Antibiotic Stewardship in Infectious Disease Departement

Adherence to Anti-infectious Treatment Protocols in Emergencies and Short-term Hospitalization at the Infectious Disease Department"

Consensual antibiotic protocols have been developed and validated locally by infectious disease specialists, internists and emergency physicians, in order to encourage their compliance. A preliminary study was conducted from June 2015 to February 2016, including 622 patients admitted to the emergency department for infectious syndrome such as /

• Pneumoniae
• Urinary tract infection
• Cellulitis
• Meningitis
• Malaria
• Febrile neutropenia
• Febrile acute diarrhea
• Fever back to the tropics
• Angina
• sexually transmitted infection This prospective study will observe and analyze the adherence of prescribers to these protocols. With description of patients who benefited or not the antibiotic protocol, according to a syndromic approach and analysis of the causes of non-adherence to the protocols. In order to limit the length of stay and reduce the cost of hospitalization..

Study Overview

• Status: Unknown
• Conditions: Infectious Disease
• Intervention / Treatment: Other: antibiotic protocol, according to a syndromic approach

Detailed Description

Consensual antibiotic protocols have been developed and validated locally by infectious disease specialists, internists and emergency physicians, in order to encourage their compliance. A preliminary study was conducted from June 2015 (setting up protocols) to February 2016, including 622 patients admitted to the emergency department for infectious syndrome such as /

• Pneumoniae
• Urinary tract infection
• Cellulitis
• Meningitis
• Malaria
• Febrile neutropenia
• Febrile acute diarrhea
• Fever back to the tropics
• Angina
• sexually transmitted infection This prospective study will observe and analyze the adherence of prescribers to these protocols. With description of patients who benefited or not the antibiotic protocol, according to a syndromic approach and analysis of the causes of non-adherence to the protocols. In order to limit the length of stay and reduce the cost of hospitalization..

• Study Type: Observational
• Enrollment (Anticipated): 2000

Contacts and Locations

Study Locations

• France
  • Paca
    • Marseille, Paca, France, 13005
      • Assistance Publique Des Hopitaux de Marseille

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (ADULT, OLDER_ADULT)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

Patients who present a infectious syndrom

Description

Inclusion Criteria:

• Patient admitted to emergency for infectious syndrome
• Patient > 18 years old.
• Patient who accept to have his medical records reviewed for research.

Exclusion Criteria:

• Patient < 18 years old.

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
experimental group; • Patient admitted to emergency for infectious syndrome Description of antibiotic protocol, according to a syndromic approach will be performed	Other: antibiotic protocol, according to a syndromic approach; Description of patients who benefited or not the antibiotic protocol, according to a syndromic approach and analysis of the causes of non-adherence to the protocols

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
List of Antibiotic treatment	Description of the prescribed antibiotic treatment depending of infectious syndrome: name, duration for each treatment during hospitalization Data will be collected in the medical files: date of introduction of antibiotic treatment; withdrawal dates; stop dates; antibiotic classes	up to 12 weeks
Adverse events	Description of the cause of non adherence to antibiotic treatment initiates at hospital admission of antibiotherapy: Data will be collected in the medical files of patients: events leading to withdrawal or stop treatment (insufficiency renal, allergic reaction ... etc) date of events aggravation or recovery	up to 12 weeks

Collaborators and Investigators

• Sponsor: Assistance Publique Hopitaux De Marseille

Study record dates

Study Major Dates

• Study Start (ANTICIPATED): September 1, 2018
• Primary Completion (ANTICIPATED): July 1, 2021
• Study Completion (ANTICIPATED): January 1, 2022

Study Registration Dates

• First Submitted: July 9, 2018
• First Submitted That Met QC Criteria: August 16, 2018
• First Posted (ACTUAL): August 17, 2018

Study Record Updates

• Last Update Posted (ACTUAL): August 17, 2018
• Last Update Submitted That Met QC Criteria: August 16, 2018
• Last Verified: August 1, 2018

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Pathologic Processes; Disease Attributes; Infections; Communicable Diseases; Anti-Infective Agents; Anti-Bacterial Agents
• Other Study ID Numbers: 2018-24

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No