- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT04155827
Gender Specific Responses of Overweight and Obese Adults to Sprint Interval Training
November 22, 2020 updated by: Imtiyaz Ali Mir, Universiti Tunku Abdul Rahman
Gender Specific Responses of Overweight and Obese Adults to Sprint Interval Training on Anthropometric Variables
Overweight and Obesity is a growing health problem worldwide.
Lifestyle changes such as decreased physical activity, increased sedentary behaviour and unhealthy eating habits has contribute to this problem.
According to World Health Organization (2016), more than 1.9 billion adults aged 18 years and older were overweight (39% of men and 40% of women).Regular exercise is the key contributor to energy expenditure and is essential for energy balance and weight control.
Interval training (IT) has been commonly used for decades with purpose to improve body health and reduce weight loss and this exercise differs from the conventional aerobic exercise and endurance exercise as IT typically involves repeated bouts of relatively intense exercise interspersed by periods of lower- intensity effort or complete rest for recovery.
One of the most common type of IT is sprint interval training (SIT).
SIT involves 'supramaximal' effort (>100% VO2max) work bouts, traditionally structured as four to six 30s all-out effort and each round separated by 4 minutes of recovery period of a low intensity exercise.
Potential physiological adaptation of SIT are highlighted by various studies reporting cardiovascular, skeletal muscle adaptations, increase fat oxidation that facilitate increases in both aerobic and anaerobic performance.
In addition, SIT is able to improve maximal rate of oxygen consumption (VO2max), at the same time improving the peripheral vascular structure and function, enzymes of fat metabolism and increases insulin sensitivity.
Previous SIT studies have included young healthy men and women, healthy obese young women, all of which have shown that SIT is effective for fat loss and improvement of some health parameters.
However, whether SIT protocol is equally effective in improving the anthropometric measures in men and women remain unknown.
Study Overview
Detailed Description
Total of 80 eligible male (n=40) and female (n=40) young adults will be equally recruited using block randomization and chosen based on the inclusion and exclusion criteria.
Before the study, all participants will be informed of the potential risks and benefits of the study.
During the study period, participants will be instructed to avoid any form of physical activity besides the study protocol.
Both groups will perform SIT protocol on a electromagnetically braked cycle ergometer three times per week for 6 weeks.
Every session, participants start with a 5 minutes warm up at 50- 60% of heart rate maximum (HRmax) and follow by four 30-s all out bouts intersperse with 4 minutes of recovery (passive or no load cycling).
For confirmation of all-out effort, participant are required to maintain his or her cycling cadence at least 60 rpm or above.
Intervention will end with a 5 minutes cool down at 50- 60% of HRmax.
Total duration for each session will be 28 minutes.
If a participant misses fewer than three sessions per week non- consecutively, the sessions missed will be replace at the end of period.
However, if participants misses three or more sessions, he or she will be excluded from the study.
Outcome measures will be assessed at baseline and at end of 6 weeks of intervention.
Study Type
Interventional
Enrollment (Actual)
35
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
Selangor
-
Kajang, Selangor, Malaysia, 43000
- Universiti Tunku Abdul Rahman
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years to 25 years (Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Description
Inclusion Criteria:
- BMI≧23kg/m2(WHO for Asia-Pacific region)
- No history of metabolic, hormonal, orthopedic, or cardiovascular diseases
- No current use of prescribed medication including oral contraception
Exclusion Criteria:
- Contraindications to physical activity assessed by Physical Activity Readiness Questionnaire-PAR-Q
- Undergoes any surgical or hormone treatment
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Non-Randomized
- Interventional Model: Parallel Assignment
- Masking: Single
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Experimental: SIT for males
|
Sprint interval training of 4*4, with 30 seconds of all out workout followed by 4 minutes of active recovery for 4 cycles.
|
Experimental: SIT for females
|
Sprint interval training of 4*4, with 30 seconds of all out workout followed by 4 minutes of active recovery for 4 cycles.
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
BMI for change
Time Frame: At baseline (before intervention begin) and post training (end of 6 weeks).
|
At baseline (before intervention begin) and post training (end of 6 weeks).
|
Waist Circumference for change
Time Frame: At baseline (before intervention begin) and post training (end of 6 weeks).
|
At baseline (before intervention begin) and post training (end of 6 weeks).
|
Total Fat % for change
Time Frame: At baseline (before intervention begin) and post training (end of 6 weeks).
|
At baseline (before intervention begin) and post training (end of 6 weeks).
|
Lean Muscle Mass for change
Time Frame: At baseline (before intervention begin) and post training (end of 6 weeks).
|
At baseline (before intervention begin) and post training (end of 6 weeks).
|
skin Fold Measurement for change
Time Frame: At baseline (before intervention begin) and post training (end of 6 weeks).
|
At baseline (before intervention begin) and post training (end of 6 weeks).
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
February 4, 2020
Primary Completion (Actual)
November 16, 2020
Study Completion (Actual)
November 23, 2020
Study Registration Dates
First Submitted
November 4, 2019
First Submitted That Met QC Criteria
November 5, 2019
First Posted (Actual)
November 7, 2019
Study Record Updates
Last Update Posted (Actual)
November 24, 2020
Last Update Submitted That Met QC Criteria
November 22, 2020
Last Verified
November 1, 2020
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- UMFB1001
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
No
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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