Epidemiologic Features of Kawasaki Disease in Shanghai From 2013 Through 2017

Epidemiologic Features of Kawasaki Disease in Shanghai From 2013 Through 2017

Sponsors

Lead Sponsor: Children's Hospital of Fudan University

Collaborator: Shanghai Children's Hospital
Shanghai Children's Medical Center
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine

Source Children's Hospital of Fudan University
Brief Summary

To investigate the epidemiologic features of Kawasaki disease (KD) in Shanghai from 2013 through 2017 and identify the risk factors for coronary artery lesions.

Detailed Description

Based on the KD research group network established during the first survey in Shanghai, a set of questionnaires and diagnostic guidelines for KD will be sent to 50 hospitals providing pediatric medical care in Shanghai, China. Medical records of participants with KD diagnosed from January 2013 through December 2017 will be retrospectively analyzed. Data are collected by pediatricians, including demographic information, clinical manifestations, prognosis, laboratory indexes, treatment and echocardiographic findings.

Age and seasonal distribution at onset, treatment and cardiac abnormalities wil be described. Univariate and multivariate analyses will be performed to identify risk factors for coronary artery lesions.

Overall Status Completed
Start Date June 1, 2017
Completion Date March 1, 2019
Primary Completion Date January 1, 2019
Study Type Observational
Primary Outcome
Measure Time Frame
Incidence of coronary artery lesions from admission to one month after onset
Secondary Outcome
Measure Time Frame
Incidence of intravenous immunoglobulin resistance from admision to discharge (about two weeks after onset)
Risk factors associated with coronary artery lesions from admisson to one month after onset
Enrollment 4533
Condition
Intervention

Intervention Type: Other

Intervention Name: no intervention

Description: no intervention

Eligibility

Sampling Method: Non-Probability Sample

Criteria:

Inclusion Criteria:

- meeting the diagnostic criteria for Kawasaki disease released by American Heart Association 2017

Exclusion Criteria:

- not in acute phase;

- repeated cases;

Gender: All

Minimum Age: N/A

Maximum Age: N/A

Healthy Volunteers: No

Overall Official
Last Name Role Affiliation
Fang Liu, Dr. Principal Investigator Children's Hospital of Fudan University
Location
Facility: Children's Hospital of Fudan University
Location Countries

China

Verification Date

March 2019

Responsible Party

Type: Sponsor

Keywords
Has Expanded Access No
Condition Browse
Patient Data No
Study Design Info

Observational Model: Case-Only

Time Perspective: Retrospective

Source: ClinicalTrials.gov