Does Mixing Alcoholic Drinks Make Hangover Worse?

April 23, 2018 updated by: Zealand University Hospital

Does Mixing Alcoholic Drinks Make Hangover Worse? A Randomized Controlled Trial in a Naturalistic Setting

Does mixing alcohol make hangover worse?

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Hangover is the most commonly occurring morbidity associated with heavy drinking.

Our aim was to test the hypothesis that mixing alcoholic drinks as compared to drinking one type of alcohol only (beer, wine or spirits) associate with a higher alcohol intake and worse hangover.

Study Type

Interventional

Enrollment (Actual)

35

Phase

  • Not Applicable

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years and older (ADULT, OLDER_ADULT)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • written and oral consent
  • minimum 18 years old
  • participating in Danish Health Research Retreat in Turkey 2016
  • will consume alcoholic beverages

Exclusion Criteria:

  • underage
  • will not consume alcoholic beverages

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: HEALTH_SERVICES_RESEARCH
  • Allocation: RANDOMIZED
  • Interventional Model: PARALLEL
  • Masking: TRIPLE

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
EXPERIMENTAL: single type
Restricted to drinking only one type of alcohol
Dietary supplement: Single type alcohol
Alcoholic beverages, different types
Other Names:
  • Ethanol
ACTIVE_COMPARATOR: mixed type
Drinking and mixing different types of alcohols freely
Dietary supplement: Mixing alcohol
Alcoholic beverages, different types
Other Names:
  • Ethanol

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Acute Hangover Severity Scale (AHSS)
Time Frame: Baseline
AHSS is a 12-item alcohol hangover measurement tool recommended for application in hangover research with a predictive validity of 92.4 %, significantly higher than that of other hangover scales (Penning et al., 2012). Alcohol hangover was measured thrice the day after drinking; in the morning immediately after waking up, at midday, and in the afternoon. The individual participant assessed his or her own hangover the day after.
Baseline

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Number of drinks
Time Frame: Baseline
Total number of drinks defined as 12 g of alcohol consumed during evening
Baseline
Acute Hangover Severity Scale (AHSS) 2
Time Frame: after 4 hours
AHSS is a 12-item alcohol hangover measurement tool recommended for application in hangover research with a predictive validity of 92.4 %, significantly higher than that of other hangover scales (Penning et al., 2012). Alcohol hangover was measured thrice the day after drinking; in the morning immediately after waking up, at midday, and in the afternoon. The individual participant assessed his or her own hangover the day after.
after 4 hours
Acute Hangover Severity Scale (AHSS) 3
Time Frame: after 8 hours
AHSS is a 12-item alcohol hangover measurement tool recommended for application in hangover research with a predictive validity of 92.4 %, significantly higher than that of other hangover scales (Penning et al., 2012). Alcohol hangover was measured thrice the day after drinking; in the morning immediately after waking up, at midday, and in the afternoon. The individual participant assessed his or her own hangover the day after.
after 8 hours

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Zealand University Hospital

Investigators

  • Principal Investigator: Ole G Christiansen, MD, Zealand University Hospital

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (ACTUAL)

May 20, 2016

Primary Completion (ACTUAL)

May 30, 2016

Study Completion (ACTUAL)

January 31, 2018

Study Registration Dates

First Submitted

February 12, 2018

First Submitted That Met QC Criteria

April 23, 2018

First Posted (ACTUAL)

April 24, 2018

Study Record Updates

Last Update Posted (ACTUAL)

April 24, 2018

Last Update Submitted That Met QC Criteria

April 23, 2018

Last Verified

April 1, 2018

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • VEK16028829

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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