non-operative treatment; Analyzation of demographic, medical, gender and socio-economic aspects of osteoporosis associated vertebral fractures treated with non-operative treatment.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
demographic aspects	demographic aspects (age, social status) of osteoporosis associated vertebral fractures treated with either operation or non operative treatment	at least two year follow up
gender aspects	gender aspects (sex) of osteoporosis associated vertebral fractures treated with either operation or non operative treatment	at least two year follow up
socio economic aspects	socio-economic aspects (cost ratio) of osteoporosis associated vertebral fractures treated with either operation or non operative treatment	at least two year follow up

Collaborators and Investigators

• Sponsor: Medical University of Vienna

Study record dates

Study Major Dates

• Study Start: January 1, 2011
• Primary Completion (Actual): March 1, 2015

Study Registration Dates

• First Submitted: March 20, 2015
• First Submitted That Met QC Criteria: March 25, 2015
• First Posted (Estimate): March 31, 2015

Study Record Updates

• Last Update Posted (Estimate): March 31, 2015
• Last Update Submitted That Met QC Criteria: March 25, 2015
• Last Verified: March 1, 2015

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Fractures, Bone; Wounds and Injuries; Osteoporotic Fractures
• Other Study ID Numbers: 2011/896