Identifying Barriers and Strategies to Support Self-efficacy for Medication Adherence With Text Messaging

Identifying Patient-centered Barriers and Preferred Strategies to Support Self-efficacy for Medication Adherence With Two-way Text Messaging

The investigators will explore barriers to improving self-efficacy, or the ability to feel in control of their disease, and medication adherence with text messaging through surveys and interviews with adolescents and adults with SCD cared for at the Vanderbilt Meharry Center of Excellence (VMCE) in Sickle Cell Disease (SCD). The investigators will identify preferences to improve and sustain adherence to daily medication through selection of investigator-proposed or patient-generated text messaging strategies. Finally, the investigators will fill in the literature gaps by describing barriers to self-efficacy and medication adherence among adults with SCD as well as adolescents with SCD who are transitioning to adult care.

Study Overview

• Status: Active, not recruiting
• Conditions: Sickle Cell Disease
• Intervention / Treatment: Other: Interviews and Surveys

• Study Type: Observational
• Enrollment (Actual): 70

Contacts and Locations

Study Locations

• United States
  • Tennessee
    • Nashville, Tennessee, United States, 37203
      • Vanderbilt University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 12 years to 70 years (Child, Adult, Older Adult)
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

The investigators will assess barriers to self-efficacy and medication adherence in the adolescents and adults with sickle cell disease (SCD), asthma, or both, who take daily medications such as hydroxyurea, asthma, or both, have access to mobile phones and/or computers and receive care at the VUMC/Matthew Walker clinic.

Description

Inclusion Criteria:

1. Receiving care at the VUMC/Matthew Walker clinic
2. Diagnosed with SCD, asthma, or both
3. Currently taking daily medications for SCD, such as hydroxyurea, asthma, or both
4. Having access to a mobile telephone and/or computer
5. Age 12-70 years

Exclusion Criteria:

1. Unable to perform interviews or surveys

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Asthma and/or Sickle Cell Anemia; The investigators will examine patients with sickle cell disease, asthma, or both who are aged 12-70 years who take daily medications.	Other: Interviews and Surveys; The investigators will perform semi-structured interviews and surveys on this cohort

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Number of patients with barriers to medication adherence	High cost, forgetting, side effects, access to medications	1 year

Secondary Outcome Measures

Outcome Measure	Time Frame
Number of patients that prefer a tailored text messaging technological solution	1 year

Collaborators and Investigators

• Sponsor: Vanderbilt University
• Investigators: Principal Investigator: Robert Cronin, MD, MS, Vanderbilt University

Study record dates

Study Major Dates

• Study Start: May 1, 2016
• Primary Completion (Actual): May 1, 2022
• Study Completion (Estimated): July 1, 2024

Study Registration Dates

• First Submitted: May 25, 2016
• First Submitted That Met QC Criteria: May 27, 2016
• First Posted (Estimated): May 30, 2016

Study Record Updates

• Last Update Posted (Actual): September 5, 2023
• Last Update Submitted That Met QC Criteria: September 1, 2023
• Last Verified: September 1, 2023

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Hematologic Diseases; Genetic Diseases, Inborn; Anemia; Anemia, Hemolytic, Congenital; Anemia, Hemolytic; Hemoglobinopathies; Anemia, Sickle Cell
• Other Study ID Numbers: 160750