Validation of the French Adaptation of the RAADS-R Scale : Scale of Asperger Syndrome Diagnosis (RAADS-R)

Validation of the French Adaptation of the Scale Aiding in the Diagnosis of the Autism Spectrum Disorders : Scale of Asperger Syndrome Diagnosis

The diagnosis of developmental disorders in adults is still difficult. Indeed, in France, there is not questionnaires to easily and accurately diagnose this disorder. Several diagnostic scales were developed in English. Among them, RAADS-R scale, which is a clinical tool that aims to better identify autism spectrum disorders including mild forms in adult people and help to diagnose of high-functioning autism . The objective of this study is to perform a complete validation of this scale in the french version.

Study Overview

• Status: Completed
• Conditions: Autism Spectrum Disorder
• Intervention / Treatment: Other: RAADS-R scale

Detailed Description

The diagnosis of developmental disorders in adults is still difficult. Indeed, in France, there is not questionnaires to easily and accurately diagnose this disorder. Several diagnostic scales were developed in English. Among them, RAADS-R scale, which is a clinical tool that aims to better identify autism spectrum disorders including mild forms in adult people and help to diagnose of high-functioning autism . This scale is a self-administered questionnaire completed by the person himself assisted by a clinician (psychiatrist, psychologist) which ensures the understanding of issues and the choice of answers. The scale contains 80 items including 64 questions describe specific symptoms of autism spectrum disorders and 16 questions describe non-symptomatic behaviors. The objective of this study is to perform a complete validation of this scale in the french version. 300 adults should be included, including 100 adults with high-functioning autism, 100 adults with another psychiatric disorder, and 100 adults without developmental disabilities and / or mental.

• Study Type: Interventional
• Enrollment (Actual): 324
• Phase: Not Applicable

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 75 years (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• Non-specific criteria
• Collection of the informed consent (patient or legal representant)
• Affiliation or recipient with the mode of social security
• Current reading skills evaluated by completion of the fact sheet attached to the scale
• Age limits to > 18 years and < 75 years

Specific criteria

• Group of adult subjects with autism

  • Diagnosis of autism or Asperger syndrome established within the framework of a multidisciplinary evaluation (ADOS module 4 and/or ADI) using specific international classification criteria of rare diseases (CIM 10, DSM IV-R) (F84.0 et F84.5).
  • Intellectual efficiency estimated by means of a psychometric tool standardized (WAIS, WASI) greater than or equal to 85
  • Subjects not denying their symptoms

• Group of adult subjects with other psychiatric

  • Diagnosis of an other psychiatric trouble established according to the specific international classification criteria of mental diseases (CIM 10, DSM IV).
  • absence of pervasive developmental disorder diagnosis
  • Subjects not denying their symptoms
• Group of adult subjects not carriers of development and/or psychiatric disorders

Exclusion Criteria:

• Women pregnant and Breast-feeding
• Persons deprived of freedom by court order

Specific criteria

• Group of adult subjects with autism

  • Refusal of participation
  • absence of autism or Asperger syndrome diagnosis

• Group of adult subjects with other psychiatric

  • Refusal of participation
  • Pervasive developmental disorder diagnosis

• Group of adult subjects not carriers of development and/or psychiatric disorders

  • Refusal of participation
  • Diagnosis of cognitive development or psychomotor disorder, diagnosis of retard mental and/or psychiatric disorder.

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Diagnostic
• Allocation: N/A
• Interventional Model: Single Group Assignment
• Masking: None (Open Label)

Number of Arms

1

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Other: Patients with autism disorder; The RAADS-R scale is a self-administered questionnaire completed by the patient himself assisted by a clinician	Other: RAADS-R scale; This scale is a self-administered questionnaire completed by the person himself assisted by a clinician

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
score at the RAADS-R scale	The scale contains 80 items including 64 questions describe specific symptoms of autism spectrum disorders and 16 questions describe non-symptomatic behaviors	15 days

Collaborators and Investigators

• Sponsor: University Hospital, Montpellier
• Collaborators: Fondation Orange
• Investigators: Principal Investigator: Amaria BAGHDADLI, MD-PhD, University Hospital, Montpellier

Study record dates

Study Major Dates

• Study Start: December 1, 2011
• Primary Completion (Actual): December 1, 2015
• Study Completion (Actual): December 1, 2015

Study Registration Dates

• First Submitted: July 5, 2016
• First Submitted That Met QC Criteria: July 5, 2016
• First Posted (Estimate): July 7, 2016

Study Record Updates

• Last Update Posted (Estimate): July 7, 2016
• Last Update Submitted That Met QC Criteria: July 5, 2016
• Last Verified: March 1, 2016

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Mental Disorders; Neurodevelopmental Disorders; Child Development Disorders, Pervasive; Autism Spectrum Disorder; Asperger Syndrome
• Other Study ID Numbers: 8747 (Other Identifier: CTEP)

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: No

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: No