Metabolic Equivalent of Task (MET) in the Preoperative Assessment in Aortic Surgery

August 3, 2018 updated by: Alicja Zientara, Triemli Hospital

Reliable prediction of the preoperative risk is of crucial importance for patients undergoing vascular operations. The assessment of the metabolic equivalent of task (MET) is an easy clinical evaluation of the functional capacity of an individual. A MET is defined as the resting metabolic rate, that is the amount of the consumed oxygen at rest. According to the MET concept a patient would be considered as "fit for surgery" when the stairs of two flights can be climbed and the housework can be fully managed by oneself.

Hypothesis: Patients with a functional capacity over 4 MET (fit for surgery) have less perioperative complications with the focus on cardiac pathology than patients with less than 4 MET during aortic operations.

Patients and Method: Retrospective analysis of a single center unit of 296 patients undergoing open or endovascular aortic repair.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Actual)

296

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

16 years to 88 years (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Probability Sample

Study Population

296 patients who received an aortic repair with open or endovascular technique at Triemli Hospital from May 2009 till March 2016

Description

Inclusion Criteria:

  • Data of all patients after open and endovascular aortic repair of the descending aorta from May 2009 till March 2016

Exclusion Criteria:

  • Data of all patients with isolated operations on the ascending aorta or aortic arch

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Observational Models: Cohort
  • Time Perspectives: Retrospective

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
> 4 MET
Patients with functional capacity over 4 MET
Diagnostic test: MET
Testing of the metabolic equivalent of task before aortic procedure
< 4 MET
Patients with functional capacity under 4 MET
Diagnostic test: MET
Testing of the metabolic equivalent of task before aortic procedure

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Survival
Time Frame: up to ten years
Mean survival during the whole follow up period of both groups, patients with less and more than 4 MET
up to ten years

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Perioperative complications
Time Frame: up to 30 days postoperatively
Complications include perioperative myocardial infarction and stroke, re-operation during first admission (divided in greater and smaller re-operations)
up to 30 days postoperatively
Coronary artery bypass grafting, percutaneous coronary intervention/Stenting
Time Frame: up to ten years
Interventions including revascularisation or other kind of heart surgery or treatment because of cardiac pathology
up to ten years

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Triemli Hospital

Investigators

  • Study Chair: Nicolas Attigah, MD, Triemli Hospital Zurich

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

May 1, 2009

Primary Completion (Actual)

August 1, 2016

Study Completion (Actual)

January 1, 2018

Study Registration Dates

First Submitted

July 6, 2018

First Submitted That Met QC Criteria

August 3, 2018

First Posted (Actual)

August 6, 2018

Study Record Updates

Last Update Posted (Actual)

August 6, 2018

Last Update Submitted That Met QC Criteria

August 3, 2018

Last Verified

July 1, 2018

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • KEK-ZH-Nr: 2017-00801

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

No

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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