- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT02747212
Measuring the Electrical Properties of Malignant Tissues Ex Vivo
October 11, 2018 updated by: Sherman Xuegang Xin, Southern Medical University, China
Measuring the Electrical Properties of the Excised Malignant Tissues Obtained From Cancer Surgeries
Previously published studies have indicated that there exist difference in electrical properties (EPs), i.e., the conductivity and relative permittivity, between malignant and adjacent normal tissue, which will be useful in the early detection of cancers.
While the EP informations of cancer tissues are not sufficient enough.
The purpose of this study is to measure the electrical properties of the excised malignant tissues obtained from cancer surgeries.
Study Overview
Detailed Description
The measurements were conducted in the operating rooms of the hospital where the tissues were excised.
Once the tissue was excised from the patient, the pathologist assisted the one of the engineers (already at the hospital) responsible to conduct the measurement.
The specimen were designed to permit at least one measurement of malignant tissue and at least one measurement of normal tissue.
Occasionally, the measurement of normal tissue was not possible if, for example, the normal tissue occupied a volume of small proportion for every excised specimen.
The specimens for dielectric properties measurement were classified as normal or malignant by the pathologist based on his own expertise and decision criteria (visual inspection, anatomy) and the per-operative histological examination.
The measurements were directly performed on the bulk specimen.
The patient age, tissue temperature at the time of measurement and time between excision and measurement for each sample were recorded.
Study Type
Observational
Enrollment (Anticipated)
200
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
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Guangdong
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Guangzhou, Guangdong, China, 510280
- Zhujiang Hospital
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Child
- Adult
- Older Adult
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Sampling Method
Probability Sample
Study Population
The patients who are diagnosed with cancer disease and about to have an operation to excise the cancer tissues
Description
Inclusion Criteria:
- Clinical diagnosis of cancer Disease
Exclusion Criteria:
- None
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
Conductivity of Malignant Tissues Measured Ex Vivo
Time Frame: one year
|
one year
|
Relative Permittivity of Malignant Tissues Measured Ex Vivo
Time Frame: one year
|
one year
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Collaborators
Investigators
- Principal Investigator: Sherman X Xin, professor, School of Biomedical Engineering,Southern Medical University
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
General Publications
- Surowiec AJ, Stuchly SS, Barr JB, Swarup A. Dielectric properties of breast carcinoma and the surrounding tissues. IEEE Trans Biomed Eng. 1988 Apr;35(4):257-63. doi: 10.1109/10.1374. No abstract available.
- Athey T W, Stuchly M A and Stuchly S S. Measurement of radio frequency permittivity of biological tissues with an open-ended coaxial line: Part I. Microwave Theory and Techniques, IEEE Transactions on IEEE Trans 30(1): 82-86, 1982.
- Bobowski Jake S, Johnson Thomas. Permittivity measurements of biological samples by an open-ended coaxial line. Progress In Electromagnetics Research B 40: 159-183, 2012.
- Smith SR, Foster KR, Wolf GL. Dielectric properties of VX-2 carcinoma versus normal liver tissue. IEEE Trans Biomed Eng. 1986 May;33(5):522-4. doi: 10.1109/TBME.1986.325740. No abstract available.
- Mehta P, Chand K, Narayanswamy D, Beetner D G, Zoughi R and Stoecker W V. Microwave reflectometry as a novel diagnostic tool for detection of skin cancers IEEE Trans. Instrum. Meas. 55: 1309-16, 2006
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Anticipated)
December 1, 2018
Primary Completion (Anticipated)
August 1, 2019
Study Completion (Anticipated)
January 1, 2020
Study Registration Dates
First Submitted
February 22, 2016
First Submitted That Met QC Criteria
April 18, 2016
First Posted (Estimate)
April 21, 2016
Study Record Updates
Last Update Posted (Actual)
October 12, 2018
Last Update Submitted That Met QC Criteria
October 11, 2018
Last Verified
October 1, 2018
More Information
Terms related to this study
Other Study ID Numbers
- SXXin-EPs-measurement-ex vivo
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
UNDECIDED
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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